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Fibroblast Growth Factor 21 (FGF-21) Antibody – Rabbit Polyclonal

For Research Use Only. Not for use in diagnostic procedures. Catalog #: MBS398034

Fibroblast growth factor 21 (FGF-21) is a novel protein that has been implicated in the regulation of lipid and glucose metabolism under fasting and ketotic conditions. In murine models, FGF-21 is predominantly expressed in liver, but it also expressed in… More details

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Product Overview

Product Name
Fibroblast growth factor 21 (FGF-21), Polyclonal Antibody
Full Product Name
Fibroblast growth factor 21 (FGF-21): Mouse, Rabbit polyclonal (Antibody)
Product Gene Name
Product Synonym Names
FGF-21; Polyclonal Antibody against Mouse FGF - 21
Clonality
Polyclonal
Isotype
Rabbit IgG
Host
Rabbit
Species Reactivity
Mouse
Form/Format
Solution in PBS
Purity/Purification
Rabbit specific IgG was purified by mouse FGF-21 affinity chromatography
Specificity
The antibody detects circular mouse FGF-21.
Preparation and Storage
Store at -20 degree C. For long-term storage, aliquot and freeze at -70 degree C. Avoid repeated freeze/defrost cycles.
Immunogen
Recombinant full-length mouse FGF-21 expressed in E Coli
Applications Tested/Suitable for anti-FGF-21 antibody
Western Blot (WB), ELISA (EIA)
Application Notes for anti-FGF-21 antibody
ELISA: This antibody can be used at 2ug/mL with theappropriate secondary reagents to detect mouse FGF-21.
WB: This antibody can be used at0.2ug/mL~0.5ug/mL with the appropriate secondary reagentsto detect mouse FGF-21.
Immunoprecipitation and immunocytochemistry are not tested.

Western Blot (WB) of anti-FGF-21 antibody

Western blot analysis of FGF21 in10ug non FGF21 expressing celllysate (Lane 1,3) and FGF21expressing cell lysate (Lane 2,4)using anti-FGF21 followed by goatanti-rabbit antibody. (The figure isfrom Prof. Cheah's lab, HKU.)
Rabbit Anti-FGF-21 Polyclonal Antibody – Cat# MBS398034

Product References and Citations for anti-FGF-21 antibody

1. Stressed Liver and Muscle Call on Adipocytes with FGF21. Luo Y, McKeehan WL. Front Endocrinol 2013 18;4:194
2. Fibroblast growth factor 21 as an emerging metabolic regulator: clinical perspectives. Woo YC, Xu A, Wang Y, Lam KS. Clin Endocrinol (Oxf). 2013 Apr;78(4):489-96

[1] Kharitonenkov A, Shiyanova TL, et al. (2005) J Clin Invest; 115: 1627- 1635
[2] Badman MK, Pissios P, et al. (2007) Cell Metab; 5: 426- 437
[3] Nishimura T, Nakatake Y, et al. (2000) Biochim Biophys Acta; 1492: 203- 206
[4] Kurosu H, Choi M, et al. (2007) J Biol Chem; 282: 26687- 26695
[5] Kharitonenkov A, Wroblewski VJ, et al. (2007) Endocrinology;148:774-81
[6] Chavez AO, Molina-Carrion M, et al. (2009) Diabetes Care; 32:1542-6.

Other Notes

Small volumes of anti-FGF-21 antibody vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.

Searchable Terms for FGF-21 purchase

MBS398034 is an antibody targeting FGF-21. Also known as Fibroblast growth factor 21 (FGF-21): Mouse, Rabbit polyclonal (Antibody). Reactive in Mouse. Host: Rabbit.

Additional Details

NCBI/Uniprot data below describe general gene information for FGF-21. It may not necessarily be applicable to this product.

NCBI GI #
NCBI GeneID
GenBank Nucleotide #
NCBI Official Full Name
fibroblast growth factor 21
NCBI Official Symbol
FGF21
NCBI Protein Information
fibroblast growth factor 21

Precautions

All of MyBioSource's Products are for scientific laboratory research purposes and are not for diagnostic, therapeutics, prophylactic or in vivo use. Through your purchase, you expressly represent and warrant to MyBioSource that you will properly test and use any Products purchased from MyBioSource in accordance with industry standards. MyBioSource and its authorized distributors reserve the right to refuse to process any order where we reasonably believe that the intended use will fall outside of our acceptable guidelines.

Disclaimer

While every efforts were made to ensure the accuracy of the information provided in this datasheet, MyBioSource will not be liable for any omissions or errors contained herein. MyBioSource reserves the right to make changes to this datasheet at any time without prior notice.

It is the responsibility of the customer to report product performance issues to MyBioSource within 30 days of receipt of the product. Please visit our Terms & Conditions page for more information.

Product Note

Select online data sheet information is drawn from bioinformatics databases, occasionally resulting in ambiguous or non-relevant product information. It is the responsibility of the customer to review, verify, and evaluate the information to make sure it matches their requirements before purchasing the kit. Our ELISA Kit assays are dynamic research tools and sometimes they may be updated and improved. If the format of this assay is important to you then please request the current manual or contact our technical support team with a presales inquiry before placing an order. We will confirm the current details of the assay. We cannot guarantee the sample manual posted online is the most current manual, it is intended to serve as an example only. Please refer to the instructions For Use provided with the assay kit for precise details.
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