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L-Type Calcium Channel Alpha2/Delta Subunit Antibody – Rabbit Polyclonal

For Research Use Only. Not for use in diagnostic procedures. Catalog #: MBS395577

The calcium channel alpha2/delta subunit is a glycosylated structural subunit consisting of the alpha2 subunit and the delta peptide. There is distinctive alpha2 subunit expression in rat spinal cord and dorsal root ganglia (DRG) There are two forms of the… More details

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Testing Data View PDF
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Technical Datasheet View PDF
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Product Overview

Online Datasheet in PDF
Product Name
L-type calcium channel alpha2/delta subunit (Cacna2d1), Polyclonal Antibody
Full Product Name
L-type calcium channel alpha2/delta subunit
Product Gene Name
Clonality
Polyclonal
Isotype
IgG
Host
Rabbit
Species Reactivity
Human, Rat
Form/Format
Provided as solution in phosphate buffered saline with 0.08% sodium azide
Purity/Purification
Ammonium Sulfate Precipitation
Preparation and Storage
Product should be stored at -20 degree C. Aliquot to avoid freeze/thaw cycles
Molecular Weight
122 kDa
Chromosome Location
Chromosome: 4; NC_005103.3 (15684827..16105448, complement). Location: 4q11
3D Structure
ModBase 3D Structure for Q8VHS9
Immunogen
Synthetic peptide derived from the rat alpha2/delta calcium channel conjugated to KLH
Positive Control
Rat brain lysate
Applications Tested/Suitable for anti-Cacna2d1 antibody
Western Blot (WB)

Western Blot/Blotting of anti-Cacna2d1 antibody

Western blot analysis using 2/ antibody on rat brain lysate at 5 ug/ml.
Rabbit Anti-L-Type Calcium Channel Alpha2/Delta Subunit Polyclonal Antibody – Cat# MBS395577

Other Notes

Small volumes of anti-Cacna2d1 antibody vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.

Searchable Terms for Cacna2d1 purchase

MBS395577 is an antibody targeting Cacna2d1. Also known as L-type calcium channel alpha2/delta subunit. Reactive in Human, Rat. Host: Rabbit.

Additional Details

NCBI/Uniprot data below describe general gene information for Cacna2d1. It may not necessarily be applicable to this product.

NCBI GI #
NCBI GeneID
NCBI Accession #
UniProt Primary Accession #
UniProt Related Accession #
GenBank Nucleotide #
NCBI Official Full Name
voltage-dependent calcium channel subunit alpha-2/delta-1 isoform 3
NCBI Official Synonym Full Names
calcium channel, voltage-dependent, alpha2/delta subunit 1
NCBI Official Symbol
Cacna2d1
NCBI Official Synonym Symbols
CCHLA2; Cacna2; DHSCCA
UniProt Protein Name
L-type calcium channel alpha2/delta subunit
UniProt Gene Name
Cacna2d1
UniProt Entry Name
Q8VHS9_RAT
NCBI Protein Information
voltage-dependent calcium channel subunit alpha-2/delta-1; voltage-gated calcium channel subunit alpha-2/delta-1; Calcium channel subunit alpha 2 delta (dihydropyridine - sensitive L-type)

NCBI Summary for Cacna2d1

subunit of voltage-gated calcium channels; contributes to the regulation of N- and/or L-type calcium channels [RGD, Feb 2006]

UniProt Comments for Cacna2d1

CACNA2D1: The alpha-2/delta subunit of voltage-dependent calcium channels regulates calcium current density and activation/inactivation kinetics of the calcium channel. Plays an important role in excitation-contraction coupling. Belongs to the calcium channel subunit alpha-2/delta family. 5 isoforms of the human protein are produced by alternative splicing.

Protein type: Membrane protein, integral; Channel, calcium

Cellular Component: sarcoplasmic reticulum; T-tubule; voltage-gated calcium channel complex

Molecular Function: voltage-gated calcium channel activity; protein binding; metal ion binding

Biological Process: calcium ion transport; regulation of calcium ion transport
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Precautions

All of MyBioSource's Products are for scientific laboratory research purposes and are not for diagnostic, therapeutics, prophylactic or in vivo use. Through your purchase, you expressly represent and warrant to MyBioSource that you will properly test and use any Products purchased from MyBioSource in accordance with industry standards. MyBioSource and its authorized distributors reserve the right to refuse to process any order where we reasonably believe that the intended use will fall outside of our acceptable guidelines.

Disclaimer

While every efforts were made to ensure the accuracy of the information provided in this datasheet, MyBioSource will not be liable for any omissions or errors contained herein. MyBioSource reserves the right to make changes to this datasheet at any time without prior notice.

It is the responsibility of the customer to report product performance issues to MyBioSource within 30 days of receipt of the product. Please visit our Terms & Conditions page for more information.

Product Note

Select online data sheet information is drawn from bioinformatics databases, occasionally resulting in ambiguous or non-relevant product information. It is the responsibility of the customer to review, verify, and evaluate the information to make sure it matches their requirements before purchasing the kit. Our ELISA Kit assays are dynamic research tools and sometimes they may be updated and improved. If the format of this assay is important to you then please request the current manual or contact our technical support team with a presales inquiry before placing an order. We will confirm the current details of the assay. We cannot guarantee the sample manual posted online is the most current manual, it is intended to serve as an example only. Please refer to the instructions For Use provided with the assay kit for precise details.

Product PubMed Publications

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