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PPARdelta Antibody – Rabbit Polyclonal

For Research Use Only. Not for use in diagnostic procedures. Catalog #: MBS415568

MBS415568 is an antibody targeting PPARdelta. Also known as PPARdelta Antibody. Reactive in Human. Host: Rabbit. PPARdelta is a Rabbit polyclonal to PPARdelta More details

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Product Documentation
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Sample Manual Insert View PDF
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Testing Data View PDF
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Certificate of Analysis (COA) View PDF
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QC Report View PDF
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Material Safety Data Sheet View PDF
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Technical Datasheet View PDF
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Protocol View PDF

Product Overview

Product Name
PPARdelta, Polyclonal Antibody
Full Product Name
PPARdelta Antibody
Product Gene Name
anti-PPARdelta antibody
Product Synonym Names
PPARdelta
Clonality
Polyclonal
Isotype
IgG
Host
Rabbit
Species Reactivity
Human
Form/Format
Liquid
Purity/Purification
Affinity purified
Concentration
1ug/ul (lot specific)
Specificity
This Polyclonal antibody is directed against human PPARdelta protein. The product was purified from seurm by protein A chromatography. Expect reactivity with human PPARdelta. Cross-reactivity with PPARdelta from other sources has not been determined.
Preparation and Storage
This product is stable for several weeks at 4 degree C as an undiluted liquid. Dilute only prior to immediate use. For extended storage, aliquot contents and freeze at -20 degree C or below. Avoid cycles of freezing and thawing. Expiration date is one (1) year from date of receipt.
Molecular Weight
49,715 Da
Chromosome Location
Chromosome: 17; NC_000083.6 (28232754..28301469). Location: 17 A3.3; 17 14.64 cM
3D Structure
ModBase 3D Structure for P35396
Immunogen
Synthetic peptide derived from Human PPARdelta.
Storage Buffer
PBS, pH 7.4 with 0.02% sodium azide.
Applications Tested/Suitable for anti-PPARdelta antibody
Western Blot (WB)

Western Blot (WB) of anti-PPARdelta antibody

Rabbit Anti-PPARdelta Polyclonal Antibody – Cat# MBS415568

Other Notes

Small volumes of anti-PPARdelta antibody vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.

Additional Details

NCBI/Uniprot data below describe general gene information for PPARdelta. It may not necessarily be applicable to this product.

NCBI GI #
33859590
NCBI GeneID
19015
NCBI Accession #
NP_035275.1
UniProt Primary Accession #
P35396
UniProt Secondary Accession #
P37239
UniProt Related Accession #
P35396
GenBank Nucleotide #
NM_011145.3
NCBI Official Full Name
peroxisome proliferator-activated receptor delta
NCBI Official Synonym Full Names
peroxisome proliferator activator receptor delta
NCBI Official Symbol
Ppard
NCBI Official Synonym Symbols
NUC1; NUC-1; Nr1c2; Pparb; PPAR[b]; Pparb/d; PPAR-beta; PPARdelta; PPAR-delta
UniProt Protein Name
Peroxisome proliferator-activated receptor delta
UniProt Synonym Protein Names
Nuclear hormone receptor 1; NUC1; Nuclear receptor subfamily 1 group C member 2; Peroxisome proliferator-activated receptor beta; PPAR-beta
UniProt Gene Name
Ppard
UniProt Synonym Gene Names
Nr1c2; Pparb; PPAR-delta; NUC1; PPAR-beta
UniProt Entry Name
PPARD_MOUSE
NCBI Protein Information
peroxisome proliferator-activated receptor delta; PPARdelta/beta; nuclear hormone receptor 1; nuclear receptor subfamily 1 group C member 2; Peroxisome proliferator-activated receptor beta

UniProt Comments for PPARdelta

Function: Ligand-activated transcription factor. Receptor that binds peroxisome proliferators such as hypolipidemic drugs and fatty acids. Has a preference for poly-unsaturated fatty acids, such as gamma-linoleic acid and eicosapentanoic acid. Once activated by a ligand, the receptor binds to promoter elements of target genes. Regulates the peroxisomal beta-oxidation pathway of fatty acids. Functions as transcription activator for the acyl-CoA oxidase gene. Decreases expression of NPC1L1 once activated by a ligand

By similarity.

Subunit structure: Heterodimer with the retinoid X receptor.

Subcellular location: Nucleus.

Tissue specificity: Heart, adrenal and intestine.

Sequence similarities: Belongs to the nuclear hormone receptor family. NR1 subfamily.Contains 1 nuclear receptor DNA-binding domain.

