LCN2 Recombinant Protein – Cat# MBS398085

Lipocalin-2 (LCN2) Recombinant Protein

Name: LCN2 Recombinant Protein; Lipocalin-2; Research Grade; MyBioSource
Brand: MyBioSource
SKU: MBS398085
Price: 415 USD
Availability: InStock
Rating: 5 (10 reviews)

For Research Use Only. Not for use in diagnostic procedures. Catalog #: MBS398085

Lipocalin-2 (LCN2), also known as neutrophil gelatinase-associated lipocalin (NGAL), 24p3, or neutrophil lipocalin (NL), is a 25-kDa secretory glycoprotein which isexpressed in liver, lung, kidney, adipocytes, activated neutrophils, and macrophages. LCN2 has… More details

$415 / 0.1 mg +1 FREE 8GB USB

Product Documentation

Sample Manual Insert View PDF

Testing Data View PDF

Certificate of Analysis (COA) View PDF

QC Report View PDF

Material Safety Data Sheet View PDF

Technical Datasheet View PDF

Protocol View PDF

Product Overview

Online Datasheet in PDF

Product Name

Lipocalin-2 (LCN2), Recombinant Protein

Full Product Name

Lipocalin-2: Mouse (Recombinant protein)

Product Gene Name

LCN2 recombinant protein

Product Synonym Gene Name

24p3, MSFI, NGAL, LCN2

Product Synonym Names

Lipocalin 2; Recombinant Mouse Lipocalin-2 (NGAL)

Sequence

MSYYHHHHHH DYDIPTTENL YFQGAMGS QDSTQNLIPA PSLLTVPLQP DFRSDQFRGR WYVVGLAGNA VQKKTEGSFT MYSTIYELQE NNSYNTSIL VRDQDQGCRY WIRTFVPSSR AGQFTLGNMH RYPQVQSYNV AVATTDYNQF AMVFFRKTSE NKQYFKITLY GRTKELSPEL KERFTRFAKS LGLKDDNIIF SVPTDQCIDN

Host

E Coli

Form/Format

Lyophilized in 1mg/mL in PBS

Purity/Purification

>95%; SDS PAGE to determine purity of the protein

Preparation and Storage

Store lyophilized protein at -20 degree C. Aliquot reconstituted protein and store at -80 degree C. Avoid repeated freezing /thawing cycles.

Molecular Weight

24.2kDa

Species

Mouse

Tag

His Tag

Reconstitution

Add deionized water to prepare a working stock solution of approximately 1mg/mL and let the lyophilized pellet dissolve completely.

Quality Control Test

BCA to determine quantity of the protein.

Applications Tested/Suitable for LCN2 recombinant protein

ELISA (EIA), Western Blot (WB)

Product References and Citations for LCN2 recombinant protein

1. A emerging clinical and experimental evidence for the role of lipocalin-2 in metabolic syndrome. Jang Y, Lee JH, Wang Y, Sweeney G. Clin Exp Pharmacol Physiol. 2012 Feb;39(2):194-9
2. The multifaceted roles of neutrophil gelatinase associated lipocalin (NGAL) in inflammation and cancer. Chakraborty S, Kaur S, Guha S, Batra SK. Biochim Biophys Acta. 2012 Aug;1826(1):129-69.

Other Notes

Small volumes of LCN2 recombinant protein vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.

Searchable Terms for LCN2 purchase

MBS398085 is a recombinant protein targeting LCN2. Also known as Lipocalin-2: Mouse (Recombinant protein). Host: E Coli.

Additional Details

NCBI/Uniprot data below describe general gene information for LCN2. It may not necessarily be applicable to this product.

NCBI GI #

21619839

NCBI GeneID

3934

UniProt Related Accession #

P80188

NCBI Official Full Name

Lipocalin 2

NCBI Official Synonym Full Names

lipocalin 2

NCBI Official Symbol

LCN2

NCBI Official Synonym Symbols

p25; 24p3; MSFI; NGAL

Protein Family

Neutrophil gelatinase-associated lipocalin

NCBI Protein Information

neutrophil gelatinase-associated lipocalin

NCBI Summary for LCN2

This gene encodes a protein that belongs to the lipocalin family. Members of this family transport small hydrophobic molecules such as lipids, steroid hormones and retinoids. The protein encoded by this gene is a neutrophil gelatinase-associated lipocalin and plays a role in innate immunity by limiting bacterial growth as a result of sequestering iron-containing siderophores. The presence of this protein in blood and urine is an early biomarker of acute kidney injury. This protein is thought to be be involved in multiple cellular processes, including maintenance of skin homeostasis, and suppression of invasiveness and metastasis. Mice lacking this gene are more susceptible to bacterial infection than wild type mice. [provided by RefSeq, Sep 2015]

