Mouse Anti-a/b SNAP Monoclonal Antibody – Cat# MBS395170

Western blot (10% SDS-PAGE) of chicken brain (lane 1), chicken kidney (lane 2), rat brain (lane 3) and rat kidney (lane 4) probed with clone 16D1 anti- / SNAP at 0.2 g/ml.

a/b SNAP Antibody – Mouse Monoclonal

Name: a/b SNAP Antibody; Monoclonal; Mouse; MyBioSource
Brand: MyBioSource
SKU: MBS395170
Price: 430 USD
Availability: InStock
Rating: 5 (10 reviews)

For Research Use Only. Not for use in diagnostic procedures. Catalog #: MBS395170

38 kDa SNAPs (soluble NSF attachment proteins), acting in concert with SNAREs (SNAP receptors) and the N-ethylmaleimide- More details

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Product Documentation

Sample Manual Insert View PDF

Testing Data View PDF

Certificate of Analysis (COA) View PDF

QC Report View PDF

Material Safety Data Sheet View PDF

Technical Datasheet View PDF

Protocol View PDF

Product Overview

Product Name

a/b SNAP, Monoclonal Antibody

Full Product Name

a/b SNAP

Product Gene Name

anti-a/b SNAP antibody

Product Synonym Names

alpha/beta SNAP; mouse anti alpha/beta soluble NSF attachment protein

Clonality

Monoclonal

Isotype

IgG2b

Clone Number

16D1

Host

Mouse

Species Reactivity

Human, Rat, Bovine, Chicken

Form/Format

20 mM sodium phosphate, 150 mM sodium chloride, 50% glycerol, pH 7.5

Preparation and Storage

Product should be stored at -20 degree C. Aliquot to avoid freeze/thaw cycles

Molecular Weight

Chromosome Location

Chromosome: 19; NC_000019.9 (47990891..48018515, complement). Location: 19q13.33

OMIM

603215

3D Structure

ModBase 3D Structure for P54920

Immunogen

Recombinant human alpha SNAP

Positive Control

Rat brain

Product Categories/Family for anti-a/b SNAP antibody

Monoclonal Antibody; Neuronal Signaling

Applications Tested/Suitable for anti-a/b SNAP antibody

Western Blot (WB)

Other Notes

Small volumes of anti-a/b SNAP antibody vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.

Searchable Terms for a/b SNAP purchase

MBS395170 is an antibody targeting a/b SNAP. Reactive in Human, Rat, Bovine, Chicken. Host: Mouse.

Additional Details

NCBI/Uniprot data below describe general gene information for a/b SNAP. It may not necessarily be applicable to this product.

NCBI GI #

47933379

NCBI GeneID

8775

NCBI Accession #

NP_003818.2

UniProt Primary Accession #

P54920

UniProt Secondary Accession #

Q96IK3; Q9BVJ3; A8K879

UniProt Related Accession #

P54920

GenBank Nucleotide #

NM_003827.3

NCBI Official Full Name

alpha-soluble NSF attachment protein

NCBI Official Synonym Full Names

N-ethylmaleimide-sensitive factor attachment protein, alpha

NCBI Official Symbol

NAPA

NCBI Official Synonym Symbols

SNAPA

UniProt Protein Name

Alpha-soluble NSF attachment protein

UniProt Synonym Protein Names

N-ethylmaleimide-sensitive factor attachment protein alpha

Protein Family

Alpha-soluble NSF attachment protein

UniProt Gene Name

NAPA

UniProt Synonym Gene Names

SNAPA; SNAP-alpha

UniProt Entry Name

SNAA_HUMAN

NCBI Protein Information

alpha-soluble NSF attachment protein; alpha-SNAP

NCBI Summary for a/b SNAP

This gene encodes a member of the soluble NSF attachment protein (SNAP) family. SNAP proteins play a critical role in the docking and fusion of vesicles to target membranes as part of the 20S NSF-SNAP-SNARE complex. The encoded protein plays a role in the completion of membrane fusion by mediating the interaction of N-ethylmaleimide-sensitive factor (NSF) with the vesicle-associated and membrane-associated SNAP receptor (SNARE) complex, and stimulating the ATPase activity of NSF. Alternatively spliced transcript variants have been observed for this gene. [provided by RefSeq, Jun 2011]

UniProt Comments for a/b SNAP

Function: Required for vesicular transport between the endoplasmic reticulum and the Golgi apparatus.

Subunit structure: Interacts with PRKCABP, and disrupts the interaction between GRIA2 and PRKCABP, leading to the internalization of GRIA2. Found in a complex with VAMP8

By similarity. Component of a SNARE-like complex that contains at least ZW10, USE1L, RINT1, STX18 and NAPA/SNAP-alpha. Interacts with VTI1A. Interacts with STX12

By similarity. Ref.7

Subcellular location: Membrane; Peripheral membrane protein.

