• Call +1.858.633.0165 or Fax +1.858.633.0166 or Contact Us

Sphingosine 1 Phosphate 3 Receptor (EDG-3) Nt (EDG-3) Antibody – Rabbit Polyclonal

For Research Use Only. Not for use in diagnostic procedures. Catalog #: MBS396001

Endothelial cell differentation gene-3 (EDG3) belongs to a family of G-protein couple receptors whose ligands are lysophospholipids. The ligand for EDG3 is sphingosine-1-phosphate. There are 8 known members of the EDG receptor family. They have been… More details

$735 / 0.1 mg +1 FREE 8GB USB
Product Documentation
PDF
Sample Manual Insert View PDF
PDF
Testing Data View PDF
PDF
Certificate of Analysis (COA) View PDF
PDF
QC Report View PDF
PDF
Material Safety Data Sheet View PDF
PDF
Technical Datasheet View PDF
PDF
Protocol View PDF

Product Overview

Online Datasheet in PDF
Product Name
Sphingosine 1 Phosphate 3 Receptor (EDG-3) NT, Polyclonal Antibody
Full Product Name
Sphingosine 1 Phosphate 3 Receptor (EDG-3) NT
Product Gene Name
anti-EDG-3 antibody
Product Synonym Names
Endothelial cell differentiation gene 3 N-terminal; Sphingosine-1-Phosphate Receptor-3 (S1P3)
Clonality
Polyclonal
Host
Rabbit
Species Reactivity
Human
Form/Format
Provided as solution in phosphate buffered saline with 0.08% sodium azide
Purity/Purification
Ammonium Sulfate Precipitation
Preparation and Storage
Product should be stored at -20 degree C. Aliquot to avoid freeze/thaw cycles
Molecular Weight
42,250 Da
Chromosome Location
Chromosome: 9; NC_000009.11 (91606324..91620070). Location: 9q22.1-q22.2
OMIM
601965
3D Structure
ModBase 3D Structure for Q99500
Immunogen
Synthetic peptide derived from the N terminal of the EDG3 (S1P3) protein.
Positive Control
RH7777 cells transfected with EDG3 (S1P3) protein

Product Categories/Family for anti-EDG-3 antibody

Polyclonal Antibody; G Protein-Coupled Receptors
Applications Tested/Suitable for anti-EDG-3 antibody
Western Blot (WB)

Other Notes

Small volumes of anti-EDG-3 antibody vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.

Searchable Terms for EDG-3 purchase

MBS396001 is an antibody targeting EDG-3. Also known as Sphingosine 1 Phosphate 3 Receptor (EDG-3) NT. Reactive in Human. Host: Rabbit.

Additional Details

NCBI/Uniprot data below describe general gene information for EDG-3. It may not necessarily be applicable to this product.

NCBI GI #
38788193
NCBI GeneID
1903
NCBI Accession #
NP_005217.2
UniProt Primary Accession #
Q99500
UniProt Secondary Accession #
Q5SQD8; Q7Z5I2
UniProt Related Accession #
Q99500
GenBank Nucleotide #
NM_005226.3
NCBI Official Full Name
sphingosine 1-phosphate receptor 3
NCBI Official Synonym Full Names
sphingosine-1-phosphate receptor 3
NCBI Official Symbol
S1PR3
NCBI Official Synonym Symbols
EDG3; LPB3; S1P3; EDG-3
UniProt Protein Name
Sphingosine 1-phosphate receptor 3
UniProt Synonym Protein Names
Endothelial differentiation G-protein coupled receptor 3; Sphingosine 1-phosphate receptor Edg-3
UniProt Gene Name
S1PR3
UniProt Synonym Gene Names
EDG3; S1P receptor 3; S1P3
UniProt Entry Name
S1PR3_HUMAN
NCBI Protein Information
sphingosine 1-phosphate receptor 3; S1P receptor 3; S1P receptor EDG3; S1P receptor Edg-3; sphingosine 1-phosphate receptor Edg-3; endothelial differentiation G-protein coupled receptor 3; G protein-coupled receptor, endothelial differentiation gene-3; endothelial differentiation, sphingolipid G-protein-coupled receptor, 3

NCBI Summary for EDG-3

This gene encodes a member of the EDG family of receptors, which are G protein-coupled receptors. This protein has been identified as a functional receptor for sphingosine 1-phosphate and likely contributes to the regulation of angiogenesis and vascular endothelial cell function. [provided by RefSeq, Jul 2008]
Show more

UniProt Comments for EDG-3

Function: Receptor for the lysosphingolipid sphingosine 1-phosphate (S1P). S1P is a bioactive lysophospholipid that elicits diverse physiological effect on most types of cells and tissues. When expressed in rat HTC4 hepatoma cells, is capable of mediating S1P-induced cell proliferation and suppression of apoptosis. Ref.9

Subcellular location: Cell membrane; Multi-pass membrane protein.

Tissue specificity: Expressed in all tissues, but most abundantly in heart, placenta, kidney, and liver.

