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Neurofilaments Antibody – Mouse

For Research Use Only. Not for use in diagnostic procedures. Catalog #: MBS397290

This antibody may also stain phaeochromocytoma and medullary adrenal cells. Neurofilament proteins are characteristic intermediary filaments of neurons. They are divided into three classes of molecular weights: 70, 160 and 200 kDa. As well central as… More details

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Product Overview

Product Name
Neurofilaments, Antibody
Full Product Name
Neurofilaments 70/200 kDa
Isotype
IgG1
Clone Number
2F11
Host
Mouse
Species Reactivity
Human, Cattle, Dog, Horse, Mouse, Pig, Rat
Form/Format
Solution in stabilizing phosphate buffer pH 7.3. Contains 0.09 % sodium azide.
Preparation and Storage
Store at 2-8 degree C.
Immunogen
Purified neurofilament proteins from human brain
Positive Control
Nerve tissue
Incubation Time
60 min at RT
Pre-Treatment
No protease pre-treatment required! Blocking of endogenous biotin and alkaline phosphatase is recommended, if avidin/biotin systems are used.
Applications Tested/Suitable for anti-Neurofilaments antibody
Immunohistochemistry (IHC) Formalin/Paraffin, Immunoblotting (IB)
Application Notes for anti-Neurofilaments antibody
Dilution: 1:10-1:50

Product References and Citations for anti-Neurofilaments antibody

1. Osborn M., Altmannsberger M., Shaw G., Schauer A., Weber K. (1982) Various sympathetic derived human tumors differ in neurofilament expression. Use in Diagnosis of neuroblastoma, ganglioneuroblastoma and pheochromocytoma. Virchows Arch. Cell Pathol. 40; 141-156. 2. Alfonsi F., Darmon M., Forest N., and Paulin D. (1983) Intermediate sized filaments as markers of neuronal differentiation in the role of cell interaction in early neurogenesis. In: Plenum Publishing Corporation A.M. Duprat, A. Kato, and M. Weber eds. pp 157-176. 3. Osborn M., and Weber K. (1983) Biology of disease tumor diagnosis by intermediate filament typing. Lab. Invest. 48; 372-394. 4. Klück P., et al. (1984) Hirschsprung disease studied with monoclonal anti neurofilament antibodies on tissue sections. The Lancet, March 24, 652-653. 5. Osborn M., Dirk T., Käser H., Weber K., and Altmannsberger M. (1986) Immunohistochemical localization of neurofilaments and neuron-specific enolase in 29 cases of neuroblastoma. Am. J. Pathol. 122; 433-442.

Other Notes

Small volumes of anti-Neurofilaments antibody vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.

Searchable Terms for Neurofilaments purchase

MBS397290 is an antibody targeting Neurofilaments. Also known as Neurofilaments 70/200 kDa. Reactive in Human, Cattle, Dog, Horse, Mouse, Pig, Rat. Host: Mouse.
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