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KRT7 Antibody – Mouse Monoclonal

For Research Use Only. Not for use in diagnostic procedures. Catalog #: MBS245806

MBS245806 is an antibody targeting KRT7. Also known as Mouse Monoclonal [clone RCK105] (IgG1) to Human KRT7 / CK7 / Cytokeratin 7. Reactive in Cat, Dog, Hamster, Human, Mouse, Pig, Rat. Host: Mouse. More details

$650 / 0.05 mg +1 FREE 8GB USB
Product Documentation
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Sample Manual Insert View PDF
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Testing Data View PDF
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Certificate of Analysis (COA) View PDF
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QC Report View PDF
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Material Safety Data Sheet View PDF
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Technical Datasheet View PDF
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Protocol View PDF

Product Overview

Online Datasheet in PDF
Product Name
KRT7 / CK7 / Cytokeratin 7, Monoclonal Antibody
Full Product Name
Mouse Monoclonal [clone RCK105] (IgG1) to Human KRT7 / CK7 / Cytokeratin 7
Product Gene Name
Product Synonym Names
Anti-KRT7 / CK7 / Cytokeratin 7 Antibody (clone RCK105) IHC-plus; KRT7; CK-7; Cytokeratin 7; CK7; K2C7; K7; Keratin 7; Keratin-7; SCL; Type II mesothelial keratin K7; Cytokeratin-7; Sarcolectin; Type-II keratin Kb7; Human KRT7; CK7; Cytokeratin 7
Clonality
Monoclonal
Isotype
IgG1
Clone Number
RCK105
Host
Mouse
Species Reactivity
Cat, Dog, Hamster, Human, Mouse, Pig, Rat
Form/Format
PBS containing 0.09% sodium azide
Purity/Purification
Purified
Concentration
1 mg/ml (lot specific)
Specificity
Reacts exclusively with cytokeratin 7 which is present in a subgroup of glandular epithelia and their tumors, as well as transitional epithelium and transitional carcinoma.
Preparation and Storage
Short term 4 degree C, long term aliquot and store at -20 degree C, avoid freeze thaw cycles. Store undiluted.
Molecular Weight
51,386 Da
OMIM
148059
Target Species
Human
Immunogen Description
Cytokeratins from the human bladder carcinoma cell line T24
Applications Tested/Suitable for anti-KRT7 antibody
Immunohistochemistry (IHC - Paraffin; IHC - Frozen), Immunocytochemistry (ICC), Western Blot (WB), Flow Cytometry (FC/FACS)
Application Notes for anti-KRT7 antibody
Flo (1:100 - 1:200), ICC, IHC-Fr (1:100 - 1:200), IHC-P (10 ug/ml), WB (1:100 - 1:1000)

Immunohistochemistry (IHC) of anti-KRT7 antibody

Anti-KRT7 / Cytokeratin 7 antibody IHC of human placenta. Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval. Antibody concentration 10 ug/ml.
Mouse Anti-KRT7 Monoclonal Antibody – Cat# MBS245806

Immunohistochemistry (IHC) of anti-KRT7 antibody

Immunohistochemistry on frozen sections of human liver, only bile duct epithelium positive; no reaction in hepatocytes
Mouse Anti-KRT7 Monoclonal Antibody, Immunohistochemistry (IHC) – Cat# MBS245806

Immunohistochemistry (IHC) of anti-KRT7 antibody

Immunohistochemistry on frozen sections of swine liver, only bile duct epithelium positive; no reaction in hepatocytes
Mouse Anti-KRT7 Monoclonal Antibody, Immunohistochemistry (IHC) – Cat# MBS245806

Other Notes

Small volumes of anti-KRT7 antibody vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.

Additional Details

NCBI/Uniprot data below describe general gene information for KRT7. It may not necessarily be applicable to this product.

