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GFRa-2 Antibody – Rabbit Polyclonal

For Research Use Only. Not for use in diagnostic procedures. Catalog #: MBS395607

Members of the glial cell line-derived neurotrophic factor (GDNF) family, including GDNF and neurturin (NTN)1, play key roles in the control of vertebrate neuron survival and differentiation. Physiological responses to NTN require the presence of a novel… More details

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Product Overview

Product Name
GFRa-2 (GDNFRb) (Neurturin receptor), Polyclonal Antibody
Full Product Name
GFRa-2 (IN) (GDNFRb) (Neurturin receptor)
Product Gene Name
Product Synonym Names
Rabbit anti-Glial Cell Derived Neurotrophic Factor Receptor -2 (Second Intracellular Loop); Human; Mouse; Rat
Clonality
Polyclonal
Isotype
IgG
Host
Rabbit
Species Reactivity
Human, Mouse, Rat
Form/Format
Provided in phosphate buffered saline solution containing 0.02% sodium azide as a preservative
Purity/Purification
Antigen Immunoaffiinity Purification
Preparation and Storage
Product should be stored at -20 degree C. Aliquot to avoid freeze/thaw cycles
Molecular Weight
52
3D Structure
ModBase 3D Structure for O08842
Immunogen
Synthetic peptide corresponding to amino acids 377 to 391 of human GFR -2. This sequence is identical to those of the mouse and rat.
Positive Control
HeLa whole cell lysate
Applications Tested/Suitable for anti-GFRa-2 antibody
Western Blot (WB)

Western Blot/Blotting of anti-GFRa-2 antibody

Western blot analysis
Rabbit Anti-GFRa-2 Polyclonal Antibody – Cat# MBS395607

Other Notes

Small volumes of anti-GFRa-2 antibody vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.

Searchable Terms for GFRa-2 purchase

MBS395607 is an antibody targeting GFRa-2. Also known as GFRa-2 (IN) (GDNFRb) (Neurturin receptor). Reactive in Human, Mouse, Rat. Host: Rabbit.

Additional Details

NCBI/Uniprot data below describe general gene information for GFRa-2. It may not necessarily be applicable to this product.

NCBI GI #
NCBI Accession #
UniProt Primary Accession #
NCBI Official Full Name
GDNF family receptor alpha-2
UniProt Protein Name
GDNF family receptor alpha-2
UniProt Synonym Protein Names
GDNF receptor beta; GDNFR-beta; Neurturin receptor alpha; NRTNR-alpha; NTNR-alpha; TGF-beta-related neurotrophic factor receptor 2
UniProt Gene Name
Gfra2
UniProt Synonym Gene Names
Gdnfrb; Trnr2; GDNF receptor alpha-2; GDNFR-alpha-2; GFR-alpha-2; GDNFR-beta; NRTNR-alpha; NTNR-alpha
UniProt Entry Name
GFRA2_MOUSE

UniProt Comments for GFRa-2

Function: Receptor for neurturin. Mediates the NRTN-induced autophosphorylation and activation of the RET receptor. Also able to mediate GDNF signaling through the RET tyrosine kinase receptor.

Subcellular location: Cell membrane; Lipid-anchor › GPI-anchor

By similarity.

Tissue specificity: Neurons of the superior cervical and dorsal root ganglia, and adult brain and testis. Low level in the spleen and in the adrenal gland.

Sequence similarities: Belongs to the GDNFR family.
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Precautions

All of MyBioSource's Products are for scientific laboratory research purposes and are not for diagnostic, therapeutics, prophylactic or in vivo use. Through your purchase, you expressly represent and warrant to MyBioSource that you will properly test and use any Products purchased from MyBioSource in accordance with industry standards. MyBioSource and its authorized distributors reserve the right to refuse to process any order where we reasonably believe that the intended use will fall outside of our acceptable guidelines.

Disclaimer

While every efforts were made to ensure the accuracy of the information provided in this datasheet, MyBioSource will not be liable for any omissions or errors contained herein. MyBioSource reserves the right to make changes to this datasheet at any time without prior notice.

It is the responsibility of the customer to report product performance issues to MyBioSource within 30 days of receipt of the product. Please visit our Terms & Conditions page for more information.

Product Note

Select online data sheet information is drawn from bioinformatics databases, occasionally resulting in ambiguous or non-relevant product information. It is the responsibility of the customer to review, verify, and evaluate the information to make sure it matches their requirements before purchasing the kit. Our ELISA Kit assays are dynamic research tools and sometimes they may be updated and improved. If the format of this assay is important to you then please request the current manual or contact our technical support team with a presales inquiry before placing an order. We will confirm the current details of the assay. We cannot guarantee the sample manual posted online is the most current manual, it is intended to serve as an example only. Please refer to the instructions For Use provided with the assay kit for precise details.

Product PubMed Publications

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