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IP10 Antibody – Mouse Monoclonal

For Research Use Only. Not for use in diagnostic procedures. Catalog #: MBS415383

MBS415383 is an antibody targeting IP10. Also known as Anti-IP10(CXCL10) Antibody. Host: Mouse. More details

$540 / 0.1 mL +1 FREE 8GB USB
Product Documentation
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Sample Manual Insert View PDF
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Testing Data View PDF
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Certificate of Analysis (COA) View PDF
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QC Report View PDF
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Material Safety Data Sheet View PDF
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Technical Datasheet View PDF
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Protocol View PDF

Product Overview

Online Datasheet in PDF
Product Name
IP10, Monoclonal Antibody
Full Product Name
Anti-IP10(CXCL10) Antibody
Product Gene Name
anti-IP10 antibody
Clonality
Monoclonal
Isotype
IgG1
Host
Mouse
Form/Format
Liquid
Purity/Purification
Affinity purified
Concentration
100ug/100ul (lot specific)
Specificity
Anti-CXCL10 recognizes recombinant protein CXCL10.
Preparation and Storage
This product is stable for several weeks at 4 degree C as an undiluted liquid. Dilute only prior to immediate use. For extended storage, aliquot contents and freeze at -20 degree C or below. Avoid cycles of freezing and thawing. Expiration date is one (1) year from date of receipt.
Molecular Weight
10,881 Da
OMIM
147310
Raised In
Purified mouse monoclonal antibody generated using E.coli expressed recombinant protein CXCL10 as immunogen.
Storage Buffer
citrate-tris-HCl buffer pH7.0 with 0.02% Proclin 300.
Immunogen
Recombinant protein corresponding to full length CXCL10
Applications Tested/Suitable for anti-IP10 antibody
ELISA (EIA), Western Blot (WB-Re), Immunohistochemistry (IHC)
Application Notes for anti-IP10 antibody
WB: 1:1000 analysis of recombinant protein CXCL10 with Anti-CXCL10
IHC: 1:10 to human liver tissue

Testing Data of anti-IP10 antibody

Mouse Anti-IP10 Monoclonal Antibody – Cat# MBS415383

Testing Data of anti-IP10 antibody

Mouse Anti-IP10 Monoclonal Antibody, Testing Data – Cat# MBS415383

Product References and Citations for anti-IP10 antibody

None

Other Notes

Small volumes of anti-IP10 antibody vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.

Additional Details

NCBI/Uniprot data below describe general gene information for IP10. It may not necessarily be applicable to this product.

NCBI GI #
149999381
NCBI GeneID
3627
NCBI Accession #
NP_001556.2
UniProt Secondary Accession #
Q96QJ5
UniProt Related Accession #
P02778
GenBank Nucleotide #
NM_001565.2
NCBI Official Full Name
Homo sapiens chemokine (C-X-C motif) ligand 10 (CXCL10), mRNA
NCBI Official Synonym Full Names
chemokine (C-X-C motif) ligand 10
NCBI Official Symbol
CXCL10
NCBI Official Synonym Symbols
C7; IFI10; INP10; IP-10; crg-2; mob-1; SCYB10; gIP-10
UniProt Protein Name
C-X-C motif chemokine 10
UniProt Synonym Protein Names
10 kDa interferon gamma-induced protein; Gamma-IP10; IP-10
Protein Family
C-X-C motif chemokine
UniProt Gene Name
CXCL10
UniProt Entry Name
CXL10_HUMAN
NCBI Protein Information
C-X-C motif chemokine 10; 10 kDa interferon gamma-induced protein; gamma IP10; gamma-IP10; interferon-inducible cytokine IP-10; protein 10 from interferon (gamma)-induced cell line; small inducible cytokine subfamily B (Cys-X-Cys), member 10; small-inducible cytokine B10

NCBI Summary for IP10

This antimicrobial gene encodes a chemokine of the CXC subfamily and ligand for the receptor CXCR3. Binding of this protein to CXCR3 results in pleiotropic effects, including stimulation of monocytes, natural killer and T-cell migration, and modulation of adhesion molecule expression. [provided by RefSeq, Sep 2014]
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UniProt Comments for IP10

CXCL10: Chemotactic for monocytes and T-lymphocytes. Binds to CXCR3. Belongs to the intercrine alpha (chemokine CxC) family.

Protein type: Chemokine; Secreted, signal peptide; Secreted; Motility/polarity/chemotaxis

Chromosomal Location of Human Ortholog: 4q21

Cellular Component: extracellular space; extracellular region; external side of plasma membrane

Molecular Function: heparin binding; protein binding; CXCR3 chemokine receptor binding; chemokine activity; cAMP-dependent protein kinase regulator activity; receptor binding

Biological Process: muscle development; blood circulation; protein secretion; positive regulation of leukocyte chemotaxis; positive regulation of cAMP metabolic process; chemotaxis; signal transduction; regulation of cell proliferation; G-protein coupled receptor protein signaling pathway; negative regulation of angiogenesis; cell surface receptor linked signal transduction; response to vitamin D; cell-cell signaling; positive regulation of cell proliferation; response to gamma radiation; positive regulation of transcription from RNA polymerase II promoter; immune response; response to cold; positive regulation of release of sequestered calcium ion into cytosol; regulation of protein kinase activity; negative regulation of myoblast differentiation; inflammatory response; defense response to virus
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Research Articles on IP10

1. Bile CXCL10 levels were significantly correlated with CD25 expression of CD8+ T cell subsets, especially in response to anti-donor stimulation

Precautions

All of MyBioSource's Products are for scientific laboratory research purposes and are not for diagnostic, therapeutics, prophylactic or in vivo use. Through your purchase, you expressly represent and warrant to MyBioSource that you will properly test and use any Products purchased from MyBioSource in accordance with industry standards. MyBioSource and its authorized distributors reserve the right to refuse to process any order where we reasonably believe that the intended use will fall outside of our acceptable guidelines.

