Rabbit Anti-HS2ST1 Polyclonal Antibody – Cat# MBS416163

HS2ST1 Antibody – Rabbit Polyclonal

Name: HS2ST1 Antibody; Polyclonal; Rabbit; Human/Mouse/Rat-Reactive; MyBioSource
Brand: MyBioSource
SKU: MBS416163
Price: 335 USD
Availability: InStock
Rating: 5 (10 reviews)

For Research Use Only. Not for use in diagnostic procedures. Catalog #: MBS416163

Heparan sulfate biosynthetic enzymes are key components in generating a myriad of distinct heparan sulfate fine structures that carry out multiple biologic activities. This gene encodes a member of the heparan sulfate biosynthetic enzyme family that transfers… More details

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Product Documentation

Sample Manual Insert View PDF

Testing Data View PDF

Certificate of Analysis (COA) View PDF

QC Report View PDF

Material Safety Data Sheet View PDF

Technical Datasheet View PDF

Protocol View PDF

Product Overview

Product Name

HS2ST1, Polyclonal Antibody

Full Product Name

Anti-HS2ST1 Antibody

Product Gene Name

anti-HS2ST1 antibody

Clonality

Polyclonal

Host

Rabbit

Species Reactivity

Human. Predicted: Mouse, Rat. Not yet tested in other species.

Form/Format

Liquid

Purity/Purification

Affinity purified

Concentration

100ug/100ul (lot specific)

Preparation and Storage

This product is stable for several weeks at 4 degree C as an undiluted liquid. Dilute only prior to immediate use. For extended storage, aliquot contents and freeze at -20 degree C or below. Avoid cycles of freezing and thawing. Expiration date is one (1) year from date of receipt.

Molecular Weight

26,757 Da

OMIM

604844

Storage Buffer

PBS, pH 7.4 with 0.02% Sodium Azide

Applications Tested/Suitable for anti-HS2ST1 antibody

ELISA (EIA), Western Blot (WB), Immunohistochemistry (IHC)

Application Notes for anti-HS2ST1 antibody

ELISA titer: 1:20,000-1:80,000
Western blot analysis: 1:1,000-1:2,000
Immunohistochemistry: 1:100-1:500
Optimal dilutions/concentrations should be determined by the end user

Product References and Citations for anti-HS2ST1 antibody

(1) Casabonne,D., Reina,O., Benavente,Y., et al. Single nucleotide polymorphisms of matrix metalloproteinase 9 (MMP9) and tumor protein 73 (TP73) interact with Epstein-Barr virus in chronic lymphocytic leukemia: results from the European case-control study EpiLymph. Haematologica 96 (2), 323-327 (2011)

Other Notes

Small volumes of anti-HS2ST1 antibody vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.

Searchable Terms for HS2ST1 purchase

MBS416163 is an antibody targeting HS2ST1. Reactive in Human. Predicted: Mouse, Rat. Not yet tested in other species.. Host: Rabbit.

Additional Details

NCBI/Uniprot data below describe general gene information for HS2ST1. It may not necessarily be applicable to this product.

NCBI GI #

80477761

NCBI GeneID

9653

NCBI Accession #

AAI08736.1

UniProt Secondary Accession #

O75036; Q32NB5; Q8TAC5; Q9H441; Q9NUJ9; D3DT22

UniProt Related Accession #

Q7LGA3

NCBI Official Full Name

HS2ST1 protein

NCBI Official Synonym Full Names

heparan sulfate 2-O-sulfotransferase 1

NCBI Official Symbol

HS2ST1

NCBI Official Synonym Symbols

dJ604K5.2

UniProt Protein Name

Heparan sulfate 2-O-sulfotransferase 1

Protein Family

Heparan sulfate 2-O-sulfotransferase

UniProt Gene Name

HS2ST1

UniProt Entry Name

HS2ST_HUMAN

NCBI Protein Information

heparan sulfate 2-O-sulfotransferase 1; 2OST

UniProt Comments for HS2ST1

HS2ST1: Catalyzes the transfer of sulfate to the C2-position of selected hexuronic acid residues within the maturing heparan sulfate (HS). 2-O-sulfation within HS, particularly of iduronate residues, is essential for HS to participate in a variety of high- affinity ligand-binding interactions and signaling processes. Mediates 2-O-sulfation of both L-iduronyl and D-glucuronyl residues. Belongs to the sulfotransferase 3 family. 3 isoforms of the human protein are produced by alternative splicing.