Sequence similarities: Belongs to the SNAP family.

Research Articles on a/b SNAP

1. Study revealed a novel role for alphaSNAP as a negative regulator of autophagy that acts by enhancing mTOR signaling and regulating the integrity of the Golgi complex.

Precautions

All of MyBioSource's Products are for scientific laboratory research purposes and are not for diagnostic, therapeutics, prophylactic or in vivo use. Through your purchase, you expressly represent and warrant to MyBioSource that you will properly test and use any Products purchased from MyBioSource in accordance with industry standards. MyBioSource and its authorized distributors reserve the right to refuse to process any order where we reasonably believe that the intended use will fall outside of our acceptable guidelines.

Disclaimer

While every efforts were made to ensure the accuracy of the information provided in this datasheet, MyBioSource will not be liable for any omissions or errors contained herein. MyBioSource reserves the right to make changes to this datasheet at any time without prior notice.

It is the responsibility of the customer to report product performance issues to MyBioSource within 30 days of receipt of the product. Please visit our Terms & Conditions page for more information.

Product Note

Select online data sheet information is drawn from bioinformatics databases, occasionally resulting in ambiguous or non-relevant product information. It is the responsibility of the customer to review, verify, and evaluate the information to make sure it matches their requirements before purchasing the kit. Our ELISA Kit assays are dynamic research tools and sometimes they may be updated and improved. If the format of this assay is important to you then please request the current manual or contact our technical support team with a presales inquiry before placing an order. We will confirm the current details of the assay. We cannot guarantee the sample manual posted online is the most current manual, it is intended to serve as an example only. Please refer to the instructions For Use provided with the assay kit for precise details.

Product PubMed Publications

Products associated with anti-a/b SNAP antibody

Reference Product	PubMed Publications
NSF antibody	>2 publications with a/b SNAP and NSF
SNAP25 antibody	>1 publications with a/b SNAP and SNAP25
VAMP2 antibody	>1 publications with a/b SNAP and VAMP2
STX1A antibody	>1 publications with a/b SNAP and STX1A

Pathways associated with anti-a/b SNAP antibody

Products by Pathway	Pathway Diagram
Clathrin Derived Vesicle Budding Pathway antibodies	Clathrin Derived Vesicle Budding Pathway Diagram
Golgi Associated Vesicle Biogenesis Pathway antibodies	Golgi Associated Vesicle Biogenesis Pathway Diagram
Membrane Trafficking Pathway antibodies	Membrane Trafficking Pathway Diagram
Synaptic Vesicle Pathway antibodies	Synaptic Vesicle Pathway Diagram
Synaptic Vesicle Cycle Pathway antibodies	Synaptic Vesicle Cycle Pathway Diagram
Synaptic Vesicle Cycle Pathway antibodies	Synaptic Vesicle Cycle Pathway Diagram
Trans-Golgi Network Vesicle Budding Pathway antibodies	Trans-Golgi Network Vesicle Budding Pathway Diagram

Diseases associated with anti-a/b SNAP antibody

Disease Name	Pubmed Publications
Cardiovascular Diseases Antibodies	>61 publications with a/b SNAP and Cardiovascular Diseases
Nervous System Diseases Antibodies	>43 publications with a/b SNAP and Nervous System Diseases
Neoplasms Antibodies	>39 publications with a/b SNAP and Neoplasms
Drug Toxicity Antibodies	>30 publications with a/b SNAP and Drug Toxicity
Poisoning Antibodies	>20 publications with a/b SNAP and Poisoning
Kidney Diseases Antibodies	>18 publications with a/b SNAP and Kidney Diseases
Breast Neoplasms Antibodies	>14 publications with a/b SNAP and Breast Neoplasms
Inflammation Antibodies	>10 publications with a/b SNAP and Inflammation
Adenocarcinoma Antibodies	>9 publications with a/b SNAP and Adenocarcinoma
Disease Models, Animal Antibodies	>8 publications with a/b SNAP and Disease Models, Animal

Organs/Tissues associated with anti-a/b SNAP antibody

Organ/Tissue Name	Pubmed Publications
Blood Antibodies	>134 publications with a/b SNAP and Blood
Heart Antibodies	>61 publications with a/b SNAP and Heart
Kidney Antibodies	>44 publications with a/b SNAP and Kidney
Brain Antibodies	>34 publications with a/b SNAP and Brain
Liver Antibodies	>25 publications with a/b SNAP and Liver
Muscle Antibodies	>19 publications with a/b SNAP and Muscle
Vascular Antibodies	>14 publications with a/b SNAP and Vascular
Nerve Antibodies	>10 publications with a/b SNAP and Nerve
Skin Antibodies	>9 publications with a/b SNAP and Skin
Bone Antibodies	>8 publications with a/b SNAP and Bone