Rabbit Anti-LPPR4 Polyclonal Antibody – Cat# MBS395657

Western blot analysis using LPPRP4 antibody on human brain lysate.

Lipid Phosphate Phosphatase Related Protein 4 (LPPR4) Antibody – Rabbit Polyclonal

Name: LPPR4 Antibody; Polyclonal; Rabbit; Human-Reactive; MyBioSource
Brand: MyBioSource
SKU: MBS395657
Price: 500 USD
Availability: InStock
Rating: 5 (10 reviews)

For Research Use Only. Not for use in diagnostic procedures. Catalog #: MBS395657

Phospholipid-mediated signalling on neurons provokes diverse responses such as neurogenesis, pattern formation and neurite remodelling. A recently uncovered novel set of molecules in the mammalian brain, named plasticity-related genes (PRGs) mediate lipid… More details

$500 / 0.1 mg +1 FREE 8GB USB

Product Documentation

Sample Manual Insert View PDF

Testing Data View PDF

Certificate of Analysis (COA) View PDF

QC Report View PDF

Material Safety Data Sheet View PDF

Technical Datasheet View PDF

Protocol View PDF

Product Overview

Online Datasheet in PDF

Product Name

Lipid Phosphate Phosphatase Related Protein 4 (LPPR4), Polyclonal Antibody

Full Product Name

Lipid Phosphate Phosphatase Related Protein 4

Product Gene Name

anti-LPPR4 antibody

Product Synonym Names

LPPRP4; Plasticity Related Gene 1

Clonality

Polyclonal

Isotype

IgG

Host

Rabbit

Species Reactivity

Human

Form/Format

Provided as solution in phosphate buffered saline with 0.08% sodium azide

Purity/Purification

Ammonium Sulfate Precipitation

Preparation and Storage

Product should be stored at -20 degree C. Aliquot to avoid freeze/thaw cycles

Molecular Weight

82,983 Da

Chromosome Location

Chromosome: 1; NC_000001.10 (99729848..99775140). Location: 1p21.2

OMIM

607813

3D Structure

ModBase 3D Structure for Q7Z2D5

Immunogen

Synthetic peptide derived from the LPPRP4 protein

Positive Control

Human brain lysate

Product Categories/Family for anti-LPPR4 antibody

Polyclonal Antibody; Protein Phosphatases

Applications Tested/Suitable for anti-LPPR4 antibody

Western Blot (WB), ELISA (EIA)

Other Notes

Small volumes of anti-LPPR4 antibody vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.

Searchable Terms for LPPR4 purchase

MBS395657 is an antibody targeting LPPR4. Also known as Lipid Phosphate Phosphatase Related Protein 4. Reactive in Human. Host: Rabbit.

Additional Details

NCBI/Uniprot data below describe general gene information for LPPR4. It may not necessarily be applicable to this product.

NCBI GI #

261278368

NCBI GeneID

9890

NCBI Accession #

NP_001159724.1

UniProt Primary Accession #

Q7Z2D5

UniProt Secondary Accession #

O75043; Q5T9R9; Q86XQ5; Q8N3F1; Q96MP0; E7EPS1

UniProt Related Accession #

Q7Z2D5

GenBank Nucleotide #

NM_001166252.1

NCBI Official Full Name

lipid phosphate phosphatase-related protein type 4 isoform 2

NCBI Official Symbol

LPPR4

NCBI Official Synonym Symbols

LPR4; PHP1; PRG1; PRG-1; RP4-788L13.1

UniProt Protein Name

Lipid phosphate phosphatase-related protein type 4

UniProt Synonym Protein Names

Brain-specific phosphatidic acid phosphatase-like protein 1; Plasticity-related gene 1 protein

