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EphA7 Antibody – Rabbit Polyclonal

For Research Use Only. Not for use in diagnostic procedures. Catalog #: MBS416079

This gene belongs to the ephrin receptor subfamily of the protein-tyrosine kinase family. EPH and EPH-related receptors have been implicated in mediating developmental events, particularly in the nervous system. Receptors in the EPH subfamily typically have a… More details

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Testing Data View PDF
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Technical Datasheet View PDF
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Product Overview

Product Name
EphA7, Polyclonal Antibody
Full Product Name
Anti-EphA7 Antibody
Product Gene Name
anti-EphA7 antibody
Product Synonym Names
Anti-EPHA7 Antibody
Clonality
Polyclonal
Isotype
IgG
Host
Rabbit
Species Reactivity
Human. Not yet tested in other species
Form/Format
Liquid
Purity/Purification
Affinity purified
Concentration
100ug/100ul (lot specific)
Preparation and Storage
This product is stable for several weeks at 4 degree C as an undiluted liquid. Dilute only prior to immediate use. For extended storage, aliquot contents and freeze at -20 degree C or below. Avoid cycles of freezing and thawing. Expiration date is one (1) year from date of receipt.
Molecular Weight
50,521 Da
OMIM
602190
Storage Buffer
PBS, pH 7.4 with 0.02% Sodium Azide
Immunogen
Rabbit polyclonal EPHA7 antibody was raised against a peptide from near the C terminal residues of human EPHA7 protein.
Applications Tested/Suitable for anti-EphA7 antibody
ELISA (EIA), Immunohistochemistry (IHC)
Application Notes for anti-EphA7 antibody
Peptide ELISA titer: 1:1,000-1:10,000
Immunohistochemistry: 1:50-200
Optimal dilutions/concentrations should be determined by the end user

Immunohistochemistry (IHC) of anti-EphA7 antibody

Rabbit Anti-EphA7 Polyclonal Antibody – Cat# MBS416079

Product References and Citations for anti-EphA7 antibody

(1) Wang,L.F., Fokas,E., Juricko,J., et al. Increased expression of EphA7 correlates with adverse outcome in primary and recurrent glioblastoma multiforme patients.BMC Cancer 8, 79 (2008)

Other Notes

Small volumes of anti-EphA7 antibody vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.

Searchable Terms for EphA7 purchase

MBS416079 is an antibody targeting EphA7. Reactive in Human. Not yet tested in other species. Host: Rabbit.

Additional Details

NCBI/Uniprot data below describe general gene information for EphA7. It may not necessarily be applicable to this product.

NCBI GI #
4758282
NCBI GeneID
2045
NCBI Accession #
NP_004431.1
UniProt Secondary Accession #
Q59G40; Q5VTU0; Q8N368; Q9H124; A0AUX7; B2R8W1; B7ZLJ9; B7ZLK0
UniProt Related Accession #
Q15375
GenBank Nucleotide #
NM_004440.3
NCBI Official Full Name
ephrin type-A receptor 7 isoform 1
NCBI Official Synonym Full Names
EPH receptor A7
NCBI Official Symbol
EPHA7
NCBI Official Synonym Symbols
EHK3; EK11; EHK-3; HEK11
UniProt Protein Name
Ephrin type-A receptor 7
UniProt Synonym Protein Names
EPH homology kinase 3; EHK-3; EPH-like kinase 11; EK11; hEK11
Protein Family
Ephrin type-A receptor
UniProt Gene Name
EPHA7
UniProt Entry Name
EPHA7_HUMAN
NCBI Protein Information
ephrin type-A receptor 7; EPH homology kinase 3; EPH-like kinase 11; Eph homology kinase-3; receptor protein-tyrosine kinase HEK11; tyrosine-protein kinase receptor EHK-3

UniProt Comments for EphA7

EphA7: a widely-expressed receptor tyrosine kinase of the Eph family. Receptor for members of the ephrin-A family. Binds to ephrin-A1, -A2, -A3, -A4 and -A5. Contains 1 sterile alpha motif (SAM) and two fibronectin type III domains.

Protein type: Kinase, protein; Membrane protein, integral; Protein kinase, tyrosine (receptor); Protein kinase, TK; EC 2.7.10.1; TK group; Eph family

Chromosomal Location of Human Ortholog: 6q16.1

Cellular Component: postsynaptic membrane; cell soma; integral to plasma membrane; dendrite; plasma membrane; neuromuscular junction

Molecular Function: protein binding; ephrin receptor binding; protein-tyrosine kinase activity; chemorepellent activity; GPI-linked ephrin receptor activity; axon guidance receptor activity; ATP binding

Biological Process: axon guidance; peptidyl-tyrosine phosphorylation; branching morphogenesis of a nerve; regulation of protein amino acid autophosphorylation; negative chemotaxis; regulation of caspase activity; regulation of cell-cell adhesion; positive regulation of neuron apoptosis; ephrin receptor signaling pathway; brain development; phosphorylation; regulation of peptidyl-tyrosine phosphorylation; retinal ganglion cell axon guidance
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Research Articles on EphA7

1. MTDH and EphA7 are markers for metastasis and poor prognosis of gallbladder adenocarcinoma.

Precautions

All of MyBioSource's Products are for scientific laboratory research purposes and are not for diagnostic, therapeutics, prophylactic or in vivo use. Through your purchase, you expressly represent and warrant to MyBioSource that you will properly test and use any Products purchased from MyBioSource in accordance with industry standards. MyBioSource and its authorized distributors reserve the right to refuse to process any order where we reasonably believe that the intended use will fall outside of our acceptable guidelines.

