Rabbit Anti-YES1 Polyclonal Antibody – Cat# MBS415794

YES1 Antibody – Rabbit Polyclonal

Name: YES1 Antibody; Polyclonal; Rabbit; Human/Mouse/Rat-Reactive; MyBioSource
Brand: MyBioSource
SKU: MBS415794
Price: 335 USD
Availability: InStock
Rating: 5 (10 reviews)

For Research Use Only. Not for use in diagnostic procedures. Catalog #: MBS415794

This gene is the cellular homolog of the Yamaguchi sarcoma virus oncogene. The encoded protein has tyrosine kinase activity and belongs to the src family of proteins. This gene lies in close proximity to thymidylate synthase gene on chromosome 18, and a… More details

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Product Documentation

Sample Manual Insert View PDF

Testing Data View PDF

Certificate of Analysis (COA) View PDF

QC Report View PDF

Material Safety Data Sheet View PDF

Technical Datasheet View PDF

Protocol View PDF

Product Overview

Product Name

YES1, Polyclonal Antibody

Full Product Name

Anti-YES1 Antibody

Product Gene Name

anti-YES1 antibody

Clonality

Polyclonal

Host

Rabbit

Species Reactivity

Human. Predicted: Mouse, Rat

Form/Format

Liquid

Purity/Purification

Affinity purified

Concentration

100ug/100ul (lot specific)

Preparation and Storage

This product is stable for several weeks at 4 degree C as an undiluted liquid. Dilute only prior to immediate use. For extended storage, aliquot contents and freeze at -20 degree C or below. Avoid cycles of freezing and thawing. Expiration date is one (1) year from date of receipt.

Molecular Weight

60,801 Da

OMIM

164880

Storage Buffer

PBS, pH 7.4 with 0.02% Sodium Azide

Immunogen

Rabbit polyclonal YES1 (1) antibody was raised against a recombinated human YES1 protein 416-538aa (BC048960).

Applications Tested/Suitable for anti-YES1 antibody

ELISA (EIA), Western Blot (WB), Immunohistochemistry (IHC)

Application Notes for anti-YES1 antibody

ELISA titer: 1:20,000-1:80,000
Western blot analysis: 1:500-1:1,000
Immunohistochemistry: 1:100-1:500
Optimal dilutions/concentrations should be determined by the end user.

Product References and Citations for anti-YES1 antibody

(1) Hamamura,K., Tsuji,M., Hotta,H., et al. Functional activation of Src family kinase yes protein is essential for the enhanced malignant properties of human melanoma cells expressing ganglioside GD3. J. Biol. Chem. 286 (21), 18526-18537 (2011).

Other Notes

Small volumes of anti-YES1 antibody vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.

Searchable Terms for YES1 purchase

MBS415794 is an antibody targeting YES1. Reactive in Human. Predicted: Mouse, Rat. Host: Rabbit.

Additional Details

NCBI/Uniprot data below describe general gene information for YES1. It may not necessarily be applicable to this product.

NCBI GI #

29124495

NCBI GeneID

7525

NCBI Accession #

BC048960

UniProt Secondary Accession #

A6NLB3; D3DUH1

UniProt Related Accession #

P07947

NCBI Official Full Name

Homo sapiens v-yes-1 Yamaguchi sarcoma viral oncogene homolog 1, mRNA

NCBI Official Synonym Full Names

YES proto-oncogene 1, Src family tyrosine kinase

NCBI Official Symbol

YES1

NCBI Official Synonym Symbols

Yes; c-yes; HsT441; P61-YES

UniProt Protein Name

Tyrosine-protein kinase Yes

UniProt Synonym Protein Names

Proto-oncogene c-Yes; p61-Yes

Protein Family

Tyrosine-protein kinase

UniProt Gene Name

YES1

UniProt Entry Name

YES_HUMAN

NCBI Protein Information

tyrosine-protein kinase Yes; YES1 proto-oncogene, Src family tyrosine kinase; Yamaguchi sarcoma oncogene; cellular yes-1 protein; proto-oncogene c-Yes; proto-oncogene tyrosine-protein kinase YES; v-yes-1 Yamaguchi sarcoma viral oncogene homolog 1

UniProt Comments for YES1

Yes: a proto-oncogenic cytosolic tyrosine kinase of the Src family. Expressed at high levels in adult neurons, spermatozoa, platelets, and epithelial cells.

Protein type: Kinase, protein; Protein kinase, TK; Oncoprotein; EC 2.7.10.2; Protein kinase, tyrosine (non-receptor); TK group; Src family

Chromosomal Location of Human Ortholog: 18p11.31-p11.21

Cellular Component: Golgi apparatus; extrinsic to internal side of plasma membrane; focal adhesion; cytoplasm; plasma membrane; microtubule organizing center; actin filament; cytosol

Molecular Function: protein binding; enzyme binding; protein-tyrosine kinase activity; non-membrane spanning protein tyrosine kinase activity; ATP binding; receptor binding; epidermal growth factor receptor binding

Biological Process: axon guidance; T cell costimulation; ephrin receptor signaling pathway; protein modification process; innate immune response; glucose transport; regulation of vascular permeability; cell differentiation; blood coagulation; leukocyte migration; transmembrane receptor protein tyrosine kinase signaling pathway; regulation of cell proliferation

Research Articles on YES1

1. YES1 and YAP transcript levels were higher in liver metastases of patients with colon cancer after 5FU-based neoadjuvant chemotherapy.

