• Call +1.858.633.0165 or Fax +1.858.633.0166 or Contact Us

COVID 19 Spike S1 Coronavirus (COVID-19) Active Protein

For Research Use Only. Not for use in diagnostic procedures. Catalog #: MBS398011

The spike (S) glycoprotein of SARS-CoV-2, which is highly exposed on the viral surface, plays a major role in inducing neutralizing antibody, T cell responses and protective immunity. The S protein contains two subunits: S1 and S2 cleaved by furin in host… More details

$555 / 0.1 mg +1 FREE 8GB USB
Product Documentation
PDF
Sample Manual Insert View PDF
PDF
Testing Data View PDF
PDF
Certificate of Analysis (COA) View PDF
PDF
QC Report View PDF
PDF
Material Safety Data Sheet View PDF
PDF
Technical Datasheet View PDF
PDF
Protocol View PDF

Product Overview

Online Datasheet in PDF
Product Name
COVID 19 Spike S1 Coronavirus (COVID-19), Active Protein
Full Product Name
SARS-CoV-2 Spike S1 protein
Product Gene Name
COVID-19 active protein
Product Synonym Gene Name
2019-nCoV; SARS-CoV-2; SARS coronavirus 2 proteome; COVID19; SARS-CoV2
Product Synonym Names
2019 Novel Coronavirus; Coronavirus; CoV; COVID-19 virus; HCoV-2; Human Coronavirus 2019; SARS2; SARS-CoV-2; Severe acute respiratory syndrome coronavirus 2; Spike S1
Host
HEK293 Cell
Purity/Purification
>95%
Preparation and Storage
Lyophilized from sterile PBS, pH 7.4. Lyophilized protein can be stored at 2°C to 8°C for short-term (<1 week), and at -20°C to -80° for long term.
For reconstitution, add 100 ul of deionized water, mix gently and incubate the reconstituted product for 10 minutes at room temperature prior to use, Reconstituted protein, if not being used immediately, should be aliquoted and kept at -20°C to 80°C Avoid repeated freeze-thaw cycles.
Active Protein Note
Protein activity can be an ambiguous term. Please refer to the data sheet or inquire with Technical Support to determine the definition of activity for this product.
Tag Information
His at C-terminus
Endotoxin
<5 EU/mg, determined by the LAL method
Bioactivity
Strong binding ability with human ACE2 protein and binding capacity to a human anti-S1 monoclonal antibody (determined by ELISA).
Antigenicity
Antigenicity validated in covid positive samples via ELISA test by coating SARS-CoV-2 S1 as capture antigen.
Dry Ice Shipment
Extra charge fee may add to your shipping cost as dry ice is required to ship this product.
Applications Tested/Suitable for COVID-19 active protein
Functional Test, Immunoassay for detection of anti-S1 antibody in human blood

SDS-PAGE of COVID-19 active protein

The recombinant SARS-CoV-2 Spike S1 Protein (YP_009724390.1) (Val16-Arg685) with C-terminal His-tag consists of 681 amino acids. Its predicted molecular mass of 77 kDa. The apparent molecular mass of S1 in SDS-PAGE is around 120 kDa, probably due to glycosylation.
COVID-19 Active Protein – Cat# MBS398011

Testing Data of COVID-19 active protein

COVID-19 Active Protein, Testing Data – Cat# MBS398011

Testing Data of COVID-19 active protein

COVID-19 Active Protein, Testing Data – Cat# MBS398011

Product References and Citations for COVID-19 active protein

1. Shajahan A, et al. (2020) Deducing the N- and O-glycosylation profile of the spike protein of novel coronavirus SARS-CoV-2. bioRxiv, https://doi.org/10.1101/2020.04.01.020966.
2. Walls, A C, et al. (2020) Structure, Function, and Antigenicity of the SARS-CoV-2 Spike Glycoprotein. Cell, 181(2), 281-292.e6. https://doi.org/10.1016/j.cell.2020.02.058.

Other Notes

Small volumes of COVID-19 active protein vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.

Searchable Terms for COVID-19 purchase

MBS398011 is an active protein targeting COVID-19. Also known as SARS-CoV-2 Spike S1 protein. Host: HEK293 Cell.

Additional Details

NCBI/Uniprot data below describe general gene information for COVID-19. It may not necessarily be applicable to this product.

NCBI Accession #
YP_009724390.1

Precautions

All of MyBioSource's Products are for scientific laboratory research purposes and are not for diagnostic, therapeutics, prophylactic or in vivo use. Through your purchase, you expressly represent and warrant to MyBioSource that you will properly test and use any Products purchased from MyBioSource in accordance with industry standards. MyBioSource and its authorized distributors reserve the right to refuse to process any order where we reasonably believe that the intended use will fall outside of our acceptable guidelines.

Disclaimer

While every efforts were made to ensure the accuracy of the information provided in this datasheet, MyBioSource will not be liable for any omissions or errors contained herein. MyBioSource reserves the right to make changes to this datasheet at any time without prior notice.

It is the responsibility of the customer to report product performance issues to MyBioSource within 30 days of receipt of the product. Please visit our Terms & Conditions page for more information.

Product Note

Select online data sheet information is drawn from bioinformatics databases, occasionally resulting in ambiguous or non-relevant product information. It is the responsibility of the customer to review, verify, and evaluate the information to make sure it matches their requirements before purchasing the kit. Our ELISA Kit assays are dynamic research tools and sometimes they may be updated and improved. If the format of this assay is important to you then please request the current manual or contact our technical support team with a presales inquiry before placing an order. We will confirm the current details of the assay. We cannot guarantee the sample manual posted online is the most current manual, it is intended to serve as an example only. Please refer to the instructions For Use provided with the assay kit for precise details.
Request a Quote

Please fill out the form below and our representative will get back to you shortly.

MBS000000
Contact Us

Please fill out the form below and our representative will get back to you shortly.

MBS000000