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ENTPD4 Antibody – Rabbit Polyclonal

For Research Use Only. Not for use in diagnostic procedures. Catalog #: MBS415592

This gene encodes a member of the apyrase protein family. Apyrases are enzymes that catalyze the hydrolysis of nucleotide diphosphates and triphosphates in a calcium or magnesium-dependent manner. The encoded protein is an endo-apyrase and may play a role in… More details

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Product Overview

Product Name
ENTPD4, Polyclonal Antibody
Full Product Name
Anti-ENTPD4 Antibody
Product Gene Name
anti-ENTPD4 antibody
Product Synonym Names
Anti-ENTPD1 Antibody
Clonality
Polyclonal
Host
Rabbit
Species Reactivity
Human. Predicted: Mouse, Rat.
Form/Format
Liquid
Purity/Purification
Affinity purified
Concentration
100ug/100ul (lot specific)
Preparation and Storage
This product is stable for several weeks at 4 degree C as an undiluted liquid. Dilute only prior to immediate use. For extended storage, aliquot contents and freeze at -20 degree C or below. Avoid cycles of freezing and thawing. Expiration date is one (1) year from date of receipt.
Molecular Weight
59,325 Da
OMIM
601752
Storage Buffer
PBS, pH 7.4 with 0.02% Sodium Azide
Immunogen
Rabbit polyclonal ENTPD4 (1) antibody was raised against a recombinate human ENTPD4 protein 374-551 aa (BC034477).
Applications Tested/Suitable for anti-ENTPD4 antibody
ELISA (EIA), Western Blot (WB), Immunohistochemistry (IHC)
Application Notes for anti-ENTPD4 antibody
ELISA titer: 1:20,000-1:80,000
Western blot analysis: 1:500-1:1,000
Immunohistochemistry: 1:100-1:500
Optimal dilutions/concentrations should be determined by the end user.

Testing Data of anti-ENTPD4 antibody

Rabbit Anti-ENTPD4 Polyclonal Antibody – Cat# MBS415592

Product References and Citations for anti-ENTPD4 antibody

(1) Saito,A., Fujikura-Ouchi,Y., Ito,C. et al. An association study on polymorphisms in the PEA15, ENTPD4, and GAS2L1 genes and schizophrenia. Psychiatry Res 185 (1-2), 9-15 (2011).

Other Notes

Small volumes of anti-ENTPD4 antibody vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.

Searchable Terms for ENTPD4 purchase

MBS415592 is an antibody targeting ENTPD4. Reactive in Human. Predicted: Mouse, Rat.. Host: Rabbit.

Additional Details

NCBI/Uniprot data below describe general gene information for ENTPD4. It may not necessarily be applicable to this product.

NCBI GI #
256355134
NCBI GeneID
953
NCBI Accession #
NP_001157655.1
UniProt Secondary Accession #
Q5T561; Q5T562; Q86VV3; Q9UQQ9; Q9Y3Q9; A9Z1X8; B4DWB9; B4E1X1; B7Z599; G3XAF6
UniProt Related Accession #
P49961
GenBank Nucleotide #
NM_001164183.1
NCBI Official Full Name
ectonucleoside triphosphate diphosphohydrolase 1 isoform 6
NCBI Official Synonym Full Names
ectonucleoside triphosphate diphosphohydrolase 1
NCBI Official Symbol
ENTPD1
NCBI Official Synonym Symbols
CD39; SPG64; ATPDase; NTPDase-1
UniProt Protein Name
Ectonucleoside triphosphate diphosphohydrolase 1
UniProt Synonym Protein Names
Ecto-ATP diphosphohydrolase 1; Ecto-ATPDase 1; Ecto-ATPase 1; Ecto-apyrase; Lymphoid cell activation antigen; CD_antigen: CD39
Protein Family
Ectonucleoside triphosphate diphosphohydrolase
UniProt Gene Name
ENTPD1
UniProt Entry Name
ENTP1_HUMAN
NCBI Protein Information
ectonucleoside triphosphate diphosphohydrolase 1; CD39 antigen; NTPDase 1; ecto-ATP diphosphohydrolase 1; ecto-ATPDase 1; ecto-ATPase 1; ecto-apyrase; lymphoid cell activation antigen

NCBI Summary for ENTPD4

The protein encoded by this gene is a plasma membrane protein that hydrolyzes extracellular ATP and ADP to AMP. Inhibition of this protein's activity may confer anticancer benefits. Several transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Aug 2015]

UniProt Comments for ENTPD4

ENTPD1: In the nervous system, could hydrolyze ATP and other nucleotides to regulate purinergic neurotransmission. Could also be implicated in the prevention of platelet aggregation by hydrolyzing platelet-activating ADP to AMP. Hydrolyzes ATP and ADP equally well. Belongs to the GDA1/CD39 NTPase family. 5 isoforms of the human protein are produced by alternative splicing.