Disclaimer

While every efforts were made to ensure the accuracy of the information provided in this datasheet, MyBioSource will not be liable for any omissions or errors contained herein. MyBioSource reserves the right to make changes to this datasheet at any time without prior notice.

It is the responsibility of the customer to report product performance issues to MyBioSource within 30 days of receipt of the product. Please visit our Terms & Conditions page for more information.

Product Note

Select online data sheet information is drawn from bioinformatics databases, occasionally resulting in ambiguous or non-relevant product information. It is the responsibility of the customer to review, verify, and evaluate the information to make sure it matches their requirements before purchasing the kit. Our ELISA Kit assays are dynamic research tools and sometimes they may be updated and improved. If the format of this assay is important to you then please request the current manual or contact our technical support team with a presales inquiry before placing an order. We will confirm the current details of the assay. We cannot guarantee the sample manual posted online is the most current manual, it is intended to serve as an example only. Please refer to the instructions For Use provided with the assay kit for precise details.

Product PubMed Publications

Products associated with anti-EphA7 antibody

 Reference Product  PubMed Publications
 EPHA4 antibody  >38 publications with EphA7 and EPHA4
 EPHA3 antibody  >23 publications with EphA7 and EPHA3
 EPHA5 antibody  >19 publications with EphA7 and EPHA5
 EPHA6 antibody  >10 publications with EphA7 and EPHA6
 SRC antibody  >3 publications with EphA7 and SRC
 EFNA3 antibody  >1 publications with EphA7 and EFNA3
 EFNA5 antibody  >1 publications with EphA7 and EFNA5

Pathways associated with anti-EphA7 antibody

 Products by Pathway  Pathway Diagram
 Axon Guidance Pathway antibodies  Axon Guidance Pathway Diagram
 Axon Guidance Pathway antibodies  Axon Guidance Pathway Diagram
 Axon Guidance Pathway antibodies  Axon Guidance Pathway Diagram
 Developmental Biology Pathway antibodies  Developmental Biology Pathway Diagram
 EPH-Ephrin Signaling Pathway antibodies  EPH-Ephrin Signaling Pathway Diagram
 EPH-ephrin Mediated Repulsion Of Cells Pathway antibodies  EPH-ephrin Mediated Repulsion Of Cells Pathway Diagram
 EPHA Forward Signaling Pathway antibodies  EPHA Forward Signaling Pathway Diagram
 EPHA-mediated Growth Cone Collapse Pathway antibodies  EPHA-mediated Growth Cone Collapse Pathway Diagram
 EphrinA-EPHA Pathway antibodies  EphrinA-EPHA Pathway Diagram

Diseases associated with anti-EphA7 antibody

 Disease Name  Pubmed Publications
 Congenital Abnormalities Antibodies  >7 publications with EphA7 and Congenital Abnormalities
 Adenocarcinoma Antibodies  >6 publications with EphA7 and Adenocarcinoma
 Nervous System Diseases Antibodies  >6 publications with EphA7 and Nervous System Diseases
 Inflammation Antibodies  >3 publications with EphA7 and Inflammation
 Nervous System Malformations Antibodies  >3 publications with EphA7 and Nervous System Malformations
 Necrosis Antibodies  >3 publications with EphA7 and Necrosis
 Small Cell Lung Carcinoma Antibodies  >3 publications with EphA7 and Small Cell Lung Carcinoma
 Breast Neoplasms Antibodies  >2 publications with EphA7 and Breast Neoplasms
 Prostatic Neoplasms Antibodies  >2 publications with EphA7 and Prostatic Neoplasms
 Pain Antibodies  >2 publications with EphA7 and Pain

Organs/Tissues associated with anti-EphA7 antibody

 Organ/Tissue Name  Pubmed Publications
 Brain Antibodies  >61 publications with EphA7 and Brain
 Embryonic Tissue Antibodies  >20 publications with EphA7 and Embryonic Tissue
 Eye Antibodies  >16 publications with EphA7 and Eye
 Vascular Antibodies  >9 publications with EphA7 and Vascular
 Bone Antibodies  >8 publications with EphA7 and Bone
 Lung Antibodies  >7 publications with EphA7 and Lung
 Ear Antibodies  >6 publications with EphA7 and Ear
 Kidney Antibodies  >4 publications with EphA7 and Kidney
 Muscle Antibodies  >4 publications with EphA7 and Muscle
 Prostate Antibodies  >3 publications with EphA7 and Prostate
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