• Call +1.858.633.0165 or Fax +1.858.633.0166 or Contact Us

Degenerative Spermatocyte Homolog 2 (DEGS2) Antibody – Rabbit Polyclonal

For Research Use Only. Not for use in diagnostic procedures. Catalog #: MBS395537

Bifunctional enzyme which acts as both a sphingolipid delta(4)-desaturase and a sphingolipid C4-hydroxylase. Up-regulated during keratinocyte differentiation. Not expressed at day 0 or day 3 after differentiation, detected on day 6 and increases by day 9.… More details

$500 / 0.1 mg +1 FREE 8GB USB
Product Documentation
PDF
Sample Manual Insert View PDF
PDF
Testing Data View PDF
PDF
Certificate of Analysis (COA) View PDF
PDF
QC Report View PDF
PDF
Material Safety Data Sheet View PDF
PDF
Technical Datasheet View PDF
PDF
Protocol View PDF

Product Overview

Online Datasheet in PDF
Product Name
Degenerative Spermatocyte Homolog 2 (DEGS2), Polyclonal Antibody
Full Product Name
Degenerative Spermatocyte Homolog 2
Product Gene Name
Product Synonym Names
DEGS2; Sphingolipid delta(4)-desaturase/C4-hydroxylase DES2
Clonality
Polyclonal
Host
Rabbit
Species Reactivity
Human
Form/Format
Provided as solution in phosphate buffered saline with 0.08% sodium azide
Purity/Purification
Ammonium Sulfate Precipitation
Preparation and Storage
Product should be stored at -20 degree C. Aliquot to avoid freeze/thaw cycles
Molecular Weight
37 kDa
Chromosome Location
Chromosome: 14; NC_000014.8 (100612753..100626012, complement). Location: 14q32.2
OMIM
610862
3D Structure
ModBase 3D Structure for Q6QHC5
Immunogen
Synthetic peptide derived from human DEGS2 protein.
Positive Control
Highly expressed in skin, intestine and kidney.

Product Categories/Family for anti-DEGS2 antibody

Applications Tested/Suitable for anti-DEGS2 antibody
Western Blot (WB)

Western Blot/Blotting of anti-DEGS2 antibody

Western blot using antigen immunoaffinity purified anti DEGS2 antibody on human kidney cell lysate. Lysate used at 15 ug/lane. Antibody used at 1:400 dilution. Secondary antibody, mouse anti-rabbit HRP , used at 1:50k dilution. Visualized using Pierce West Femto substrate system. Exposure for 5 minutes
Rabbit Anti-DEGS2 Polyclonal Antibody – Cat# MBS395537

Other Notes

Small volumes of anti-DEGS2 antibody vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.

Searchable Terms for DEGS2 purchase

MBS395537 is an antibody targeting DEGS2. Also known as Degenerative Spermatocyte Homolog 2. Reactive in Human. Host: Rabbit.

Additional Details

NCBI/Uniprot data below describe general gene information for DEGS2. It may not necessarily be applicable to this product.

NCBI GI #
NCBI GeneID
NCBI Accession #
UniProt Primary Accession #
UniProt Secondary Accession #
UniProt Related Accession #
GenBank Nucleotide #
NCBI Official Full Name
sphingolipid delta(4)-desaturase/C4-hydroxylase DES2
NCBI Official Synonym Full Names
delta(4)-desaturase, sphingolipid 2
NCBI Official Symbol
DEGS2
NCBI Official Synonym Symbols
DES2; FADS8; C14orf66
UniProt Protein Name
Sphingolipid delta(4)-desaturase/C4-hydroxylase DES2
UniProt Synonym Protein Names
Degenerative spermatocyte homolog 2
UniProt Gene Name
DEGS2
UniProt Synonym Gene Names
C14orf66
UniProt Entry Name
DEGS2_HUMAN
NCBI Protein Information
sphingolipid delta(4)-desaturase/C4-hydroxylase DES2; sphingolipid delta(4)-desaturase/C4-hydroxylase DES2; sphingolipid delta(4)-desaturase 2; sphingolipid C4-hydroxylase/delta 4-desaturase; sphingolipid delta 4 desaturase/C-4 hydroxylase; degenerative spermatocyte homolog 2, lipid desaturase

NCBI Summary for DEGS2

This gene encodes a bifunctional enzyme that is involved in the biosynthesis of phytosphingolipids in human skin and in other phytosphingolipid-containing tissues. This enzyme can act as a sphingolipid delta(4)-desaturase, and also as a sphingolipid C4-hydroxylase. [provided by RefSeq, Oct 2008]

UniProt Comments for DEGS2

Function: Bifunctional enzyme which acts as both a sphingolipid delta(4)-desaturase and a sphingolipid C4-hydroxylase

By similarity. UniProtKB Q8R2F2

Pathway: Membrane lipid metabolism; sphingolipid biosynthesis.

Subcellular location: Endoplasmic reticulum membrane; Multi-pass membrane protein

By similarity UniProtKB Q8R2F2.

Tissue specificity: Highly expressed in skin, intestine and kidney. Ref.1

Induction: Up-regulated during keratinocyte differentiation. Not expressed at day 0 or day 3 after differentiation, detected on day 6 and increases by day 9. Ref.1

Sequence similarities: Belongs to the fatty acid desaturase family. DEGS subfamily.
Show more

Precautions

All of MyBioSource's Products are for scientific laboratory research purposes and are not for diagnostic, therapeutics, prophylactic or in vivo use. Through your purchase, you expressly represent and warrant to MyBioSource that you will properly test and use any Products purchased from MyBioSource in accordance with industry standards. MyBioSource and its authorized distributors reserve the right to refuse to process any order where we reasonably believe that the intended use will fall outside of our acceptable guidelines.

Disclaimer

While every efforts were made to ensure the accuracy of the information provided in this datasheet, MyBioSource will not be liable for any omissions or errors contained herein. MyBioSource reserves the right to make changes to this datasheet at any time without prior notice.

It is the responsibility of the customer to report product performance issues to MyBioSource within 30 days of receipt of the product. Please visit our Terms & Conditions page for more information.

Product Note

Select online data sheet information is drawn from bioinformatics databases, occasionally resulting in ambiguous or non-relevant product information. It is the responsibility of the customer to review, verify, and evaluate the information to make sure it matches their requirements before purchasing the kit. Our ELISA Kit assays are dynamic research tools and sometimes they may be updated and improved. If the format of this assay is important to you then please request the current manual or contact our technical support team with a presales inquiry before placing an order. We will confirm the current details of the assay. We cannot guarantee the sample manual posted online is the most current manual, it is intended to serve as an example only. Please refer to the instructions For Use provided with the assay kit for precise details.

Product PubMed Publications

Request a Quote

Please fill out the form below and our representative will get back to you shortly.

MBS000000
Contact Us

Please fill out the form below and our representative will get back to you shortly.

MBS000000