Plasminogen Activator Inhibitor Type-1 (PAI-1) ELISA Kit for Human

Plasminogen activator inhibitor-1 (PAI-1) is a prothrombotic plasma protein secreted by endothelial tissue which has long been implicated in CVD. Additional literature has recently implicated it in the pathogenesis of other diseases ranging from cancer to major depressive disorders.Prognostic and predictive biomarkers in breast cancer: Past, present and future.

Nicolini A, Ferrari P, Duffy MJ.Semin Cancer Biol. 2017 Sep 4. pii: S1044-579X(17)30052-4.Plasminogen Activator Inhibitor-1 Is a Marker and a Mediator of Senescence.
Vaughan DE, Rai R, Khan SS, Eren M, Ghosh AK.
Arterioscler Thromb Vasc Biol. 2017 Aug;37(8):1446-1452.
The contribution of different adipose tissue depots to plasma plasminogen activator inhibitor-1(PAI-1) levels.Barnard SA, Pieters M, De Lange Z.Blood Rev. 2016 Nov;30(6):421-429.

Small volumes of PAI-1 elisa kit vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.

MBS398050 is a ready-to-use microwell, strip-or-full plate ELISA (enzyme-linked immunosorbent assay) Kit for analyzing the presence of the plasminogen activator inhibitor type-1 (PAI-1) ELISA Kit target analytes in biological samples. The concentration gradients of the kit standards or positive controls render a theoretical kit detection range in biological research samples containing PAI-1. The ELISA analytical biochemical technique of the MBS398050 kit is based on PAI-1 antibody-PAI-1 antigen interactions (immunosorbency) and an HRP colorimetric detection system to detect PAI-1 antigen targets in samples. The ELISA Kit is designed to detect native, not recombinant, PAI-1. Appropriate sample types may include undiluted body fluids and/or tissue homogenates, secretions. Quality control assays assessing reproducibility identified the intra-assay CV (%) and inter-assay CV(%).