Sequence similarities: Belongs to the G-protein coupled receptor 1 family.
Show more

Research Articles on EDG-3

1. S1P3 receptors are detected in virtually all neurons in dorsal root ganglion and mediate pain behavior.

Precautions

All of MyBioSource's Products are for scientific laboratory research purposes and are not for diagnostic, therapeutics, prophylactic or in vivo use. Through your purchase, you expressly represent and warrant to MyBioSource that you will properly test and use any Products purchased from MyBioSource in accordance with industry standards. MyBioSource and its authorized distributors reserve the right to refuse to process any order where we reasonably believe that the intended use will fall outside of our acceptable guidelines.

Disclaimer

While every efforts were made to ensure the accuracy of the information provided in this datasheet, MyBioSource will not be liable for any omissions or errors contained herein. MyBioSource reserves the right to make changes to this datasheet at any time without prior notice.

It is the responsibility of the customer to report product performance issues to MyBioSource within 30 days of receipt of the product. Please visit our Terms & Conditions page for more information.

Product Note

Select online data sheet information is drawn from bioinformatics databases, occasionally resulting in ambiguous or non-relevant product information. It is the responsibility of the customer to review, verify, and evaluate the information to make sure it matches their requirements before purchasing the kit. Our ELISA Kit assays are dynamic research tools and sometimes they may be updated and improved. If the format of this assay is important to you then please request the current manual or contact our technical support team with a presales inquiry before placing an order. We will confirm the current details of the assay. We cannot guarantee the sample manual posted online is the most current manual, it is intended to serve as an example only. Please refer to the instructions For Use provided with the assay kit for precise details.

Product PubMed Publications

Products associated with anti-EDG-3 antibody

 Reference Product  PubMed Publications
 RAC1 antibody  >1 publications with EDG-3 and RAC1

Pathways associated with anti-EDG-3 antibody

 Products by Pathway  Pathway Diagram
 Class A/1 (Rhodopsin-like Receptors) Pathway antibodies  Class A/1 (Rhodopsin-like Receptors) Pathway Diagram
 G Alpha (i) Signalling Events Pathway antibodies  G Alpha (i) Signalling Events Pathway Diagram
 GPCR Downstream Signaling Pathway antibodies  GPCR Downstream Signaling Pathway Diagram
 GPCR Ligand Binding Pathway antibodies  GPCR Ligand Binding Pathway Diagram
 Lysosphingolipid And LPA Receptors Pathway antibodies  Lysosphingolipid And LPA Receptors Pathway Diagram
 Neuroactive Ligand-receptor Interaction Pathway antibodies  Neuroactive Ligand-receptor Interaction Pathway Diagram
 Neuroactive Ligand-receptor Interaction Pathway antibodies  Neuroactive Ligand-receptor Interaction Pathway Diagram
 S1P3 Pathway antibodies  S1P3 Pathway Diagram
 Signal Transduction Pathway antibodies  Signal Transduction Pathway Diagram
 Signal Transduction Of S1P Receptor Pathway antibodies  Signal Transduction Of S1P Receptor Pathway Diagram

Diseases associated with anti-EDG-3 antibody

 Disease Name  Pubmed Publications
 Inflammation Antibodies  >5 publications with EDG-3 and Inflammation
 Disease Models, Animal Antibodies  >3 publications with EDG-3 and Disease Models, Animal
 Fibrosis Antibodies  >2 publications with EDG-3 and Fibrosis
 Necrosis Antibodies  >2 publications with EDG-3 and Necrosis
 Congenital Abnormalities Antibodies  >1 publications with EDG-3 and Congenital Abnormalities
 Mammary Neoplasms, Animal Antibodies  >1 publications with EDG-3 and Mammary Neoplasms, Animal
 Heart Defects, Congenital Antibodies  >1 publications with EDG-3 and Heart Defects, Congenital
 Neoplasms Antibodies  >1 publications with EDG-3 and Neoplasms
 Neoplasms, Experimental Antibodies  >1 publications with EDG-3 and Neoplasms, Experimental
 Breast Neoplasms Antibodies  >1 publications with EDG-3 and Breast Neoplasms

Organs/Tissues associated with anti-EDG-3 antibody

 Organ/Tissue Name  Pubmed Publications
 Vascular Antibodies  >9 publications with EDG-3 and Vascular
 Blood Antibodies  >6 publications with EDG-3 and Blood
 Muscle Antibodies  >6 publications with EDG-3 and Muscle
 Lung Antibodies  >5 publications with EDG-3 and Lung
 Liver Antibodies  >2 publications with EDG-3 and Liver
 Heart Antibodies  >2 publications with EDG-3 and Heart
 Uterus Antibodies  >2 publications with EDG-3 and Uterus
 Embryonic Tissue Antibodies  >2 publications with EDG-3 and Embryonic Tissue
 Bone Antibodies  >1 publications with EDG-3 and Bone
 Skin Antibodies  >1 publications with EDG-3 and Skin
Request a Quote

Please fill out the form below and our representative will get back to you shortly.

MBS000000
Contact Us

Please fill out the form below and our representative will get back to you shortly.

MBS000000