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Semaglutide Active Protein

For Research Use Only. Not for use in diagnostic procedures. Catalog #: MBS407502

Glucagon-Like Peptide-1 (GLP-1) Analog Shown to Stimulate Insulin and Suppress Glucagon Secretion in a Glucose-Dependent Manner. Bolar Exemption applies. This is a FDA-regulated product. It is the responsibility of the customer to ensure that they are… More details

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Product Documentation
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Sample Manual Insert View PDF
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Testing Data View PDF
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Certificate of Analysis (COA) View PDF
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QC Report View PDF
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Material Safety Data Sheet View PDF
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Technical Datasheet View PDF
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Protocol View PDF

Product Overview

Product Name
Semaglutide, Active Protein
Full Product Name
Semaglutide
Product Synonym Names
H-His-Aib-Glu-Gly-Thr-Phe-Thr-Ser-Asp-Val-Ser-Ser-Tyr-Leu-Glu-Gly-Gln-Ala-Ala-Lys[(AEEA)2--Glu-N-(17-carboxy-1-oxoheptadecyl)]-Glu-Phe-Ile-Ala-Trp-Leu-Val-Arg-Gly-Arg-Gly-OH
Form/Format
Acetate Salt
Purity/Purification
HPLC Profile included (purity 97.6%)
Preparation and Storage
Store at -20°C (dry and frozen). The undissolved peptide is stable below -20C in the dark for more then one year. The solution stability has not been tested, therefore, prompt use is recommended.
Molecular Weight
4113.67
Active Protein Note
Protein activity can be an ambiguous term. Please refer to the data sheet or inquire with Technical Support to determine the definition of activity for this product.
Molecular Formula
C187H291N45O59
Net Peptide Content
80.0%
Appearance
White Powder
ES-MS
Found:
1372.0376 (3+)
1029.2742(4+)

Expected:
1372.2005 (3+)
1029.4023(4+)
Amino Acid Analysis
ASP 1.03 (1)
Thr 1.93 (2)
Ser 2.80 (3)
Glu 4.80 (5)
Gly 4.04 (4)
Ala 2.87 (3)
Val 2.16 (2)
IIe 0.96 (1)
Leu 1.98 (2)
Tyr 1.06 (1)
Phe 1.89 (2)
His 1.00 (1)
Lys 1.03 (1)
Arg 2.15 (2)
Trp: Not determined
Soluble
1mg in 50 ul of phosphate buffered saline
1 mg in 100 ul of 3% acetic acid (AcOH)
1 mg in 150 ul of DMSO; and does not remain in solution upon further dilution with sterile H2O
Insoluble
Sterile H2O
Application Notes for Semaglutide active protein
When dissolving peptides, first solbilize the peptide in appropriate solvent systems, then dilute with suitable buffers.

Product References and Citations for Semaglutide active protein

S.P. Marso, et al., N. Engl. J. Med., 375, 1834 (2016).
J. Lau, et al., J. Med. Chem., 58, 7370 (2015).
C.F. Gotfredsen, et al., Diabetes, 63, 2486: (2014).

Other Notes

Small volumes of Semaglutide active protein vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.

Searchable Terms for Semaglutide purchase

MBS407502 is an active protein targeting Semaglutide.
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