Rabbit Anti-AIBZIP Polyclonal Antibody – Cat# MBS416001

AIBZIP Antibody – Rabbit Polyclonal

Name: AIBZIP Antibody; Polyclonal; Rabbit; Human/Mouse/Rat-Reactive; MyBioSource
Brand: MyBioSource
SKU: MBS416001
Price: 335 USD
Availability: InStock
Rating: 5 (10 reviews)

For Research Use Only. Not for use in diagnostic procedures. Catalog #: MBS416001

MBS416001 is an antibody targeting AIBZIP. Also known as Anti-AIBZIP - CREB3L4 Antibody. Reactive in Human. Predicted: Mouse, Rat.. Host: Rabbit. More details

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Product Documentation

Sample Manual Insert View PDF

Testing Data View PDF

Certificate of Analysis (COA) View PDF

QC Report View PDF

Material Safety Data Sheet View PDF

Technical Datasheet View PDF

Protocol View PDF

Product Overview

Product Name

AIBZIP, Polyclonal Antibody

Full Product Name

Anti-AIBZIP - CREB3L4 Antibody

Product Gene Name

anti-AIBZIP antibody

Product Synonym Names

Anti-AIBZIP Antibody

Clonality

Polyclonal

Host

Rabbit

Species Reactivity

Human. Predicted: Mouse, Rat.

Form/Format

Liquid

Purity/Purification

Affinity purified

Concentration

100ug/100ul (lot specific)

Preparation and Storage

This product is stable for several weeks at 4 degree C as an undiluted liquid. Dilute only prior to immediate use. For extended storage, aliquot contents and freeze at -20 degree C or below. Avoid cycles of freezing and thawing. Expiration date is one (1) year from date of receipt.

Molecular Weight

41,275 Da

OMIM

607138

Storage Buffer

PBS, pH 7.4 with 0.02% Sodium Azide

Immunogen

Rabbit polyclonal AIBZIP(1) antibody was raised against a peptide corresponding to the C terminal amino acids of Human AIBZIP. The peptide sequence: PSGRIRSVLHADEM.

Applications Tested/Suitable for anti-AIBZIP antibody

Peptide ELISA (EIA), Western Blot (WB), Immunohistochemistry (IHC)

Application Notes for anti-AIBZIP antibody

Peptide ELISA titer: 1:20,000-1:80,000
Western blot analysis: 1:1,000-1:2,000
Immunohistochemistry: 1:100-1:500
Optimal dilutions/concentrations should be determined by the end user.

Product References and Citations for anti-AIBZIP antibody

Qi,H., Fillion,C., Labrie,Y.,,et,al. AIbZIP,a novel bZIP gene located on chromosome 1q21.3 that is highly expressed in prostate tumors and of which the expression is up-regulated by androgens in LNCaP human prostate cancer cells. Cancer Research.2002;62:721-733.

Other Notes

Small volumes of anti-AIBZIP antibody vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.

Additional Details

NCBI/Uniprot data below describe general gene information for AIBZIP. It may not necessarily be applicable to this product.

NCBI GI #

18623504

NCBI GeneID

148327

NCBI Accession #

AAL76113.1

UniProt Secondary Accession #

Q5T4L0; Q86YW6; D3DV62

UniProt Related Accession #

Q8TEY5

NCBI Official Full Name

androgen-induced basic leucine zipper

NCBI Official Synonym Full Names

cAMP responsive element binding protein 3-like 4

NCBI Official Symbol

CREB3L4

NCBI Official Synonym Symbols

JAL; hJAL; ATCE1; CREB3; CREB4; AIBZIP

UniProt Protein Name

Cyclic AMP-responsive element-binding protein 3-like protein 4

UniProt Synonym Protein Names

Androgen-induced basic leucine zipper protein; AIbZIP

UniProt Gene Name

CREB3L4

UniProt Entry Name

CR3L4_HUMAN

NCBI Protein Information

cyclic AMP-responsive element-binding protein 3-like protein 4; CREB-4; androgen-induced basic leucine zipper protein; attaching to CRE-like 1; cAMP responsive element binding protein 1; cAMP-responsive element-binding protein 3-like protein 4; cAMP-responsive element-binding protein 4; cyclic AMP-responsive element-binding protein 4; tisp40; transcript induced in spermiogenesis protein 40

NCBI Summary for AIBZIP

This gene encodes a CREB (cAMP responsive element binding) protein with a transmembrane domain which localizes it to the ER membrane. The encoded protein is a transcriptional activator which contains a dimerization domain, and this protein may function in a number of processing pathways including protein processing. Multiple transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Dec 2011]

UniProt Comments for AIBZIP

CREB3L4: Transcriptional activator that may play a role in the unfolded protein response. Binds to the UPR element (UPRE) but not to CRE element. Preferentially binds DNA with to the consensus sequence 5'-T[GT]ACGT[GA][GT]-3' and has transcriptional activation activity from UPRE. Binds to NF-kappa-B site and has transcriptional activation activity from NF-kappa-B-containing regulatory elements. Belongs to the bZIP family. ATF subfamily.