Protein type: Motility/polarity/chemotaxis; Membrane protein, integral; EC 2.8.2.-; Glycan Metabolism - heparan sulfate biosynthesis; Transferase

Chromosomal Location of Human Ortholog: 1p22.3

Cellular Component: Golgi membrane; membrane; integral to membrane

Molecular Function: sulfotransferase activity

Biological Process: glycosaminoglycan biosynthetic process; glycosaminoglycan metabolic process; carbohydrate metabolic process; pathogenesis

Research Articles on HS2ST1

1. Observational study of gene-disease association and gene-environment interaction. (HuGE Navigator)

Precautions

All of MyBioSource's Products are for scientific laboratory research purposes and are not for diagnostic, therapeutics, prophylactic or in vivo use. Through your purchase, you expressly represent and warrant to MyBioSource that you will properly test and use any Products purchased from MyBioSource in accordance with industry standards. MyBioSource and its authorized distributors reserve the right to refuse to process any order where we reasonably believe that the intended use will fall outside of our acceptable guidelines.

Disclaimer

While every efforts were made to ensure the accuracy of the information provided in this datasheet, MyBioSource will not be liable for any omissions or errors contained herein. MyBioSource reserves the right to make changes to this datasheet at any time without prior notice.

It is the responsibility of the customer to report product performance issues to MyBioSource within 30 days of receipt of the product. Please visit our Terms & Conditions page for more information.

Product Note

Select online data sheet information is drawn from bioinformatics databases, occasionally resulting in ambiguous or non-relevant product information. It is the responsibility of the customer to review, verify, and evaluate the information to make sure it matches their requirements before purchasing the kit. Our ELISA Kit assays are dynamic research tools and sometimes they may be updated and improved. If the format of this assay is important to you then please request the current manual or contact our technical support team with a presales inquiry before placing an order. We will confirm the current details of the assay. We cannot guarantee the sample manual posted online is the most current manual, it is intended to serve as an example only. Please refer to the instructions For Use provided with the assay kit for precise details.

Product PubMed Publications

Products associated with anti-HS2ST1 antibody

Reference Product	PubMed Publications
HS3ST2 antibody	>1 publications with HS2ST1 and HS3ST2
GLCE antibody	>1 publications with HS2ST1 and GLCE
HS3ST6 antibody	>1 publications with HS2ST1 and HS3ST6

Pathways associated with anti-HS2ST1 antibody

Products by Pathway	Pathway Diagram
Defective B3GAT3 Causes JDSSDHD Pathway antibodies	Defective B3GAT3 Causes JDSSDHD Pathway Diagram
Defective B4GALT1 Causes B4GALT1-CDG (CDG-2d) Pathway antibodies	Defective B4GALT1 Causes B4GALT1-CDG (CDG-2d) Pathway Diagram
Defective B4GALT7 Causes EDS, Progeroid Type Pathway antibodies	Defective B4GALT7 Causes EDS, Progeroid Type Pathway Diagram
Defective CHST14 Causes EDS, Musculocontractural Type Pathway antibodies	Defective CHST14 Causes EDS, Musculocontractural Type Pathway Diagram
Defective CHST3 Causes SEDCJD Pathway antibodies	Defective CHST3 Causes SEDCJD Pathway Diagram
Defective CHST6 Causes MCDC1 Pathway antibodies	Defective CHST6 Causes MCDC1 Pathway Diagram
Defective CHSY1 Causes TPBS Pathway antibodies	Defective CHSY1 Causes TPBS Pathway Diagram
Defective EXT1 Causes Exostoses 1, TRPS2 And CHDS Pathway antibodies	Defective EXT1 Causes Exostoses 1, TRPS2 And CHDS Pathway Diagram
Defective EXT2 Causes Exostoses 2 Pathway antibodies	Defective EXT2 Causes Exostoses 2 Pathway Diagram
Defective PAPSS2 Causes SEMD-PA Pathway antibodies	Defective PAPSS2 Causes SEMD-PA Pathway Diagram

Diseases associated with anti-HS2ST1 antibody

Disease Name	Pubmed Publications
Weight Gain Antibodies	>1 publications with HS2ST1 and Weight Gain
Fibrosis Antibodies	>1 publications with HS2ST1 and Fibrosis
Mammary Neoplasms, Animal Antibodies	>1 publications with HS2ST1 and Mammary Neoplasms, Animal
Neoplasm Metastasis Antibodies	>1 publications with HS2ST1 and Neoplasm Metastasis
Breast Neoplasms Antibodies	>1 publications with HS2ST1 and Breast Neoplasms

Organs/Tissues associated with anti-HS2ST1 antibody

Organ/Tissue Name	Pubmed Publications
Bone Antibodies	>1 publications with HS2ST1 and Bone
Blood Antibodies	>1 publications with HS2ST1 and Blood
Eye Antibodies	>1 publications with HS2ST1 and Eye
Mammary Gland Antibodies	>1 publications with HS2ST1 and Mammary Gland