Thioredoxin Binding Protein 2 (TBP2) ELISA Kit for Rat

Name: Rat TBP2 ELISA Kit; Thioredoxin Binding Protein 2; MyBioSource
Brand: MyBioSource
SKU: MBS041174
Price: 675 USD
Availability: InStock
Rating: 5 (10 reviews)

For Research Use Only. Not for use in diagnostic procedures. Catalog #: MBS041174

Background: This Quantitative Sandwich ELISA kit is for lab reagent/research use only, not for drug, household, therapeutic or test applications! This kit is intended to be used to determine the level of TBP2 (hereafter termed "analyte") in undiluted original… More details

$675 / 48-Strip-Wells +1 FREE 8GB USB

Product Documentation

Sample Manual Insert View PDF

Testing Data View PDF

Certificate of Analysis (COA) View PDF

QC Report View PDF

Material Safety Data Sheet View PDF

Technical Datasheet View PDF

Protocol View PDF

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Product Overview

Online Datasheet in PDF

Product Name

Thioredoxin Binding Protein 2 (TBP2), ELISA Kit

Full Product Name

Rat Thioredoxin Binding Protein 2 ELISA Kit

Product Gene Name

TBP2 elisa kit

Species Reactivity

Rat

Assay Type

Quantitative Sandwich

Detection Range

0.625ng/ml-20ng/ml

Sensitivity

0.1ng/ml

Preparation and Storage

Store all reagents at 2-8 degree C

Inter-assay Precision

Inter-assay CV (%) is less than 15%. [CV(%) = SD/mean ×100]. All CV% should be compared by concentration, not compared by OD values.

Intra-assay Precision

Intra-assay CV (%) is less than 15%.

Molecular Weight

43,661 Da

OMIM

606599

3D Structure

ModBase 3D Structure for Q9H3M7

Other Notes

Small volumes of TBP2 elisa kit vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.

Searchable Terms for TBP2 purchase

MBS041174 is a ready-to-use microwell, strip plate ELISA (enzyme-linked immunosorbent assay) Kit for analyzing the presence of the Thioredoxin Binding Protein 2 (TBP2) ELISA Kit target analytes in biological samples. The concentration gradients of the kit standards or positive controls render a theoretical kit detection range in biological research samples containing TBP2. The ELISA analytical biochemical technique of the MBS041174 kit is based on TBP2 antibody-TBP2 antigen interactions (immunosorbency) and an HRP colorimetric detection system to detect TBP2 antigen targets in samples. The ELISA Kit is designed to detect native, not recombinant, TBP2. Appropriate sample types may include undiluted body fluids and/or tissue homogenates, secretions. Quality control assays assessing reproducibility identified the intra-assay CV (%) and inter-assay CV(%).

Additional Details

NCBI/Uniprot data below describe general gene information for TBP2. It may not necessarily be applicable to this product.

NCBI GI #

171184421

NCBI GeneID

10628

NCBI Accession #

NP_006463.3

UniProt Primary Accession #

Q9H3M7

UniProt Secondary Accession #

Q16226; Q6PML0; Q9BXG9; B4E3D3

UniProt Related Accession #

Q9H3M7

GenBank Nucleotide #

NM_006472.4

NCBI Official Full Name

thioredoxin-interacting protein

NCBI Official Synonym Full Names

thioredoxin interacting protein

NCBI Official Symbol

TXNIP

NCBI Official Synonym Symbols

THIF; VDUP1; HHCPA78; EST01027

UniProt Protein Name

Thioredoxin-interacting protein

UniProt Synonym Protein Names

Thioredoxin-binding protein 2; Vitamin D3 up-regulated protein 1

Protein Family

TATA-binding protein

UniProt Gene Name

TXNIP

UniProt Synonym Gene Names

VDUP1

UniProt Entry Name

TXNIP_HUMAN

NCBI Protein Information

thioredoxin-interacting protein; thioredoxin binding protein 2; thioredoxin-binding protein 2; vitamin D3 up-regulated protein 1; upregulated by 1,25-dihydroxyvitamin D-3

UniProt Comments for TBP2

TXNIP: May act as an oxidative stress mediator by inhibiting thioredoxin activity or by limiting its bioavailability. Interacts with COPS5 and restores COPS5-induced suppression of CDKN1B stability, blocking the COPS5-mediated translocation of CDKN1B from the nucleus to the cytoplasm. Functions as a transcriptional repressor, possibly by acting as a bridge molecule between transcription factors and corepressor complexes, and over- expression will induce G0/G1 cell cycle arrest. Required for the maturation of natural killer cells. Acts as a suppressor of tumor cell growth. Belongs to the arrestin family.