Sequence caution: The sequence AAA03332.1 differs from that shown. Reason: Erroneous initiation.
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Research Articles on PPARdelta

1. differences in DNA binding of other transcription factors can directly influence the transcriptional activity of PPARbeta/delta

Precautions

All of MyBioSource's Products are for scientific laboratory research purposes and are not for diagnostic, therapeutics, prophylactic or in vivo use. Through your purchase, you expressly represent and warrant to MyBioSource that you will properly test and use any Products purchased from MyBioSource in accordance with industry standards. MyBioSource and its authorized distributors reserve the right to refuse to process any order where we reasonably believe that the intended use will fall outside of our acceptable guidelines.

Disclaimer

While every efforts were made to ensure the accuracy of the information provided in this datasheet, MyBioSource will not be liable for any omissions or errors contained herein. MyBioSource reserves the right to make changes to this datasheet at any time without prior notice.

It is the responsibility of the customer to report product performance issues to MyBioSource within 30 days of receipt of the product. Please visit our Terms & Conditions page for more information.

Product Note

Select online data sheet information is drawn from bioinformatics databases, occasionally resulting in ambiguous or non-relevant product information. It is the responsibility of the customer to review, verify, and evaluate the information to make sure it matches their requirements before purchasing the kit. Our ELISA Kit assays are dynamic research tools and sometimes they may be updated and improved. If the format of this assay is important to you then please request the current manual or contact our technical support team with a presales inquiry before placing an order. We will confirm the current details of the assay. We cannot guarantee the sample manual posted online is the most current manual, it is intended to serve as an example only. Please refer to the instructions For Use provided with the assay kit for precise details.

Product PubMed Publications

Pathways associated with anti-PPARdelta antibody

 Products by Pathway  Pathway Diagram
 Acute Myeloid Leukemia Pathway antibodies  Acute Myeloid Leukemia Pathway Diagram
 Acute Myeloid Leukemia Pathway antibodies  Acute Myeloid Leukemia Pathway Diagram
 Adipogenesis Pathway antibodies  Adipogenesis Pathway Diagram
 Gene Expression Pathway antibodies  Gene Expression Pathway Diagram
 Generic Transcription Pathway antibodies  Generic Transcription Pathway Diagram
 Nuclear Receptor Transcription Pathway antibodies  Nuclear Receptor Transcription Pathway Diagram
 Nuclear Receptors Pathway antibodies  Nuclear Receptors Pathway Diagram
 Nuclear Receptors In Lipid Metabolism And Toxicity Pathway antibodies  Nuclear Receptors In Lipid Metabolism And Toxicity Pathway Diagram
 PPAR (Peroxisome Proliferator-activated Receptor) Signaling Pathway antibodies  PPAR (Peroxisome Proliferator-activated Receptor) Signaling Pathway Diagram
 PPAR Signaling Pathway antibodies  PPAR Signaling Pathway Diagram

Diseases associated with anti-PPARdelta antibody

 Disease Name  Pubmed Publications
 Obesity Antibodies  >20 publications with PPARdelta and Obesity
 Insulin Resistance Antibodies  >13 publications with PPARdelta and Insulin Resistance
 Fatty Liver Antibodies  >7 publications with PPARdelta and Fatty Liver
 Heart Diseases Antibodies  >6 publications with PPARdelta and Heart Diseases
 Inflammation Antibodies  >5 publications with PPARdelta and Inflammation
 Dyslipidemias Antibodies  >4 publications with PPARdelta and Dyslipidemias
 Hypertension Antibodies  >4 publications with PPARdelta and Hypertension
 Hyperlipidemias Antibodies  >4 publications with PPARdelta and Hyperlipidemias
 Necrosis Antibodies  >3 publications with PPARdelta and Necrosis
 Drug Toxicity Antibodies  >3 publications with PPARdelta and Drug Toxicity

Organs/Tissues associated with anti-PPARdelta antibody

 Organ/Tissue Name  Pubmed Publications
 Liver Antibodies  >14 publications with PPARdelta and Liver
 Heart Antibodies  >7 publications with PPARdelta and Heart
 Uterus Antibodies  >4 publications with PPARdelta and Uterus
 Brain Antibodies  >4 publications with PPARdelta and Brain
 Embryonic Tissue Antibodies  >3 publications with PPARdelta and Embryonic Tissue
 Intestine Antibodies  >3 publications with PPARdelta and Intestine
 Skin Antibodies  >2 publications with PPARdelta and Skin
 Thymus Antibodies  >1 publications with PPARdelta and Thymus
 Mammary Gland Antibodies  >1 publications with PPARdelta and Mammary Gland
 Spleen Antibodies  >1 publications with PPARdelta and Spleen
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