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Ceramide Glycosyltransferase (UGCG) Antibody – Rabbit Polyclonal

For Research Use Only. Not for use in diagnostic procedures. Catalog #: MBS395805

May serve as a flippase as well as a glucosyltransferase that transfers glucose to ceramide. It Catalzes; UDP-glucose + N-acylsphingosine = UDP + D-glucosyl-N-acylsphingosine. Ceramide Glycosyltransferase is the first step in the Glycosphingolipid synthesis;… More details

$670 / 0.1 mg +1 FREE 8GB USB
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Testing Data View PDF
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Technical Datasheet View PDF
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Product Overview

Online Datasheet in PDF
Product Name
Ceramide Glycosyltransferase (UGCG), Polyclonal Antibody
Full Product Name
Ceramide Glycosyltransferase
Product Gene Name
Product Synonym Names
Glucosylceramide synthase; GCS; UDP glucose N-acylsphingosine D glucosyltransferase; GLCT-1; UDP glucose ceramide glucosyltransferase
Clonality
Polyclonal
Host
Rabbit
Species Reactivity
Human
Form/Format
Provided as solution in phosphate buffered saline with 0.08% sodium azide
Purity/Purification
Ammonium Sulfate Precipitation
Preparation and Storage
Product should be stored at -20 degree C. Aliquot to avoid freeze/thaw cycles
Molecular Weight
44856
Chromosome Location
Chromosome: 9; NC_000009.11 (114659206..114695439). Location: 9q31
OMIM
602874
3D Structure
ModBase 3D Structure for Q16739
Immunogen
Synthetic peptide derived from human ceramide glycosyltransferase protein.
Positive Control
Found in all tissues examined.
Applications Tested/Suitable for anti-UGCG antibody
Western Blot (WB), ELISA (EIA)

Western Blot/Blotting of anti-UGCG antibody

Western blot analysis using Ceramide Glycosyltransferase antibody (X1700P) on 7 ug of rat kidney lysate. Antibody used at 1 ug/ml. Visualized using Pierce West Femto substrate system. Secondary used at 1:75k dilution. Exposure for 60 seconds.
Rabbit Anti-UGCG Polyclonal Antibody – Cat# MBS395805

Other Notes

Small volumes of anti-UGCG antibody vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.

Searchable Terms for UGCG purchase

MBS395805 is an antibody targeting UGCG. Also known as Ceramide Glycosyltransferase. Reactive in Human. Host: Rabbit.

Additional Details

NCBI/Uniprot data below describe general gene information for UGCG. It may not necessarily be applicable to this product.

NCBI GI #
NCBI GeneID
NCBI Accession #
UniProt Primary Accession #
UniProt Secondary Accession #
UniProt Related Accession #
GenBank Nucleotide #
NCBI Official Full Name
ceramide glucosyltransferase
NCBI Official Synonym Full Names
UDP-glucose ceramide glucosyltransferase
NCBI Official Symbol
UGCG
NCBI Official Synonym Symbols
GCS; GLCT1
UniProt Protein Name
Ceramide glucosyltransferase
UniProt Synonym Protein Names
GLCT-1; Glucosylceramide synthase; GCS; UDP-glucose ceramide glucosyltransferase; UDP-glucose:N-acylsphingosine D-glucosyltransferase
UniProt Gene Name
UGCG
UniProt Synonym Gene Names
GCS
UniProt Entry Name
CEGT_HUMAN
NCBI Protein Information
ceramide glucosyltransferase; GLCT-1; glucosylceramide synthase; UDP-glucose:N-acylsphingosine D-glucosyltransferase

NCBI Summary for UGCG

Glycosphingolipids (GSLs) are a group of membrane components that contain lipid and sugar moieties. They are present in essentially all animal cells and are believed to have important roles in various cellular processes. UDP-glucose ceramide glucosyltransferase catalyzes the first glycosylation step in glycosphingolipid biosynthesis. The product, glucosylceramide, is the core structure of more than 300 GSLs. UGCG is widely expressed and transcription is upregulated during keratinocyte differentiation. [provided by RefSeq, Oct 2009]
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UniProt Comments for UGCG

Function: Catalyzes the first glycosylation step in glycosphingolipid biosynthesis, the transfer of glucose to ceramide. May also serve as a "flippase". Ref.1

Catalytic activity: UDP-glucose + N-acylsphingosine = UDP + D-glucosyl-N-acylsphingosine. Ref.1

Pathway: Lipid metabolism; sphingolipid metabolism.

Subcellular location: Golgi apparatus membrane; Multi-pass membrane protein

By similarity.

Tissue specificity: Found in all tissues examined. Ref.1

Sequence similarities: Belongs to the glycosyltransferase 2 family.
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Precautions

All of MyBioSource's Products are for scientific laboratory research purposes and are not for diagnostic, therapeutics, prophylactic or in vivo use. Through your purchase, you expressly represent and warrant to MyBioSource that you will properly test and use any Products purchased from MyBioSource in accordance with industry standards. MyBioSource and its authorized distributors reserve the right to refuse to process any order where we reasonably believe that the intended use will fall outside of our acceptable guidelines.

Disclaimer

While every efforts were made to ensure the accuracy of the information provided in this datasheet, MyBioSource will not be liable for any omissions or errors contained herein. MyBioSource reserves the right to make changes to this datasheet at any time without prior notice.

It is the responsibility of the customer to report product performance issues to MyBioSource within 30 days of receipt of the product. Please visit our Terms & Conditions page for more information.

Product Note

Select online data sheet information is drawn from bioinformatics databases, occasionally resulting in ambiguous or non-relevant product information. It is the responsibility of the customer to review, verify, and evaluate the information to make sure it matches their requirements before purchasing the kit. Our ELISA Kit assays are dynamic research tools and sometimes they may be updated and improved. If the format of this assay is important to you then please request the current manual or contact our technical support team with a presales inquiry before placing an order. We will confirm the current details of the assay. We cannot guarantee the sample manual posted online is the most current manual, it is intended to serve as an example only. Please refer to the instructions For Use provided with the assay kit for precise details.

Product PubMed Publications

Products associated with anti-UGCG antibody

 Reference Product  PubMed Publications
 ASAH1 antibody  >1 publications with UGCG and ASAH1
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