Protein type: Nucleotide Metabolism - pyrimidine; Membrane protein, integral; Hydrolase; Nucleotide Metabolism - purine; Membrane protein, multi-pass; EC 3.6.1.5; Extracellular matrix

Chromosomal Location of Human Ortholog: 10q24

Cellular Component: membrane; integral to plasma membrane; plasma membrane; basal lamina

Molecular Function: protein binding; nucleoside-diphosphatase activity; nucleoside-triphosphatase activity; ATP binding

Biological Process: platelet activation; G-protein coupled receptor protein signaling pathway; blood coagulation; purine ribonucleoside diphosphate catabolic process; cell adhesion

Disease: Spastic Paraplegia 64, Autosomal Recessive
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Research Articles on ENTPD4

1. Our data suggests that human bone marrow-derived mesenchymal stem cells can effectively suppress immune responses of the Th17 cells via the CD39-CD73-mediated adenosine-producing pathway

Precautions

All of MyBioSource's Products are for scientific laboratory research purposes and are not for diagnostic, therapeutics, prophylactic or in vivo use. Through your purchase, you expressly represent and warrant to MyBioSource that you will properly test and use any Products purchased from MyBioSource in accordance with industry standards. MyBioSource and its authorized distributors reserve the right to refuse to process any order where we reasonably believe that the intended use will fall outside of our acceptable guidelines.

Disclaimer

While every efforts were made to ensure the accuracy of the information provided in this datasheet, MyBioSource will not be liable for any omissions or errors contained herein. MyBioSource reserves the right to make changes to this datasheet at any time without prior notice.

It is the responsibility of the customer to report product performance issues to MyBioSource within 30 days of receipt of the product. Please visit our Terms & Conditions page for more information.

Product Note

Select online data sheet information is drawn from bioinformatics databases, occasionally resulting in ambiguous or non-relevant product information. It is the responsibility of the customer to review, verify, and evaluate the information to make sure it matches their requirements before purchasing the kit. Our ELISA Kit assays are dynamic research tools and sometimes they may be updated and improved. If the format of this assay is important to you then please request the current manual or contact our technical support team with a presales inquiry before placing an order. We will confirm the current details of the assay. We cannot guarantee the sample manual posted online is the most current manual, it is intended to serve as an example only. Please refer to the instructions For Use provided with the assay kit for precise details.

Product PubMed Publications

Products associated with anti-ENTPD4 antibody

 Reference Product  PubMed Publications
 NT5E antibody  >3 publications with ENTPD4 and NT5E
 ENTPD6 antibody  >1 publications with ENTPD4 and ENTPD6
 ENTPD5 antibody  >1 publications with ENTPD4 and ENTPD5

Pathways associated with anti-ENTPD4 antibody

 Products by Pathway  Pathway Diagram
 Epstein-Barr Virus Infection Pathway antibodies  Epstein-Barr Virus Infection Pathway Diagram
 Epstein-Barr Virus Infection Pathway antibodies  Epstein-Barr Virus Infection Pathway Diagram
 Purine Metabolism Pathway antibodies  Purine Metabolism Pathway Diagram
 Purine Metabolism Pathway antibodies  Purine Metabolism Pathway Diagram
 Pyrimidine Metabolism Pathway antibodies  Pyrimidine Metabolism Pathway Diagram
 Pyrimidine Metabolism Pathway antibodies  Pyrimidine Metabolism Pathway Diagram
 UTP And CTP Dephosphorylation II Pathway antibodies  UTP And CTP Dephosphorylation II Pathway Diagram
 UTP And CTP Dephosphorylation II Pathway antibodies  UTP And CTP Dephosphorylation II Pathway Diagram

Diseases associated with anti-ENTPD4 antibody

 Disease Name  Pubmed Publications
 Inflammation Antibodies  >13 publications with ENTPD4 and Inflammation
 Disease Models, Animal Antibodies  >8 publications with ENTPD4 and Disease Models, Animal
 Neoplasms, Experimental Antibodies  >5 publications with ENTPD4 and Neoplasms, Experimental
 Necrosis Antibodies  >5 publications with ENTPD4 and Necrosis
 Liver Neoplasms Antibodies  >3 publications with ENTPD4 and Liver Neoplasms
 Liver Diseases Antibodies  >3 publications with ENTPD4 and Liver Diseases
 Kidney Diseases Antibodies  >3 publications with ENTPD4 and Kidney Diseases
 Insulin Resistance Antibodies  >2 publications with ENTPD4 and Insulin Resistance
 Nervous System Diseases Antibodies  >2 publications with ENTPD4 and Nervous System Diseases
 Proteinuria Antibodies  >1 publications with ENTPD4 and Proteinuria

Organs/Tissues associated with anti-ENTPD4 antibody

 Organ/Tissue Name  Pubmed Publications
 Blood Antibodies  >22 publications with ENTPD4 and Blood
 Muscle Antibodies  >9 publications with ENTPD4 and Muscle
 Liver Antibodies  >8 publications with ENTPD4 and Liver
 Kidney Antibodies  >4 publications with ENTPD4 and Kidney
 Heart Antibodies  >3 publications with ENTPD4 and Heart
 Pancreas Antibodies  >3 publications with ENTPD4 and Pancreas
 Bone Marrow Antibodies  >3 publications with ENTPD4 and Bone Marrow
 Bone Antibodies  >3 publications with ENTPD4 and Bone
 Embryonic Tissue Antibodies  >2 publications with ENTPD4 and Embryonic Tissue
 Skin Antibodies  >2 publications with ENTPD4 and Skin
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