Bgrowth Hormone (bGH) Active Protein

Name: bGH Active Protein; Bgrowth Hormone; Research Grade; MyBioSource
Brand: MyBioSource
SKU: MBS143497
Price: 250 USD
Availability: InStock
Rating: 5 (10 reviews)

For Research Use Only. Not for use in diagnostic procedures. Catalog #: MBS143497

Growth Hormone Bovine Recombinant produced in E Coli is a single, non-glycosylated polypeptide chain containing 191 amino acids and having a molecular mass of 21.8 kDa. The GH Bovine Recombinant is purified by proprietary chromatographic techniques. More details

$250 / 0.02 mg +1 FREE 8GB USB

Product Documentation

Sample Manual Insert View PDF

Testing Data View PDF

Certificate of Analysis (COA) View PDF

QC Report View PDF

Material Safety Data Sheet View PDF

Technical Datasheet View PDF

Protocol View PDF

Product Overview

Online Datasheet in PDF

Product Name

BGrowth Hormone (bGH), Active Protein

Full Product Name

Recombinant Bovine Growth Hormone

Product Gene Name

bGH active protein

Product Synonym Names

GH Bovine; Growth Hormone Bovine Recombinant; BGH; BST; rBGH; rBST; Bovine Somatotropin; Bovine GH; Growth hormone; GH1

Host

E Coli

Form/Format

Sterile Filtered White lyophilized (freeze-dried) powder.
The Bovine Growth Hormone protein was lyophilized from a concentrated (1mg/ml) solution with 4.5mM NaHCO₃ adjusted to pH 8-9.

Purity/Purification

Greater than 98.0% as determined by: (a) Analysis by SEC-HPLC. (b) Analysis by SDS-PAGE.

Concentration

1mg/ml (lot specific)

Preparation and Storage

Lyophilized Bovine Growth Hormone although stable at room temperature for 3 weeks, should be stored desiccated below -18°C.
Upon reconstitution GH Bovine should be stored at 4°C between 2-7 days and for future use below -18°C.
For long term storage it is recommended to add a carrier protein (0.1% HSA or BSA).
Please prevent freeze-thaw cycles.

3D Structure

ModBase 3D Structure for P01246

Active Protein Note

Protein activity can be an ambiguous term. Please refer to the data sheet or inquire with Technical Support to determine the definition of activity for this product.

Protein Content

UV spectroscopy at 280 nm using the absorbency value of 0.63 as the extinction coefficient for a 0.1% (1mg/ml) solution. This value is calculated by the PC GENE computer analysis program of protein sequences.

Solubility

It is recommended to reconstitute the lyophilized Bovine Growth Hormone in 0.4% NaHCO₃ or sterile 18M Omega-cm H₂O not less than 100 ug/ml, which can then be further diluted to other aqueous solutions.

Biological Activity

The activity as determined by the PDFP13B9 cells stably transfected with rabbit GH receptors. Bovine GH is also capable of forming a 1:2 complex with the recombinant ovine growth hormone receptor extracellular domain (ECD).

Amino Acid Sequence

1 - afpamslsgl fanavlraqh lhqlaadtfk efertyipeg qrysiqntqv
51 - afcfsetmpa ptgkneaqqk sdlellrisl lliqswlgpl qflsrvftns
101 - lvfgtsdrvy eklkdleegi lalmreledg tprrgqilkq tydkfdtnmr
151 - sddallknyg llscfrkdlh ktetylrvmk crrfgeasca f

Product Categories/Family for bGH active protein

Cytokines and Growth Factors; Growth Factors; Growth Hormone

Other Notes

Small volumes of bGH active protein vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.

Searchable Terms for bGH purchase

MBS143497 is an active protein targeting bGH. Also known as Recombinant Bovine Growth Hormone. Host: E Coli.

Additional Details

NCBI/Uniprot data below describe general gene information for bGH. It may not necessarily be applicable to this product.

NCBI GI #

30794288

NCBI GeneID

280804

NCBI Accession #

NP_851339.1

UniProt Primary Accession #

P01246

UniProt Secondary Accession #

Q28117; Q3LS73; A4GX96

UniProt Related Accession #

P01246

GenBank Nucleotide #

NM_180996.1

NCBI Official Full Name

somatotropin

NCBI Official Symbol

GH1

NCBI Official Synonym Symbols

UniProt Protein Name

Somatotropin

UniProt Synonym Protein Names

Growth hormone

UniProt Gene Name

GH1

UniProt Synonym Gene Names

UniProt Entry Name

SOMA_BOVIN

NCBI Protein Information

somatotropin

UniProt Comments for bGH

Plays an important role in growth control. Its major role in stimulating body growth is to stimulate the liver and other tissues to secrete IGF-1. It stimulates both the differentiation and proliferation of myoblasts. It also stimulates amino acid uptake and protein synthesis in muscle and other tissues.

