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G 5-D1 Antibody – Rabbit Polyclonal

For Research Use Only. Not for use in diagnostic procedures. Catalog #: MBS395507

The Gbeta5 protein is a G protein subunit present predominantly in the central nervous system. This protein appears to be expressed in two forms, one found in the brain (39 kDa) and one found in the retina (44 kDa). It has also been found that Gb5 associates… More details

$500 / 0.1 mg +1 FREE 8GB USB
Product Documentation
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Sample Manual Insert View PDF
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Testing Data View PDF
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Certificate of Analysis (COA) View PDF
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QC Report View PDF
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Material Safety Data Sheet View PDF
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Technical Datasheet View PDF
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Protocol View PDF

Product Overview

Online Datasheet in PDF
Product Name
G 5-D1, Polyclonal Antibody
Full Product Name
G 5-D1
Product Gene Name
Clonality
Polyclonal
Isotype
IgG
Host
Rabbit
Species Reactivity
Murine, Rat, Human
Form/Format
Provided as solution in phosphate buffered saline with 0.08% sodium azide
Purity/Purification
Ammonium Sulfate Precipitation
Preparation and Storage
Product should be stored at -20 degree C. Aliquot to avoid freeze/thaw cycles
Molecular Weight
43,566 Da
Chromosome Location
Chromosome: 15; NC_000015.9 (52413123..52483565, complement). Location: 15q21.2
OMIM
604447
3D Structure
ModBase 3D Structure for O14775
Immunogen
Unique peptide sequence derived from the D1 blade of the G 5 protein.
Positive Control
Plasma membranes from rat cerebrum
Applications Tested/Suitable for anti-G 5-D1 antibody
Western Blot (WB)

Western Blot/Blotting of anti-G 5-D1 antibody

Western blot analysis using G 5 antibody on 20 ng (1) and 10 ng (2) purified G 5 protein.
Rabbit Anti-G 5-D1 Polyclonal Antibody – Cat# MBS395507

Other Notes

Small volumes of anti-G 5-D1 antibody vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.

Searchable Terms for G 5-D1 purchase

MBS395507 is an antibody targeting G 5-D1. Reactive in Murine, Rat, Human. Host: Rabbit.

Additional Details

NCBI/Uniprot data below describe general gene information for G 5-D1. It may not necessarily be applicable to this product.

NCBI GI #
NCBI GeneID
NCBI Accession #
UniProt Primary Accession #
UniProt Secondary Accession #
UniProt Related Accession #
GenBank Nucleotide #
NCBI Official Full Name
guanine nucleotide-binding protein subunit beta-5 isoform a
NCBI Official Synonym Full Names
guanine nucleotide binding protein (G protein), beta 5
NCBI Official Symbol
GNB5
NCBI Official Synonym Symbols
GB5
UniProt Protein Name
Guanine nucleotide-binding protein subunit beta-5
UniProt Synonym Protein Names
Gbeta5; Transducin beta chain 5
UniProt Gene Name
GNB5
UniProt Entry Name
GBB5_HUMAN
NCBI Protein Information
guanine nucleotide-binding protein subunit beta-5; gbeta5; transducin beta chain 5; G protein, beta-5 subunit; G protein, beta subunit 5L; guanine nucleotide-binding protein, beta subunit 5L

NCBI Summary for G 5-D1

Heterotrimeric guanine nucleotide-binding proteins (G proteins), which integrate signals between receptors and effector proteins, are composed of an alpha, a beta, and a gamma subunit. These subunits are encoded by families of related genes. This gene encodes a beta subunit. Beta subunits are important regulators of alpha subunits, as well as of certain signal transduction receptors and effectors. Alternatively spliced transcript variants encoding different isoforms exist. [provided by RefSeq, Jul 2008]
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UniProt Comments for G 5-D1

Function: Guanine nucleotide-binding proteins (G proteins) are involved as a modulator or transducer in various transmembrane signaling systems. The beta and gamma chains are required for the GTPase activity, for replacement of GDP by GTP, and for G protein-effector interaction.

Subunit structure: G proteins are composed of 3 units, alpha, beta and gamma. Component of the RGS9-1-Gbeta5 complex composed of RGS9 (isoform RGS9-1), Gbeta5 (GNB5) and RGS9BP

By similarity.

Tissue specificity: Expressed in multiple tissues.

Sequence similarities: Belongs to the WD repeat G protein beta family.Contains 7 WD repeats.
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Precautions

All of MyBioSource's Products are for scientific laboratory research purposes and are not for diagnostic, therapeutics, prophylactic or in vivo use. Through your purchase, you expressly represent and warrant to MyBioSource that you will properly test and use any Products purchased from MyBioSource in accordance with industry standards. MyBioSource and its authorized distributors reserve the right to refuse to process any order where we reasonably believe that the intended use will fall outside of our acceptable guidelines.

Disclaimer

While every efforts were made to ensure the accuracy of the information provided in this datasheet, MyBioSource will not be liable for any omissions or errors contained herein. MyBioSource reserves the right to make changes to this datasheet at any time without prior notice.

It is the responsibility of the customer to report product performance issues to MyBioSource within 30 days of receipt of the product. Please visit our Terms & Conditions page for more information.

Product Note

Select online data sheet information is drawn from bioinformatics databases, occasionally resulting in ambiguous or non-relevant product information. It is the responsibility of the customer to review, verify, and evaluate the information to make sure it matches their requirements before purchasing the kit. Our ELISA Kit assays are dynamic research tools and sometimes they may be updated and improved. If the format of this assay is important to you then please request the current manual or contact our technical support team with a presales inquiry before placing an order. We will confirm the current details of the assay. We cannot guarantee the sample manual posted online is the most current manual, it is intended to serve as an example only. Please refer to the instructions For Use provided with the assay kit for precise details.

Product PubMed Publications

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