UniProt Gene Name

LPPR4

UniProt Synonym Gene Names

KIAA0455; PRG1; PRG-1

UniProt Entry Name

LPPR4_HUMAN

NCBI Protein Information

lipid phosphate phosphatase-related protein type 4; plasticity related gene 1; plasticity-related gene 1 protein; brain-specific phosphatidic acid phosphatase-like protein 1

NCBI Summary for LPPR4

The protein encoded by this gene belongs to the lipid phosphate phosphatase (LPP) family. LPPs catalyze the dephosphorylation of a number of bioactive lipid mediators that regulate a variety of cell functions. This protein is specifically expressed in neurons. It is located in the membranes of outgrowing axons and has been shown to be important for axonal outgrowth during development and regenerative sprouting. Alternatively spliced transcript variants encoding different isoforms have been found for this gene.[provided by RefSeq, Oct 2009]

UniProt Comments for LPPR4

Function: Hydrolyzes lysophosphatidic acid (LPA). Facilitates axonal outgrowth during development and regenerative sprouting. In the outgrowing axons acts as an ecto-enzyme and attenuates phospholipid-induced axon collapse in neurons and facilitates outgrowth in the hippocampus. Ref.1

Catalytic activity: A 1,2-diacylglycerol 3-phosphate + H2O = a 1,2-diacyl-sn-glycerol + phosphate.

Subcellular location: Membrane; Multi-pass membrane protein

Potential.

Tissue specificity: Specifically expressed in neurons. Ref.1

Sequence similarities: Belongs to the PA-phosphatase related phosphoesterase family.

Sequence caution: The sequence BAA32300.3 differs from that shown. Reason: Erroneous initiation. The sequence CAI22799.1 differs from that shown. Reason: Erroneous gene model prediction. The sequence EAW72991.1 differs from that shown. Reason: Erroneous gene model prediction.

Research Articles on LPPR4

1. Clinical trial of gene-disease association and gene-environment interaction. (HuGE Navigator)

Precautions

All of MyBioSource's Products are for scientific laboratory research purposes and are not for diagnostic, therapeutics, prophylactic or in vivo use. Through your purchase, you expressly represent and warrant to MyBioSource that you will properly test and use any Products purchased from MyBioSource in accordance with industry standards. MyBioSource and its authorized distributors reserve the right to refuse to process any order where we reasonably believe that the intended use will fall outside of our acceptable guidelines.

Disclaimer

While every efforts were made to ensure the accuracy of the information provided in this datasheet, MyBioSource will not be liable for any omissions or errors contained herein. MyBioSource reserves the right to make changes to this datasheet at any time without prior notice.

It is the responsibility of the customer to report product performance issues to MyBioSource within 30 days of receipt of the product. Please visit our Terms & Conditions page for more information.

Product Note

Select online data sheet information is drawn from bioinformatics databases, occasionally resulting in ambiguous or non-relevant product information. It is the responsibility of the customer to review, verify, and evaluate the information to make sure it matches their requirements before purchasing the kit. Our ELISA Kit assays are dynamic research tools and sometimes they may be updated and improved. If the format of this assay is important to you then please request the current manual or contact our technical support team with a presales inquiry before placing an order. We will confirm the current details of the assay. We cannot guarantee the sample manual posted online is the most current manual, it is intended to serve as an example only. Please refer to the instructions For Use provided with the assay kit for precise details.

Product PubMed Publications

Pathways associated with anti-LPPR4 antibody

Products by Pathway	Pathway Diagram
Triacylglycerol Biosynthesis Pathway antibodies	Triacylglycerol Biosynthesis Pathway Diagram

Diseases associated with anti-LPPR4 antibody

Disease Name	Pubmed Publications
Fatty Liver Antibodies	>1 publications with LPPR4 and Fatty Liver
Nervous System Diseases Antibodies	>1 publications with LPPR4 and Nervous System Diseases

Organs/Tissues associated with anti-LPPR4 antibody

Organ/Tissue Name	Pubmed Publications
Brain Antibodies	>1 publications with LPPR4 and Brain