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ch-ALK2 Antibody – Sheep Polyclonal

For Research Use Only. Not for use in diagnostic procedures. Catalog #: MBS395823

Activin Receptor-Like Kinase 2 is a member of the superfamily of type I receptors for transforming growth factor- (TGF-). This receptor binds both activin and bone morphogenic proteins (BMPs). In mice, these receptors are expressed mainly in the… More details

$500 / 0.25 mg +1 FREE 8GB USB
Product Documentation
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Sample Manual Insert View PDF
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Testing Data View PDF
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Certificate of Analysis (COA) View PDF
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QC Report View PDF
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Material Safety Data Sheet View PDF
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Technical Datasheet View PDF
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Protocol View PDF

Product Overview

Online Datasheet in PDF
Product Name
ch-Alk2, Polyclonal Antibody
Full Product Name
ch-Alk2
Product Gene Name
Product Synonym Names
Activin Receptor-Like Kinase 2
Clonality
Polyclonal
Isotype
IgG
Host
Sheep
Species Reactivity
Chicken
Form/Format
Provided as solution in phosphate buffered saline with 0.08% sodium azide
Purity/Purification
Ammonium Sulfate Precipitation
Preparation and Storage
Product should be stored at -20 degree C. Aliquot to avoid freeze/thaw cycles
Molecular Weight
56,225 Da
Chromosome Location
Chromosome: 7; NC_006094.3 (35757877..35778048, complement). Location: chromosome: 7
3D Structure
ModBase 3D Structure for Q90ZK6
Immunogen
Recombinant protein derived from the extracellular domain of the chicken ALK2 protein. Protein shares significant homology with the mouse, rat and human sequences.
Applications Tested/Suitable for anti-ch-Alk2 antibody
Western Blot (WB)

Western Blot/Blotting of anti-ch-Alk2 antibody

Western blot using ALK-2 antibody on ALK-2 fusion protein.
Sheep Anti-ch-ALK2 Polyclonal Antibody – Cat# MBS395823

Other Notes

Small volumes of anti-ch-Alk2 antibody vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.

Searchable Terms for ch-Alk2 purchase

MBS395823 is an antibody targeting ch-Alk2. Reactive in Chicken. Host: Sheep.

Additional Details

NCBI/Uniprot data below describe general gene information for ch-Alk2. It may not necessarily be applicable to this product.

NCBI GI #
NCBI GeneID
NCBI Accession #
UniProt Primary Accession #
UniProt Secondary Accession #
UniProt Related Accession #
GenBank Nucleotide #
NCBI Official Full Name
activin receptor type-1
NCBI Official Synonym Full Names
activin A receptor, type I
NCBI Official Symbol
ACVR1
UniProt Protein Name
Activin receptor type-1
UniProt Synonym Protein Names
Activin receptor type I; Type I TGF B receptor
Protein Family
UniProt Gene Name
ACVR1
UniProt Entry Name
ACVR1_CHICK
NCBI Protein Information
activin receptor type-1; type I TGF B receptor; activin receptor type I

UniProt Comments for ch-Alk2

Function: On ligand binding, forms a receptor complex consisting of two type II and two type I transmembrane serine/threonine kinases. Type II receptors phosphorylate and activate type I receptors which autophosphorylate, then bind and activate SMAD transcriptional regulators. Receptor for activin

By similarity.

Catalytic activity: ATP + [receptor-protein] = ADP + [receptor-protein] phosphate.

Cofactor: Magnesium or manganese

By similarity.

Subcellular location: Membrane; Single-pass type I membrane protein

By similarity.

Sequence similarities: Belongs to the protein kinase superfamily. TKL Ser/Thr protein kinase family. TGFB receptor subfamily.Contains 1 GS domain.Contains 1 protein kinase domain.
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Precautions

All of MyBioSource's Products are for scientific laboratory research purposes and are not for diagnostic, therapeutics, prophylactic or in vivo use. Through your purchase, you expressly represent and warrant to MyBioSource that you will properly test and use any Products purchased from MyBioSource in accordance with industry standards. MyBioSource and its authorized distributors reserve the right to refuse to process any order where we reasonably believe that the intended use will fall outside of our acceptable guidelines.

Disclaimer

While every efforts were made to ensure the accuracy of the information provided in this datasheet, MyBioSource will not be liable for any omissions or errors contained herein. MyBioSource reserves the right to make changes to this datasheet at any time without prior notice.

It is the responsibility of the customer to report product performance issues to MyBioSource within 30 days of receipt of the product. Please visit our Terms & Conditions page for more information.

Product Note

Select online data sheet information is drawn from bioinformatics databases, occasionally resulting in ambiguous or non-relevant product information. It is the responsibility of the customer to review, verify, and evaluate the information to make sure it matches their requirements before purchasing the kit. Our ELISA Kit assays are dynamic research tools and sometimes they may be updated and improved. If the format of this assay is important to you then please request the current manual or contact our technical support team with a presales inquiry before placing an order. We will confirm the current details of the assay. We cannot guarantee the sample manual posted online is the most current manual, it is intended to serve as an example only. Please refer to the instructions For Use provided with the assay kit for precise details.

Product PubMed Publications

Products associated with anti-ch-Alk2 antibody

 Reference Product  PubMed Publications
 SMAD3 antibody  >5 publications with ch-Alk2 and SMAD3
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