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TMEM185A Antibody – Rabbit

For Research Use Only. Not for use in diagnostic procedures. Catalog #: MBS003945

MBS003945 is an antibody targeting TMEM185A. Also known as Rabbit TMEM185A Antibody. Reactive in Human, mouse. Host: Rabbit. More details

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Product Documentation
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Sample Manual Insert View PDF
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Testing Data View PDF
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Certificate of Analysis (COA) View PDF
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QC Report View PDF
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Material Safety Data Sheet View PDF
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Technical Datasheet View PDF
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Protocol View PDF

Product Overview

Product Name
TMEM185A, Antibody
Full Product Name
Rabbit TMEM185A Antibody
Product Gene Name
Host
Rabbit
Species Reactivity
Human, mouse
Form/Format
Phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol
Concentration
1 mg/ml (lot specific)
Molecular Weight
40,647 Da
Chromosome Location
Chromosome: X; NC_000023.10 (148678216..148713487, complement). Location: Xq28
OMIM
300031
3D Structure
ModBase 3D Structure for Q8NFB2
Applications Tested/Suitable for anti-TMEM185A antibody
ELISA (EIA), Immunofluorescence (IF), Western Blot (WB)

Other Notes

Small volumes of anti-TMEM185A antibody vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.

Additional Details

NCBI/Uniprot data below describe general gene information for TMEM185A. It may not necessarily be applicable to this product.

NCBI GI #
NCBI GeneID
NCBI Accession #
UniProt Primary Accession #
UniProt Secondary Accession #
UniProt Related Accession #
GenBank Nucleotide #
NCBI Official Full Name
transmembrane protein 185A isoform 2
NCBI Official Synonym Full Names
transmembrane protein 185A
NCBI Official Symbol
TMEM185A
NCBI Official Synonym Symbols
FRAXF; FAM11A; CXorf13
UniProt Protein Name
Transmembrane protein 185A
UniProt Synonym Protein Names
Protein FAM11A
Protein Family
UniProt Gene Name
TMEM185A
UniProt Synonym Gene Names
CXorf13; FAM11A
UniProt Entry Name
T185A_HUMAN
NCBI Protein Information
transmembrane protein 185A; ee3; family with sequence similarity 11, member A; fragile site, folic acid type, rare, fra(X)(q28) F

NCBI Summary for TMEM185A

The protein encoded by this gene is predicted to be a transmembrane protein, but this has not been experimentally determined. This gene is better known for localizing to the CpG island of the fragile site FRAXF. The 5-prime untranslated region of this gene contains a CGG trinucleotide repeat sequence that normally consists of 7-40 tandem CGG repeats but which can expand to greater than 300 repeats. Methylation of the CpG island leads to transcriptional silencing of this gene, but neither the silencing nor an expanded repeat region appear to manifest itself in a clear phenotypic manner. Two transcript variants encoding different isoforms have been found for this gene.[provided by RefSeq, Mar 2010]
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UniProt Comments for TMEM185A

TMEM185A: is predicted to be a transmembrane protein, but this has not been experimentally determined. This gene is better known for localizing to the CpG island of the fragile site FRAXF. The 5-prime untranslated region of this gene contains a CGG trinucleotide repeat sequence that normally consists of 7-40 tandem CGG repeats but which can expand to greater than 300 repeats. Methylation of the CpG island leads to transcriptional silencing of this gene, but neither the silencing nor an expanded repeat region appear to manifest itself in a clear phenotypic manner. Two transcript variants encoding different isoforms have been found for this gene.[provided by RefSeq, Mar 2010]

Protein type: Membrane protein, multi-pass

Chromosomal Location of Human Ortholog: Xq28

Cellular Component: dendrite; integral to membrane

Molecular Function: protein binding
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Precautions

All of MyBioSource's Products are for scientific laboratory research purposes and are not for diagnostic, therapeutics, prophylactic or in vivo use. Through your purchase, you expressly represent and warrant to MyBioSource that you will properly test and use any Products purchased from MyBioSource in accordance with industry standards. MyBioSource and its authorized distributors reserve the right to refuse to process any order where we reasonably believe that the intended use will fall outside of our acceptable guidelines.

Disclaimer

While every efforts were made to ensure the accuracy of the information provided in this datasheet, MyBioSource will not be liable for any omissions or errors contained herein. MyBioSource reserves the right to make changes to this datasheet at any time without prior notice.

It is the responsibility of the customer to report product performance issues to MyBioSource within 30 days of receipt of the product. Please visit our Terms & Conditions page for more information.

Product Note

Select online data sheet information is drawn from bioinformatics databases, occasionally resulting in ambiguous or non-relevant product information. It is the responsibility of the customer to review, verify, and evaluate the information to make sure it matches their requirements before purchasing the kit. Our ELISA Kit assays are dynamic research tools and sometimes they may be updated and improved. If the format of this assay is important to you then please request the current manual or contact our technical support team with a presales inquiry before placing an order. We will confirm the current details of the assay. We cannot guarantee the sample manual posted online is the most current manual, it is intended to serve as an example only. Please refer to the instructions For Use provided with the assay kit for precise details.

Product PubMed Publications

Diseases associated with anti-TMEM185A antibody

 Disease Name  Pubmed Publications
 Neoplasms Antibodies  >1 publications with TMEM185A and Neoplasms

Organs/Tissues associated with anti-TMEM185A antibody

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