Protein type: Transcription factor; Endoplasmic reticulum; Membrane protein, integral

Chromosomal Location of Human Ortholog: 1q21.3

Cellular Component: Golgi membrane; Golgi apparatus; endoplasmic reticulum membrane; endoplasmic reticulum; integral to membrane; nucleus

Biological Process: transcription, DNA-dependent; unfolded protein response; spermatogenesis; positive regulation of transcription from RNA polymerase II promoter

Research Articles on AIBZIP

1. In LNCaP cell lines that conditionally express the processed form of AIbZIP, downstream targets of AIbZIP include genes for protein processing, transcriptional regulation, small molecule transport, signal transduction, metabolism & cell homeostasis.

Precautions

All of MyBioSource's Products are for scientific laboratory research purposes and are not for diagnostic, therapeutics, prophylactic or in vivo use. Through your purchase, you expressly represent and warrant to MyBioSource that you will properly test and use any Products purchased from MyBioSource in accordance with industry standards. MyBioSource and its authorized distributors reserve the right to refuse to process any order where we reasonably believe that the intended use will fall outside of our acceptable guidelines.

Disclaimer

While every efforts were made to ensure the accuracy of the information provided in this datasheet, MyBioSource will not be liable for any omissions or errors contained herein. MyBioSource reserves the right to make changes to this datasheet at any time without prior notice.

It is the responsibility of the customer to report product performance issues to MyBioSource within 30 days of receipt of the product. Please visit our Terms & Conditions page for more information.

Product Note

Select online data sheet information is drawn from bioinformatics databases, occasionally resulting in ambiguous or non-relevant product information. It is the responsibility of the customer to review, verify, and evaluate the information to make sure it matches their requirements before purchasing the kit. Our ELISA Kit assays are dynamic research tools and sometimes they may be updated and improved. If the format of this assay is important to you then please request the current manual or contact our technical support team with a presales inquiry before placing an order. We will confirm the current details of the assay. We cannot guarantee the sample manual posted online is the most current manual, it is intended to serve as an example only. Please refer to the instructions For Use provided with the assay kit for precise details.

Product PubMed Publications

Pathways associated with anti-AIBZIP antibody

Products by Pathway	Pathway Diagram
AMPK Signaling Pathway antibodies	AMPK Signaling Pathway Diagram
AMPK Signaling Pathway antibodies	AMPK Signaling Pathway Diagram
Adrenergic Signaling In Cardiomyocytes Pathway antibodies	Adrenergic Signaling In Cardiomyocytes Pathway Diagram
Adrenergic Signaling In Cardiomyocytes Pathway antibodies	Adrenergic Signaling In Cardiomyocytes Pathway Diagram
Alcoholism Pathway antibodies	Alcoholism Pathway Diagram
Alcoholism Pathway antibodies	Alcoholism Pathway Diagram
Amphetamine Addiction Pathway antibodies	Amphetamine Addiction Pathway Diagram
Amphetamine Addiction Pathway antibodies	Amphetamine Addiction Pathway Diagram
Cholinergic Synapse Pathway antibodies	Cholinergic Synapse Pathway Diagram
Cocaine Addiction Pathway antibodies	Cocaine Addiction Pathway Diagram

Diseases associated with anti-AIBZIP antibody

Disease Name	Pubmed Publications
Prostatic Neoplasms Antibodies	>6 publications with AIBZIP and Prostatic Neoplasms
Adenocarcinoma Antibodies	>5 publications with AIBZIP and Adenocarcinoma
Hyperplasia Antibodies	>2 publications with AIBZIP and Hyperplasia
Liver Diseases Antibodies	>1 publications with AIBZIP and Liver Diseases
Breast Neoplasms Antibodies	>1 publications with AIBZIP and Breast Neoplasms

Organs/Tissues associated with anti-AIBZIP antibody

Organ/Tissue Name	Pubmed Publications
Prostate Antibodies	>9 publications with AIBZIP and Prostate
Testis Antibodies	>5 publications with AIBZIP and Testis
Liver Antibodies	>4 publications with AIBZIP and Liver
Lung Antibodies	>2 publications with AIBZIP and Lung
Brain Antibodies	>2 publications with AIBZIP and Brain
Nerve Antibodies	>2 publications with AIBZIP and Nerve
Pancreas Antibodies	>2 publications with AIBZIP and Pancreas
Heart Antibodies	>1 publications with AIBZIP and Heart
Intestine Antibodies	>1 publications with AIBZIP and Intestine
Placenta Antibodies	>1 publications with AIBZIP and Placenta