Lung Carcinoma Cluster 1 Antibody – Mouse

The MOC-1 antibody belongs to cluster 1 antibodies which react with neuroendocrine tissue (N-CAM) and in the lung typically detect SCLC and carcinoids. On the VI. International Workshop on Leukocyte Differentiation (Kobe 1996) this antibody has been designed as CD56, which is a known marker for natural killer cells (NK-cells). Lung cancer is a heterogeneous disease which may be characterized by five histopathological criteria. A distinction is drawn between squamous epithelial carcinoma, adenocarcinoma, large cell carcinoma, adenosquamous carcinoma and small cell lung carcinoma (SCLC). The first four in this line are cited as "non-SCLC" in literature. A number of antibodies have been used for the characterization and clustering of lung carcinoma during the 1. International Workshop on Small Cell Lung Cancer Antigens, London 1987. Cluster 1 membrane protein 125-145 kDa.

1. De Leij L., Poppema S., Nulend J. K., Ter Haar A., Schwander E., Ebbens F., Postmus P. E., and The T. H. (1985) Neuroendocrine differentiation antigen on human lung carcinoma and Kulchitski Cells. Cancer Res. 45; 2192-2200. 2. Berendsen H.H., et al. (1988) Detection of small cell lung cancer metastases in bone marrow aspirates using monoclonal antibodies directed against neuroendocrine differentiation antigen. J. Clin. Pathol. 14; 273-276. 3. Ruitenbeek T., et al. (1994) Immunocytology of body cavity fluids. Arch. Pathol. Lab. Med. 118; 265-269.

Small volumes of anti-Lung carcinoma Cluster 1 antibody vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.

MBS397268 is an antibody targeting Lung carcinoma Cluster 1. Also known as Lung carcinoma Cluster 1, N-CAM (MOC-1). Reactive in Human, Cattle. Host: Mouse.