Disclaimer

While every efforts were made to ensure the accuracy of the information provided in this datasheet, MyBioSource will not be liable for any omissions or errors contained herein. MyBioSource reserves the right to make changes to this datasheet at any time without prior notice.

It is the responsibility of the customer to report product performance issues to MyBioSource within 30 days of receipt of the product. Please visit our Terms & Conditions page for more information.

Product Note

Select online data sheet information is drawn from bioinformatics databases, occasionally resulting in ambiguous or non-relevant product information. It is the responsibility of the customer to review, verify, and evaluate the information to make sure it matches their requirements before purchasing the kit. Our ELISA Kit assays are dynamic research tools and sometimes they may be updated and improved. If the format of this assay is important to you then please request the current manual or contact our technical support team with a presales inquiry before placing an order. We will confirm the current details of the assay. We cannot guarantee the sample manual posted online is the most current manual, it is intended to serve as an example only. Please refer to the instructions For Use provided with the assay kit for precise details.

Product PubMed Publications

Products associated with anti-IP10 antibody

 Reference Product  PubMed Publications
 CXCL9 antibody  >913 publications with IP10 and CXCL9
 CXCR3 antibody  >830 publications with IP10 and CXCR3
 CCL5 antibody  >645 publications with IP10 and CCL5
 CXCL11 antibody  >464 publications with IP10 and CXCL11
 CCR5 antibody  >174 publications with IP10 and CCR5
 CCL20 antibody  >108 publications with IP10 and CCL20
 CCL11 antibody  >101 publications with IP10 and CCL11
 CXCR2 antibody  >51 publications with IP10 and CXCR2
 CCR1 antibody  >47 publications with IP10 and CCR1
 CCR3 antibody  >47 publications with IP10 and CCR3

Pathways associated with anti-IP10 antibody

 Products by Pathway  Pathway Diagram
 CXCR3-mediated Signaling Events Pathway antibodies  CXCR3-mediated Signaling Events Pathway Diagram
 Chemokine Receptors Bind Chemokines Pathway antibodies  Chemokine Receptors Bind Chemokines Pathway Diagram
 Chemokine Signaling Pathway antibodies  Chemokine Signaling Pathway Diagram
 Chemokine Signaling Pathway antibodies  Chemokine Signaling Pathway Diagram
 Class A/1 (Rhodopsin-like Receptors) Pathway antibodies  Class A/1 (Rhodopsin-like Receptors) Pathway Diagram
 Cytokine-cytokine Receptor Interaction Pathway antibodies  Cytokine-cytokine Receptor Interaction Pathway Diagram
 Cytokine-cytokine Receptor Interaction Pathway antibodies  Cytokine-cytokine Receptor Interaction Pathway Diagram
 Cytosolic DNA-sensing Pathway antibodies  Cytosolic DNA-sensing Pathway Diagram
 Cytosolic DNA-sensing Pathway antibodies  Cytosolic DNA-sensing Pathway Diagram
 Defective ACTH Causes Obesity And Pro-opiomelanocortinin Deficiency (POMCD) Pathway antibodies  Defective ACTH Causes Obesity And Pro-opiomelanocortinin Deficiency (POMCD) Pathway Diagram

Diseases associated with anti-IP10 antibody

 Disease Name  Pubmed Publications
 Inflammation Antibodies  >1165 publications with IP10 and Inflammation
 Necrosis Antibodies  >670 publications with IP10 and Necrosis
 Disease Models, Animal Antibodies  >339 publications with IP10 and Disease Models, Animal
 Lung Diseases Antibodies  >332 publications with IP10 and Lung Diseases
 Liver Diseases Antibodies  >232 publications with IP10 and Liver Diseases
 Brain Diseases Antibodies  >204 publications with IP10 and Brain Diseases
 Cardiovascular Diseases Antibodies  >169 publications with IP10 and Cardiovascular Diseases
 Fibrosis Antibodies  >128 publications with IP10 and Fibrosis
 Neoplasms, Experimental Antibodies  >113 publications with IP10 and Neoplasms, Experimental
 Kidney Diseases Antibodies  >87 publications with IP10 and Kidney Diseases

Organs/Tissues associated with anti-IP10 antibody

 Organ/Tissue Name  Pubmed Publications
 Blood Antibodies  >2027 publications with IP10 and Blood
 Lung Antibodies  >450 publications with IP10 and Lung
 Liver Antibodies  >270 publications with IP10 and Liver
 Kidney Antibodies  >179 publications with IP10 and Kidney
 Lymph Node Antibodies  >159 publications with IP10 and Lymph Node
 Muscle Antibodies  >119 publications with IP10 and Muscle
 Intestine Antibodies  >90 publications with IP10 and Intestine
 Nerve Antibodies  >60 publications with IP10 and Nerve
 Uterus Antibodies  >35 publications with IP10 and Uterus
 Placenta Antibodies  >28 publications with IP10 and Placenta
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