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PGM3 Antibody – Rabbit Polyclonal

For Research Use Only. Not for use in diagnostic procedures. Catalog #: MBS416101

MBS416101 is an antibody targeting PGM3. Reactive in Human. Host: Rabbit. Rabbit polyclonal PGM3 More details

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Product Documentation
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Sample Manual Insert View PDF
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Testing Data View PDF
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Certificate of Analysis (COA) View PDF
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QC Report View PDF
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Material Safety Data Sheet View PDF
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Technical Datasheet View PDF
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Protocol View PDF

Product Overview

Product Name
PGM3, Polyclonal Antibody
Full Product Name
Anti-PGM3 Antibody
Product Gene Name
anti-PGM3 antibody
Clonality
Polyclonal
Host
Rabbit
Species Reactivity
Human
Form/Format
Liquid
Purity/Purification
Affinity purified
Concentration
100ug/100ul (lot specific)
Preparation and Storage
This product is stable for several weeks at 4 degree C as an undiluted liquid. Dilute only prior to immediate use. For extended storage, aliquot contents and freeze at -20 degree C or below. Avoid cycles of freezing and thawing. Expiration date is one (1) year from date of receipt.
Molecular Weight
62,941 Da
OMIM
172100
Storage Buffer
PBS, pH 7.4 with 0.02% Sodium Azide
Immunogen
Raised against a recombinate human PGM3 protein 61-318aa (BC001258).
Applications Tested/Suitable for anti-PGM3 antibody
ELISA (EIA), Western Blot (WB), Immunohistochemistry (IHC)
Application Notes for anti-PGM3 antibody
ELISA titer: 1:20,000-1:80,000
Western blot analysis: 1:1,000-1:2,000
Immunohistochemistry: 1:100-1:500
Optimal dilutions/concentrations should be determined by the end user.

Western Blot (WB) of anti-PGM3 antibody

Rabbit Anti-PGM3 Polyclonal Antibody – Cat# MBS416101

Immunohistochemistry (IHC) #2 of anti-PGM3 antibody

Rabbit Anti-PGM3 Polyclonal Antibody, Immunohistochemistry (IHC) #2 – Cat# MBS416101

Product References and Citations for anti-PGM3 antibody

(1) Pang,H., Li,Z., Wang,B. and Ding,M. Polymorphic analysis of the human phosphoglucomutase-3 gene based on mismatched PCR-RFLP technique. Biochem. Genet. 48 (3-4), 208-214 (2010).

Other Notes

Small volumes of anti-PGM3 antibody vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.

Additional Details

NCBI/Uniprot data below describe general gene information for PGM3. It may not necessarily be applicable to this product.

NCBI GI #
12654830
NCBI GeneID
5238
NCBI Accession #
BC001258
UniProt Secondary Accession #
Q5JWR4; Q96J46; Q9H8G5; Q9NS94; Q9NTT6; Q9UFV5; B2RB65; B4DX94; D6RF12; E1P547; E9PF86
UniProt Related Accession #
O95394
NCBI Official Full Name
Homo sapiens phosphoglucomutase 3, mRNA
NCBI Official Synonym Full Names
phosphoglucomutase 3
NCBI Official Symbol
PGM3
NCBI Official Synonym Symbols
AGM1; PAGM; IMD23; PGM 3
UniProt Protein Name
Phosphoacetylglucosamine mutase
UniProt Synonym Protein Names
Acetylglucosamine phosphomutase
UniProt Gene Name
PGM3
UniProt Entry Name
AGM1_HUMAN
NCBI Protein Information
phosphoacetylglucosamine mutase; N-acetylglucosamine-phosphate mutase 1; acetylglucosamine phosphomutase

NCBI Summary for PGM3

This gene encodes a member of the phosphohexose mutase family. The encoded protein mediates both glycogen formation and utilization by catalyzing the interconversion of glucose-1-phosphate and glucose-6-phosphate. A non-synonymous single nucleotide polymorphism in this gene may play a role in resistance to diabetic nephropathy and neuropathy. Alternatively spliced transcript variants encoding multiple isoforms have been observed for this gene. [provided by RefSeq, Dec 2010]
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UniProt Comments for PGM3

PGM3: Interconverts GlcNAc-6-P and GlcNAc-1-P. Belongs to the phosphohexose mutase family.

Protein type: EC 5.4.2.3; Isomerase; Carbohydrate Metabolism - amino sugar and nucleotide sugar

Chromosomal Location of Human Ortholog: 6q14.1-q15

Cellular Component: cytosol

Molecular Function: phosphoglucomutase activity; magnesium ion binding; phosphoacetylglucosamine mutase activity

Biological Process: protein amino acid O-linked glycosylation; cellular protein metabolic process; dolichol-linked oligosaccharide biosynthetic process; protein amino acid N-linked glycosylation; UDP-N-acetylglucosamine biosynthetic process; protein amino acid N-linked glycosylation via asparagine; glucose 1-phosphate metabolic process; hemopoiesis; spermatogenesis; post-translational protein modification; glucosamine metabolic process

Disease: Immunodeficiency 23
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Research Articles on PGM3

1. define PGM3-CDG as a treatable immunodeficiency, document the power of whole-exome sequencing in gene discoveries for rare disorders, and illustrate the utility of genomic analyses in studying combined and variable phenotypes

Precautions

All of MyBioSource's Products are for scientific laboratory research purposes and are not for diagnostic, therapeutics, prophylactic or in vivo use. Through your purchase, you expressly represent and warrant to MyBioSource that you will properly test and use any Products purchased from MyBioSource in accordance with industry standards. MyBioSource and its authorized distributors reserve the right to refuse to process any order where we reasonably believe that the intended use will fall outside of our acceptable guidelines.