Protein type: Motility/polarity/chemotaxis; Apoptosis; Tumor suppressor; Mitochondrial

Chromosomal Location of Human Ortholog: 1q21.1

Cellular Component: cytoplasm; mitochondrial intermembrane space; nucleus; cytosol

Molecular Function: enzyme inhibitor activity; protein binding; ubiquitin protein ligase binding

Biological Process: response to drug; transcription, DNA-dependent; positive regulation of apoptosis; platelet-derived growth factor receptor signaling pathway; negative regulation of cell division; negative regulation of transcription from RNA polymerase II promoter; cell cycle; response to estradiol stimulus; regulation of cell proliferation; keratinocyte differentiation; response to hydrogen peroxide; response to mechanical stimulus; protein import into nucleus; negative regulation of catalytic activity; response to glucose stimulus; innate immune response; response to calcium ion; response to progesterone stimulus

Research Articles on TBP2

1. The results for the first time demonstrate FAK-regulated TXNIP expression which is important for apoptotic, survival and oxidative stress signaling pathways in cancer cells.

Precautions

All of MyBioSource's Products are for scientific laboratory research purposes and are not for diagnostic, therapeutics, prophylactic or in vivo use. Through your purchase, you expressly represent and warrant to MyBioSource that you will properly test and use any Products purchased from MyBioSource in accordance with industry standards. MyBioSource and its authorized distributors reserve the right to refuse to process any order where we reasonably believe that the intended use will fall outside of our acceptable guidelines.

Disclaimer

While every efforts were made to ensure the accuracy of the information provided in this datasheet, MyBioSource will not be liable for any omissions or errors contained herein. MyBioSource reserves the right to make changes to this datasheet at any time without prior notice.

It is the responsibility of the customer to report product performance issues to MyBioSource within 30 days of receipt of the product. Please visit our Terms & Conditions page for more information.

Product Note

Select online data sheet information is drawn from bioinformatics databases, occasionally resulting in ambiguous or non-relevant product information. It is the responsibility of the customer to review, verify, and evaluate the information to make sure it matches their requirements before purchasing the kit. Our ELISA Kit assays are dynamic research tools and sometimes they may be updated and improved. If the format of this assay is important to you then please request the current manual or contact our technical support team with a presales inquiry before placing an order. We will confirm the current details of the assay. We cannot guarantee the sample manual posted online is the most current manual, it is intended to serve as an example only. Please refer to the instructions For Use provided with the assay kit for precise details.

Product PubMed Publications

Products associated with TBP2 elisa kit

Reference Product	PubMed Publications
NLRP3 elisa kit	>22 publications with TBP2 and NLRP3
INS elisa kit	>15 publications with TBP2 and INS
TXN elisa kit	>12 publications with TBP2 and TXN
MLXIPL elisa kit	>5 publications with TBP2 and MLXIPL
KISS1 elisa kit	>2 publications with TBP2 and KISS1
BCL6 elisa kit	>1 publications with TBP2 and BCL6
HDAC10 elisa kit	>1 publications with TBP2 and HDAC10
IL2RB elisa kit	>1 publications with TBP2 and IL2RB

Pathways associated with TBP2 elisa kit

Products by Pathway	Pathway Diagram
Immune System Pathway antibodies	Immune System Pathway Diagram
Inflammasomes Pathway antibodies	Inflammasomes Pathway Diagram
Innate Immune System Pathway antibodies	Innate Immune System Pathway Diagram
Nucleotide-binding Domain, Leucine Rich Repeat Containing Receptor (NLR) Signaling Pathways antibodies	Nucleotide-binding Domain, Leucine Rich Repeat Containing Receptor (NLR) Signaling Pathways Diagram
The NLRP3 Inflammasome Pathway antibodies	The NLRP3 Inflammasome Pathway Diagram

Diseases associated with TBP2 elisa kit

Disease Name	Pubmed Publications
Neoplasms Antibodies	>90 publications with TBP2 and Neoplasms
Inflammation Antibodies	>63 publications with TBP2 and Inflammation
Cardiovascular Diseases Antibodies	>48 publications with TBP2 and Cardiovascular Diseases
Hyperglycemia Antibodies	>43 publications with TBP2 and Hyperglycemia
Disease Models, Animal Antibodies	>39 publications with TBP2 and Disease Models, Animal
Liver Diseases Antibodies	>20 publications with TBP2 and Liver Diseases
Heart Diseases Antibodies	>19 publications with TBP2 and Heart Diseases
Necrosis Antibodies	>18 publications with TBP2 and Necrosis
Kidney Diseases Antibodies	>16 publications with TBP2 and Kidney Diseases
Adenocarcinoma Antibodies	>16 publications with TBP2 and Adenocarcinoma

Organs/Tissues associated with TBP2 elisa kit

Organ/Tissue Name	Pubmed Publications
Blood Antibodies	>75 publications with TBP2 and Blood
Liver Antibodies	>45 publications with TBP2 and Liver
Vascular Antibodies	>41 publications with TBP2 and Vascular
Pancreas Antibodies	>35 publications with TBP2 and Pancreas
Muscle Antibodies	>33 publications with TBP2 and Muscle
Heart Antibodies	>33 publications with TBP2 and Heart
Kidney Antibodies	>29 publications with TBP2 and Kidney
Brain Antibodies	>19 publications with TBP2 and Brain
Eye Antibodies	>14 publications with TBP2 and Eye
Nerve Antibodies	>12 publications with TBP2 and Nerve