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PLRG1 Antibody – Rabbit Polyclonal

For Research Use Only. Not for use in diagnostic procedures. Catalog #: MBS416208

This gene encodes a core component of the cell division cycle 5-like (CDC5L) complex. The CDC5L complex is part of the spliceosome and is required for pre-mRNA splicing. The encoded protein plays a critical role in alternative splice site selection.… More details

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Sample Manual Insert View PDF
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Testing Data View PDF
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Technical Datasheet View PDF
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Product Overview

Product Name
PLRG1, Polyclonal Antibody
Full Product Name
Anti-PLRG1 Antibody
Product Gene Name
Clonality
Polyclonal
Host
Rabbit
Species Reactivity
Human. Predicted: Mouse, Rat.
Form/Format
Liquid
Purity/Purification
Affinity purified
Concentration
100ug/100ul (lot specific)
Preparation and Storage
This product is stable for several weeks at 4 degree C as an undiluted liquid. Dilute only prior to immediate use. For extended storage, aliquot contents and freeze at -20 degree C or below. Avoid cycles of freezing and thawing. Expiration date is one (1) year from date of receipt.
Molecular Weight
56,290 Da
OMIM
605961
Storage Buffer
PBS, pH 7.4 with 0.02% Sodium Azide
Immunogen
Rabbit polyclonal PLRG1 (1) antibody was raised against a recombinate human PLRG1 protein 241-451aa (BC020786).
Applications Tested/Suitable for anti-PLRG1 antibody
ELISA (EIA), Western Blot (WB), Immunohistochemistry (IHC)
Application Notes for anti-PLRG1 antibody
ELISA titer: 1:20,000-1:80,000
Western blot analysis: 1:1,000-1:2,000
Immunohistochemistry: 1:100-1:500
Optimal dilutions/concentrations should be determined by the end user.

Testing Data of anti-PLRG1 antibody

Rabbit Anti-PLRG1 Polyclonal Antibody – Cat# MBS416208

Product References and Citations for anti-PLRG1 antibody

(1) Lleres,D., Denegri,M., Biggiogera,M. et al. Direct interaction between hnRNP-M and CDC5L/PLRG1 proteins affects alternative splice site choice. EMBO Rep. 11 (6), 445-451 (2010).

Other Notes

Small volumes of anti-PLRG1 antibody vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.

Searchable Terms for PLRG1 purchase

MBS416208 is an antibody targeting PLRG1. Reactive in Human. Predicted: Mouse, Rat.. Host: Rabbit.

Additional Details

NCBI/Uniprot data below describe general gene information for PLRG1. It may not necessarily be applicable to this product.

NCBI GI #
NCBI GeneID
NCBI Accession #
UniProt Secondary Accession #
UniProt Related Accession #
GenBank Nucleotide #
NCBI Official Full Name
pleiotropic regulator 1 isoform 2
NCBI Official Synonym Full Names
pleiotropic regulator 1
NCBI Official Symbol
PLRG1
NCBI Official Synonym Symbols
Cwc1; PRL1; PRP46; PRPF46; TANGO4
UniProt Protein Name
Pleiotropic regulator 1
Protein Family
UniProt Gene Name
PLRG1
UniProt Entry Name
PLRG1_HUMAN
NCBI Protein Information
pleiotropic regulator 1; pleiotropic regulator 1 (PRL1 homolog, Arabidopsis); transport and golgi organization 4 homolog

UniProt Comments for PLRG1

PLRG1: Component of the PRP19-CDC5L complex that forms an integral part of the spliceosome and is required for activating pre-mRNA splicing. Belongs to the WD repeat PRL1/PRL2 family. 2 isoforms of the human protein are produced by alternative splicing.

Protein type: Transcription, coactivator/corepressor; Spliceosome; RNA splicing

Chromosomal Location of Human Ortholog: 4q31.2-q32.1

Cellular Component: nucleoplasm; DNA replication factor A complex; nuclear speck; nucleus

Molecular Function: protein binding; signal transducer activity; transcription corepressor activity

Biological Process: nuclear mRNA splicing, via spliceosome; RNA splicing; gene expression; signal transduction
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Precautions

All of MyBioSource's Products are for scientific laboratory research purposes and are not for diagnostic, therapeutics, prophylactic or in vivo use. Through your purchase, you expressly represent and warrant to MyBioSource that you will properly test and use any Products purchased from MyBioSource in accordance with industry standards. MyBioSource and its authorized distributors reserve the right to refuse to process any order where we reasonably believe that the intended use will fall outside of our acceptable guidelines.

Disclaimer

While every efforts were made to ensure the accuracy of the information provided in this datasheet, MyBioSource will not be liable for any omissions or errors contained herein. MyBioSource reserves the right to make changes to this datasheet at any time without prior notice.

It is the responsibility of the customer to report product performance issues to MyBioSource within 30 days of receipt of the product. Please visit our Terms & Conditions page for more information.

Product Note

Select online data sheet information is drawn from bioinformatics databases, occasionally resulting in ambiguous or non-relevant product information. It is the responsibility of the customer to review, verify, and evaluate the information to make sure it matches their requirements before purchasing the kit. Our ELISA Kit assays are dynamic research tools and sometimes they may be updated and improved. If the format of this assay is important to you then please request the current manual or contact our technical support team with a presales inquiry before placing an order. We will confirm the current details of the assay. We cannot guarantee the sample manual posted online is the most current manual, it is intended to serve as an example only. Please refer to the instructions For Use provided with the assay kit for precise details.

Product PubMed Publications

Products associated with anti-PLRG1 antibody

 Reference Product  PubMed Publications
 CDC5L antibody  >10 publications with PLRG1 and CDC5L

Diseases associated with anti-PLRG1 antibody

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