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ZFYVE16 Antibody – Rabbit Polyclonal

For Research Use Only. Not for use in diagnostic procedures. Catalog #: MBS415444

This gene encodes an endosomal protein that belongs to the FYVE zinc finger family of proteins. The encoded protein is thought to regulate membrane trafficking in the endosome. This protein functions as a scaffold protein in the transforming growth… More details

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Testing Data View PDF
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Product Overview

Product Name
ZFYVE16, Polyclonal Antibody
Full Product Name
Anti-ZFYVE16 Antibody
Product Gene Name
Clonality
Polyclonal
Host
Rabbit
Species Reactivity
Human. Predicted: Mouse, Rat.
Form/Format
Liquid
Purity/Purification
Affinity purified
Concentration
100ug/100ul (lot specific)
Preparation and Storage
This product is stable for several weeks at 4 degree C as an undiluted liquid. Dilute only prior to immediate use. For extended storage, aliquot contents and freeze at -20 degree C or below. Avoid cycles of freezing and thawing. Expiration date is one (1) year from date of receipt.
Molecular Weight
88,377 Da
OMIM
608880
Storage Buffer
PBS, pH 7.4 with 0.02% Sodium Azide
Immunogen
Rabbit polyclonal ZFYVE16 (1) antibody was raised against a recombinate human ZFYVE16 protein 369-623aa (BC030808).
Applications Tested/Suitable for anti-ZFYVE16 antibody
ELISA (EIA), Western Blot (WB), Immunohistochemistry (IHC)
Application Notes for anti-ZFYVE16 antibody
ELISA titer: 1:20,000-1:80,000
Western blot analysis: 1:500-1:1,000
Immunohistochemistry: 1:100-1:500
Optimal dilutions/concentrations should be determined by the end user

Testing Data of anti-ZFYVE16 antibody

Rabbit Anti-ZFYVE16 Polyclonal Antibody – Cat# MBS415444

Product References and Citations for anti-ZFYVE16 antibody

(1) Toy,W., Lim,S.K., Loh,M.C. and Lim,Y.P. EGF-induced tyrosine phosphorylation of Endofin is dependent on PI3K activity and proper localization to endosomes. Cell. Signal. 22 (3), 437-446 (2010).

Other Notes

Small volumes of anti-ZFYVE16 antibody vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.

Searchable Terms for ZFYVE16 purchase

MBS415444 is an antibody targeting ZFYVE16. Reactive in Human. Predicted: Mouse, Rat.. Host: Rabbit.

Additional Details

NCBI/Uniprot data below describe general gene information for ZFYVE16. It may not necessarily be applicable to this product.

NCBI GI #
NCBI GeneID
NCBI Accession #
UniProt Secondary Accession #
UniProt Related Accession #
NCBI Official Full Name
ZFYVE16 protein
NCBI Official Synonym Full Names
zinc finger, FYVE domain containing 16
NCBI Official Symbol
ZFYVE16
NCBI Official Synonym Symbols
PPP1R69
UniProt Protein Name
Zinc finger FYVE domain-containing protein 16
UniProt Synonym Protein Names
Endofin; Endosome-associated FYVE domain protein
UniProt Gene Name
ZFYVE16
UniProt Entry Name
ZFY16_HUMAN
NCBI Protein Information
zinc finger FYVE domain-containing protein 16; endosome-associated FYVE-domain protein; protein phosphatase 1, regulatory subunit 69

UniProt Comments for ZFYVE16

endofin: May be involved in regulating membrane trafficking in the endosomal pathway. Overexpression induces endosome aggregation. Required to target TOM1 to endosomes. 2 isoforms of the human protein are produced by alternative splicing.

Protein type: Lipid-binding

Chromosomal Location of Human Ortholog: 5q14

Cellular Component: intracellular membrane-bound organelle; early endosome membrane; cytoplasm; early endosome

Molecular Function: protein binding; phosphatidylinositol-3,4,5-triphosphate binding; metal ion binding; protein transporter activity; phosphatidylinositol binding

Biological Process: BMP signaling pathway; protein targeting to lysosome; vesicle organization and biogenesis; regulation of endocytosis; endosome transport; signal transduction
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Precautions

All of MyBioSource's Products are for scientific laboratory research purposes and are not for diagnostic, therapeutics, prophylactic or in vivo use. Through your purchase, you expressly represent and warrant to MyBioSource that you will properly test and use any Products purchased from MyBioSource in accordance with industry standards. MyBioSource and its authorized distributors reserve the right to refuse to process any order where we reasonably believe that the intended use will fall outside of our acceptable guidelines.

Disclaimer

While every efforts were made to ensure the accuracy of the information provided in this datasheet, MyBioSource will not be liable for any omissions or errors contained herein. MyBioSource reserves the right to make changes to this datasheet at any time without prior notice.

It is the responsibility of the customer to report product performance issues to MyBioSource within 30 days of receipt of the product. Please visit our Terms & Conditions page for more information.

Product Note

Select online data sheet information is drawn from bioinformatics databases, occasionally resulting in ambiguous or non-relevant product information. It is the responsibility of the customer to review, verify, and evaluate the information to make sure it matches their requirements before purchasing the kit. Our ELISA Kit assays are dynamic research tools and sometimes they may be updated and improved. If the format of this assay is important to you then please request the current manual or contact our technical support team with a presales inquiry before placing an order. We will confirm the current details of the assay. We cannot guarantee the sample manual posted online is the most current manual, it is intended to serve as an example only. Please refer to the instructions For Use provided with the assay kit for precise details.

Product PubMed Publications

Diseases associated with anti-ZFYVE16 antibody

 Disease Name  Pubmed Publications
 Fibrosis Antibodies  >3 publications with ZFYVE16 and Fibrosis
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