Research Articles on LCN2

1. The accumulation of NGAL in supernatants in vitro and in the urine of Chronic Allograft Nephropathy patients was concurrent with loss of Arl13b, a specific ciliary protein. The findings of this study propose that increased NGAL urinary concentrations are directly linked to deciliation of the renal epithelial cells as a result of injury.

Precautions

All of MyBioSource's Products are for scientific laboratory research purposes and are not for diagnostic, therapeutics, prophylactic or in vivo use. Through your purchase, you expressly represent and warrant to MyBioSource that you will properly test and use any Products purchased from MyBioSource in accordance with industry standards. MyBioSource and its authorized distributors reserve the right to refuse to process any order where we reasonably believe that the intended use will fall outside of our acceptable guidelines.

Disclaimer

While every efforts were made to ensure the accuracy of the information provided in this datasheet, MyBioSource will not be liable for any omissions or errors contained herein. MyBioSource reserves the right to make changes to this datasheet at any time without prior notice.

It is the responsibility of the customer to report product performance issues to MyBioSource within 30 days of receipt of the product. Please visit our Terms & Conditions page for more information.

Product Note

Select online data sheet information is drawn from bioinformatics databases, occasionally resulting in ambiguous or non-relevant product information. It is the responsibility of the customer to review, verify, and evaluate the information to make sure it matches their requirements before purchasing the kit. Our ELISA Kit assays are dynamic research tools and sometimes they may be updated and improved. If the format of this assay is important to you then please request the current manual or contact our technical support team with a presales inquiry before placing an order. We will confirm the current details of the assay. We cannot guarantee the sample manual posted online is the most current manual, it is intended to serve as an example only. Please refer to the instructions For Use provided with the assay kit for precise details.

Product PubMed Publications

Products associated with LCN2 recombinant protein

Reference Product	PubMed Publications
EGFR recombinant protein	>59 publications with LCN2 and EGFR
MMP9 recombinant protein	>15 publications with LCN2 and MMP9
HMOX1 recombinant protein	>11 publications with LCN2 and HMOX1
PPARG recombinant protein	>6 publications with LCN2 and PPARG
LIF recombinant protein	>2 publications with LCN2 and LIF
GFAP recombinant protein	>2 publications with LCN2 and GFAP

Diseases associated with LCN2 recombinant protein

Disease Name	Pubmed Publications
Kidney Diseases Antibodies	>493 publications with LCN2 and Kidney Diseases
Acute Kidney Injury Antibodies	>446 publications with LCN2 and Acute Kidney Injury
Renal Insufficiency Antibodies	>353 publications with LCN2 and Renal Insufficiency
Inflammation Antibodies	>231 publications with LCN2 and Inflammation
Neoplasms Antibodies	>178 publications with LCN2 and Neoplasms
Cardiovascular Diseases Antibodies	>167 publications with LCN2 and Cardiovascular Diseases
Heart Diseases Antibodies	>86 publications with LCN2 and Heart Diseases
Necrosis Antibodies	>80 publications with LCN2 and Necrosis
Disease Models, Animal Antibodies	>69 publications with LCN2 and Disease Models, Animal
Proteinuria Antibodies	>68 publications with LCN2 and Proteinuria

Organs/Tissues associated with LCN2 recombinant protein

Organ/Tissue Name	Pubmed Publications
Blood Antibodies	>632 publications with LCN2 and Blood
Kidney Antibodies	>564 publications with LCN2 and Kidney
Liver Antibodies	>111 publications with LCN2 and Liver
Lung Antibodies	>64 publications with LCN2 and Lung
Bone Antibodies	>33 publications with LCN2 and Bone
Muscle Antibodies	>30 publications with LCN2 and Muscle
Connective Tissue Antibodies	>28 publications with LCN2 and Connective Tissue
Bone Marrow Antibodies	>25 publications with LCN2 and Bone Marrow
Intestine Antibodies	>21 publications with LCN2 and Intestine
Uterus Antibodies	>19 publications with LCN2 and Uterus