Disclaimer

While every efforts were made to ensure the accuracy of the information provided in this datasheet, MyBioSource will not be liable for any omissions or errors contained herein. MyBioSource reserves the right to make changes to this datasheet at any time without prior notice.

It is the responsibility of the customer to report product performance issues to MyBioSource within 30 days of receipt of the product. Please visit our Terms & Conditions page for more information.

Product Note

Select online data sheet information is drawn from bioinformatics databases, occasionally resulting in ambiguous or non-relevant product information. It is the responsibility of the customer to review, verify, and evaluate the information to make sure it matches their requirements before purchasing the kit. Our ELISA Kit assays are dynamic research tools and sometimes they may be updated and improved. If the format of this assay is important to you then please request the current manual or contact our technical support team with a presales inquiry before placing an order. We will confirm the current details of the assay. We cannot guarantee the sample manual posted online is the most current manual, it is intended to serve as an example only. Please refer to the instructions For Use provided with the assay kit for precise details.

Product PubMed Publications

Pathways associated with anti-PGM3 antibody

 Products by Pathway  Pathway Diagram
 Amino Sugar And Nucleotide Sugar Metabolism Pathway antibodies  Amino Sugar And Nucleotide Sugar Metabolism Pathway Diagram
 Amino Sugar And Nucleotide Sugar Metabolism Pathway antibodies  Amino Sugar And Nucleotide Sugar Metabolism Pathway Diagram
 Asparagine N-linked Glycosylation Pathway antibodies  Asparagine N-linked Glycosylation Pathway Diagram
 Biosynthesis Of The N-glycan Precursor (dolichol Lipid-linked Oligosaccharide, LLO) And Transfer To A Nascent Protein Pathway antibodies  Biosynthesis Of The N-glycan Precursor (dolichol Lipid-linked Oligosaccharide, LLO) And Transfer To A Nascent Protein Pathway Diagram
 Defective ALG1 Causes ALG1-CDG (CDG-1k) Pathway antibodies  Defective ALG1 Causes ALG1-CDG (CDG-1k) Pathway Diagram
 Defective ALG11 Causes ALG11-CDG (CDG-1p) Pathway antibodies  Defective ALG11 Causes ALG11-CDG (CDG-1p) Pathway Diagram
 Defective ALG12 Causes ALG12-CDG (CDG-1g) Pathway antibodies  Defective ALG12 Causes ALG12-CDG (CDG-1g) Pathway Diagram
 Defective ALG14 Causes Congenital Myasthenic Syndrome (ALG14-CMS) Pathway antibodies  Defective ALG14 Causes Congenital Myasthenic Syndrome (ALG14-CMS) Pathway Diagram
 Defective ALG2 Causes ALG2-CDG (CDG-1i) Pathway antibodies  Defective ALG2 Causes ALG2-CDG (CDG-1i) Pathway Diagram
 Defective ALG3 Causes ALG3-CDG (CDG-1d) Pathway antibodies  Defective ALG3 Causes ALG3-CDG (CDG-1d) Pathway Diagram

Diseases associated with anti-PGM3 antibody

 Disease Name  Pubmed Publications
 Nervous System Diseases Antibodies  >3 publications with PGM3 and Nervous System Diseases
 Mental Disorders Antibodies  >2 publications with PGM3 and Mental Disorders
 Memory Disorders Antibodies  >1 publications with PGM3 and Memory Disorders
 Fibrosis Antibodies  >1 publications with PGM3 and Fibrosis
 Abnormalities, Multiple Antibodies  >1 publications with PGM3 and Abnormalities, Multiple
 Fetal Death Antibodies  >1 publications with PGM3 and Fetal Death
 Brain Diseases Antibodies  >1 publications with PGM3 and Brain Diseases
 Cognition Disorders Antibodies  >1 publications with PGM3 and Cognition Disorders

Organs/Tissues associated with anti-PGM3 antibody

 Organ/Tissue Name  Pubmed Publications
 Blood Antibodies  >45 publications with PGM3 and Blood
 Placenta Antibodies  >11 publications with PGM3 and Placenta
 Embryonic Tissue Antibodies  >5 publications with PGM3 and Embryonic Tissue
 Muscle Antibodies  >4 publications with PGM3 and Muscle
 Kidney Antibodies  >3 publications with PGM3 and Kidney
 Skin Antibodies  >3 publications with PGM3 and Skin
 Bone Antibodies  >3 publications with PGM3 and Bone
 Brain Antibodies  >3 publications with PGM3 and Brain
 Bone Marrow Antibodies  >2 publications with PGM3 and Bone Marrow
 Liver Antibodies  >2 publications with PGM3 and Liver
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