Research Articles on bGH

1. Whereas only moderate structural changes were observed with up-regulation of GH/IGF-I axis, disruption of the GH receptor had pronounced effects upon tendon ultra-structure.

Precautions

All of MyBioSource's Products are for scientific laboratory research purposes and are not for diagnostic, therapeutics, prophylactic or in vivo use. Through your purchase, you expressly represent and warrant to MyBioSource that you will properly test and use any Products purchased from MyBioSource in accordance with industry standards. MyBioSource and its authorized distributors reserve the right to refuse to process any order where we reasonably believe that the intended use will fall outside of our acceptable guidelines.

Disclaimer

While every efforts were made to ensure the accuracy of the information provided in this datasheet, MyBioSource will not be liable for any omissions or errors contained herein. MyBioSource reserves the right to make changes to this datasheet at any time without prior notice.

It is the responsibility of the customer to report product performance issues to MyBioSource within 30 days of receipt of the product. Please visit our Terms & Conditions page for more information.

Product Note

Select online data sheet information is drawn from bioinformatics databases, occasionally resulting in ambiguous or non-relevant product information. It is the responsibility of the customer to review, verify, and evaluate the information to make sure it matches their requirements before purchasing the kit. Our ELISA Kit assays are dynamic research tools and sometimes they may be updated and improved. If the format of this assay is important to you then please request the current manual or contact our technical support team with a presales inquiry before placing an order. We will confirm the current details of the assay. We cannot guarantee the sample manual posted online is the most current manual, it is intended to serve as an example only. Please refer to the instructions For Use provided with the assay kit for precise details.

Product PubMed Publications

Pathways associated with bGH active protein

Products by Pathway	Pathway Diagram
Cytokine Signaling In Immune System Pathway antibodies	Cytokine Signaling In Immune System Pathway Diagram
Growth Hormone Receptor Signaling Pathway antibodies	Growth Hormone Receptor Signaling Pathway Diagram
Immune System Pathway antibodies	Immune System Pathway Diagram
Jak-STAT Signaling Pathway antibodies	Jak-STAT Signaling Pathway Diagram
Jak-STAT Signaling Pathway antibodies	Jak-STAT Signaling Pathway Diagram
Metabolism Of Proteins Pathway antibodies	Metabolism Of Proteins Pathway Diagram
Neuroactive Ligand-receptor Interaction Pathway antibodies	Neuroactive Ligand-receptor Interaction Pathway Diagram
Neuroactive Ligand-receptor Interaction Pathway antibodies	Neuroactive Ligand-receptor Interaction Pathway Diagram
Nuclear Signaling By ERBB4 Pathway antibodies	Nuclear Signaling By ERBB4 Pathway Diagram
PI3K-Akt Signaling Pathway antibodies	PI3K-Akt Signaling Pathway Diagram

Diseases associated with bGH active protein

Disease Name	Pubmed Publications
Nervous System Diseases Antibodies	>70 publications with bGH and Nervous System Diseases
Pituitary Neoplasms Antibodies	>42 publications with bGH and Pituitary Neoplasms
Growth Disorders Antibodies	>27 publications with bGH and Growth Disorders
Breast Neoplasms Antibodies	>11 publications with bGH and Breast Neoplasms
Obesity Antibodies	>6 publications with bGH and Obesity
Liver Diseases Antibodies	>6 publications with bGH and Liver Diseases
Cardiovascular Diseases Antibodies	>6 publications with bGH and Cardiovascular Diseases
Insulin Resistance Antibodies	>6 publications with bGH and Insulin Resistance
Weight Gain Antibodies	>6 publications with bGH and Weight Gain
Isolated Growth Hormone Deficiency, Type II Antibodies	>3 publications with bGH and Isolated Growth Hormone Deficiency, Type II

Organs/Tissues associated with bGH active protein

Organ/Tissue Name	Pubmed Publications
Pituitary Gland Antibodies	>51 publications with bGH and Pituitary Gland
Brain Antibodies	>48 publications with bGH and Brain