Precautions

All of MyBioSource's Products are for scientific laboratory research purposes and are not for diagnostic, therapeutics, prophylactic or in vivo use. Through your purchase, you expressly represent and warrant to MyBioSource that you will properly test and use any Products purchased from MyBioSource in accordance with industry standards. MyBioSource and its authorized distributors reserve the right to refuse to process any order where we reasonably believe that the intended use will fall outside of our acceptable guidelines.

Disclaimer

While every efforts were made to ensure the accuracy of the information provided in this datasheet, MyBioSource will not be liable for any omissions or errors contained herein. MyBioSource reserves the right to make changes to this datasheet at any time without prior notice.

It is the responsibility of the customer to report product performance issues to MyBioSource within 30 days of receipt of the product. Please visit our Terms & Conditions page for more information.

Product Note

Select online data sheet information is drawn from bioinformatics databases, occasionally resulting in ambiguous or non-relevant product information. It is the responsibility of the customer to review, verify, and evaluate the information to make sure it matches their requirements before purchasing the kit. Our ELISA Kit assays are dynamic research tools and sometimes they may be updated and improved. If the format of this assay is important to you then please request the current manual or contact our technical support team with a presales inquiry before placing an order. We will confirm the current details of the assay. We cannot guarantee the sample manual posted online is the most current manual, it is intended to serve as an example only. Please refer to the instructions For Use provided with the assay kit for precise details.

Product PubMed Publications

Products associated with anti-YES1 antibody

Reference Product	PubMed Publications
FYN antibody	>63 publications with YES1 and FYN
OCLN antibody	>1 publications with YES1 and OCLN
JAK2 antibody	>1 publications with YES1 and JAK2

Pathways associated with anti-YES1 antibody

Products by Pathway	Pathway Diagram
Adaptive Immune System Pathway antibodies	Adaptive Immune System Pathway Diagram
Adherens Junction Pathway antibodies	Adherens Junction Pathway Diagram
Adherens Junction Pathway antibodies	Adherens Junction Pathway Diagram
Alpha-synuclein Signaling Pathway antibodies	Alpha-synuclein Signaling Pathway Diagram
Alpha6-Beta4 Integrin Signaling Pathway antibodies	Alpha6-Beta4 Integrin Signaling Pathway Diagram
Axon Guidance Pathway antibodies	Axon Guidance Pathway Diagram
CD28 Co-stimulation Pathway antibodies	CD28 Co-stimulation Pathway Diagram
CDC42 Signaling Events Pathway antibodies	CDC42 Signaling Events Pathway Diagram
CTLA4 Inhibitory Signaling Pathway antibodies	CTLA4 Inhibitory Signaling Pathway Diagram
CXCR4-mediated Signaling Events Pathway antibodies	CXCR4-mediated Signaling Events Pathway Diagram

Diseases associated with anti-YES1 antibody

Disease Name	Pubmed Publications
Carcinoma Antibodies	>20 publications with YES1 and Carcinoma
Adenocarcinoma Antibodies	>9 publications with YES1 and Adenocarcinoma
Carcinoma, Squamous Cell Antibodies	>7 publications with YES1 and Carcinoma, Squamous Cell
Neoplasm Metastasis Antibodies	>6 publications with YES1 and Neoplasm Metastasis
Nervous System Diseases Antibodies	>5 publications with YES1 and Nervous System Diseases
Liver Neoplasms Antibodies	>5 publications with YES1 and Liver Neoplasms
Neoplasms, Experimental Antibodies	>5 publications with YES1 and Neoplasms, Experimental
Lung Diseases Antibodies	>4 publications with YES1 and Lung Diseases
Liver Diseases Antibodies	>4 publications with YES1 and Liver Diseases
Inflammation Antibodies	>4 publications with YES1 and Inflammation

Organs/Tissues associated with anti-YES1 antibody

Organ/Tissue Name	Pubmed Publications
Brain Antibodies	>14 publications with YES1 and Brain
Liver Antibodies	>11 publications with YES1 and Liver
Lung Antibodies	>8 publications with YES1 and Lung
Vascular Antibodies	>8 publications with YES1 and Vascular
Kidney Antibodies	>7 publications with YES1 and Kidney
Pancreas Antibodies	>6 publications with YES1 and Pancreas
Skin Antibodies	>5 publications with YES1 and Skin
Muscle Antibodies	>4 publications with YES1 and Muscle
Testis Antibodies	>4 publications with YES1 and Testis
Esophagus Antibodies	>3 publications with YES1 and Esophagus