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RASA3 Antibody – Rabbit

For Research Use Only. Not for use in diagnostic procedures. Catalog #: MBS003946

MBS003946 is an antibody targeting RASA3. Also known as Rabbit RASA3 Antibody. Reactive in Human, mouse, rat. Host: Rabbit. More details

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Product Documentation
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Sample Manual Insert View PDF
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Testing Data View PDF
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Certificate of Analysis (COA) View PDF
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QC Report View PDF
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Material Safety Data Sheet View PDF
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Technical Datasheet View PDF
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Protocol View PDF

Product Overview

Product Name
RASA3, Antibody
Full Product Name
Rabbit RASA3 Antibody
Product Gene Name
Host
Rabbit
Species Reactivity
Human, mouse, rat
Form/Format
Phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol
Concentration
1 mg/ml (lot specific)
Molecular Weight
95,699 Da
Chromosome Location
Chromosome: 13; NC_000013.10 (114747194..114898095, complement). Location: 13q34
OMIM
605182
3D Structure
ModBase 3D Structure for Q14644
Applications Tested/Suitable for anti-RASA3 antibody
ELISA (EIA), Western Blot (WB)

Other Notes

Small volumes of anti-RASA3 antibody vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.

Additional Details

NCBI/Uniprot data below describe general gene information for RASA3. It may not necessarily be applicable to this product.

NCBI GI #
NCBI GeneID
NCBI Accession #
UniProt Primary Accession #
UniProt Secondary Accession #
UniProt Related Accession #
GenBank Nucleotide #
NCBI Official Full Name
ras GTPase-activating protein 3
NCBI Official Synonym Full Names
RAS p21 protein activator 3
NCBI Official Symbol
RASA3
NCBI Official Synonym Symbols
GAPIII; GAP1IP4BP
UniProt Protein Name
Ras GTPase-activating protein 3
UniProt Synonym Protein Names
GAP1(IP4BP); Ins P4-binding protein
UniProt Gene Name
RASA3
UniProt Entry Name
RASA3_HUMAN
NCBI Protein Information
ras GTPase-activating protein 3; GAP1(IP4BP); ins P4-binding protein; GTPase activating protein III; Ins(1,3,4,5)P4-binding protein; inositol 1,3,4,5-tetrakisphosphate-binding protein

NCBI Summary for RASA3

The protein encoded by this gene is member of the GAP1 family of GTPase-activating proteins. The gene product stimulates the GTPase activity of normal RAS p21 but not its oncogenic counterpart. Acting as a suppressor of RAS function, the protein enhances the weak intrinsic GTPase activity of RAS proteins resulting in the inactive GDP-bound form of RAS, thereby allowing control of cellular proliferation and differentiation. This family member is an inositol 1,3,4,5-tetrakisphosphate-binding protein, like the closely related RAS p21 protein activator 2. The two family members have distinct pleckstrin-homology domains, with this particular member having a domain consistent with its localization to the plasma membrane. [provided by RefSeq, Jul 2008]
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UniProt Comments for RASA3

RASA3: Inhibitory regulator of the Ras-cyclic AMP pathway. Binds inositol tetrakisphosphate (IP4) with high affinity. Might be a specific IP4 receptor.

Protein type: GAPs, Ras; GAPs

Chromosomal Location of Human Ortholog: 13q34

Cellular Component: cytoplasm

Molecular Function: metal ion binding; calcium-release channel activity; GTPase activator activity

Biological Process: negative regulation of Ras protein signal transduction; signal transduction
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Precautions

All of MyBioSource's Products are for scientific laboratory research purposes and are not for diagnostic, therapeutics, prophylactic or in vivo use. Through your purchase, you expressly represent and warrant to MyBioSource that you will properly test and use any Products purchased from MyBioSource in accordance with industry standards. MyBioSource and its authorized distributors reserve the right to refuse to process any order where we reasonably believe that the intended use will fall outside of our acceptable guidelines.

Disclaimer

While every efforts were made to ensure the accuracy of the information provided in this datasheet, MyBioSource will not be liable for any omissions or errors contained herein. MyBioSource reserves the right to make changes to this datasheet at any time without prior notice.

It is the responsibility of the customer to report product performance issues to MyBioSource within 30 days of receipt of the product. Please visit our Terms & Conditions page for more information.

Product Note

Select online data sheet information is drawn from bioinformatics databases, occasionally resulting in ambiguous or non-relevant product information. It is the responsibility of the customer to review, verify, and evaluate the information to make sure it matches their requirements before purchasing the kit. Our ELISA Kit assays are dynamic research tools and sometimes they may be updated and improved. If the format of this assay is important to you then please request the current manual or contact our technical support team with a presales inquiry before placing an order. We will confirm the current details of the assay. We cannot guarantee the sample manual posted online is the most current manual, it is intended to serve as an example only. Please refer to the instructions For Use provided with the assay kit for precise details.

Product PubMed Publications

Pathways associated with anti-RASA3 antibody

 Products by Pathway  Pathway Diagram
 MAPK Cascade Pathway antibodies  MAPK Cascade Pathway Diagram

Diseases associated with anti-RASA3 antibody

 Disease Name  Pubmed Publications
 Neoplasms Antibodies  >1 publications with RASA3 and Neoplasms
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