AP2M1 Antibody – Rabbit Polyclonal

This gene encodes a subunit of the heterotetrameric coat assembly protein complex 2 (AP2), which belongs to the adaptor complexes medium subunits family. The encoded protein is required for the activity of a vacuolar ATPase, which is responsible for proton pumping occurring in the acidification of endosomes and lysosomes. The encoded protein may also play an important role in regulating the intracellular trafficking and function of CTLA-4 protein. Two transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Jul 2008]

(1) Mizutani,A., Saitoh,M., Imamura,T. et al. Arkadia complexes with clathrin adaptor AP2 and regulates EGF signaling. J. Biochem. 148 (6), 733-741 (2010).

Small volumes of anti-AP2M1 antibody vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.

MBS416216 is an antibody targeting AP2M1. Reactive in Human. Predicted: Mouse, Rat.. Host: Rabbit.