NCBI GI #
NCBI GeneID
NCBI Accession #
UniProt Secondary Accession #
UniProt Related Accession #
GenBank Nucleotide #
NCBI Official Full Name
keratin, type II cytoskeletal 7
NCBI Official Synonym Full Names
keratin 7
NCBI Official Symbol
KRT7
NCBI Official Synonym Symbols
K7; CK7; SCL; K2C7
UniProt Protein Name
Keratin, type II cytoskeletal 7
UniProt Synonym Protein Names
Cytokeratin-7; CK-7; Keratin-7; K7; Sarcolectin; Type-II keratin Kb7
Protein Family
UniProt Gene Name
KRT7
UniProt Synonym Gene Names
SCL; CK-7; K7
UniProt Entry Name
K2C7_HUMAN
NCBI Protein Information
keratin, type II cytoskeletal 7; CK-7; keratin-7; sarcolectin; cytokeratin 7; cytokeratin-7; type-II keratin Kb7; type II mesothelial keratin K7; keratin, 55K type II cytoskeletal; keratin, simple epithelial type I, K7

NCBI Summary for KRT7

The protein encoded by this gene is a member of the keratin gene family. The type II cytokeratins consist of basic or neutral proteins which are arranged in pairs of heterotypic keratin chains coexpressed during differentiation of simple and stratified epithelial tissues. This type II cytokeratin is specifically expressed in the simple epithelia lining the cavities of the internal organs and in the gland ducts and blood vessels. The genes encoding the type II cytokeratins are clustered in a region of chromosome 12q12-q13. Alternative splicing may result in several transcript variants; however, not all variants have been fully described. [provided by RefSeq, Jul 2008]
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UniProt Comments for KRT7

K7: a type II cytoskeletal keratin. The keratins are intermediate filament proteins responsible for the structural integrity of epithelial cells and are subdivided into cytokeratins and hair keratins. Phosphorylation of keratins at specific sites affects their organization, assembly dynamics, and their interaction with signaling molecules. Specifically expressed in the simple epithelia lining the cavities of the internal organs and in the gland ducts and blood vessels.

Protein type: Cytoskeletal

Chromosomal Location of Human Ortholog: 12q13.13

Cellular Component: keratin filament; cytoplasm; intermediate filament; nucleus

Molecular Function: protein binding; structural molecule activity

Biological Process: viral reproduction
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Precautions

All of MyBioSource's Products are for scientific laboratory research purposes and are not for diagnostic, therapeutics, prophylactic or in vivo use. Through your purchase, you expressly represent and warrant to MyBioSource that you will properly test and use any Products purchased from MyBioSource in accordance with industry standards. MyBioSource and its authorized distributors reserve the right to refuse to process any order where we reasonably believe that the intended use will fall outside of our acceptable guidelines.

Disclaimer

While every efforts were made to ensure the accuracy of the information provided in this datasheet, MyBioSource will not be liable for any omissions or errors contained herein. MyBioSource reserves the right to make changes to this datasheet at any time without prior notice.

It is the responsibility of the customer to report product performance issues to MyBioSource within 30 days of receipt of the product. Please visit our Terms & Conditions page for more information.

Product Note

Select online data sheet information is drawn from bioinformatics databases, occasionally resulting in ambiguous or non-relevant product information. It is the responsibility of the customer to review, verify, and evaluate the information to make sure it matches their requirements before purchasing the kit. Our ELISA Kit assays are dynamic research tools and sometimes they may be updated and improved. If the format of this assay is important to you then please request the current manual or contact our technical support team with a presales inquiry before placing an order. We will confirm the current details of the assay. We cannot guarantee the sample manual posted online is the most current manual, it is intended to serve as an example only. Please refer to the instructions For Use provided with the assay kit for precise details.

Product PubMed Publications

Pathways associated with anti-KRT7 antibody

 Products by Pathway  Pathway Diagram
 EGFR1 Signaling Pathway antibodies  EGFR1 Signaling Pathway Diagram
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