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PDCL Antibody – Rabbit Polyclonal

For Research Use Only. Not for use in diagnostic procedures. Catalog #: MBS416573

MBS416573 is an antibody targeting PDCL. Reactive in Human. Host: Rabbit. Rabbit polyclonal PDCL More details

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Product Documentation
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Sample Manual Insert View PDF
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Testing Data View PDF
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Certificate of Analysis (COA) View PDF
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QC Report View PDF
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Material Safety Data Sheet View PDF
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Technical Datasheet View PDF
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Protocol View PDF

Product Overview

Product Name
PDCL, Polyclonal Antibody
Full Product Name
Anti-PDCL Antibody
Product Gene Name
Clonality
Polyclonal
Host
Rabbit
Species Reactivity
Human
Form/Format
Liquid
Purity/Purification
Affinity purified
Concentration
100ug/100ul (lot specific)
Preparation and Storage
This product is stable for several weeks at 4 degree C as an undiluted liquid. Dilute only prior to immediate use. For extended storage, aliquot contents and freeze at -20 degree C or below. Avoid cycles of freezing and thawing. Expiration date is one (1) year from date of receipt.
Molecular Weight
24,902 Da
OMIM
604421
Storage Buffer
PBS, pH 7.4 with 0.02% Sodium Azide
Immunogen
Raised against a recombinate human PDCL protein 25-489aa (BC017227).
Applications Tested/Suitable for anti-PDCL antibody
Western Blot (WB), Immunohistochemistry (IHC)
Application Notes for anti-PDCL antibody
ELISA titer: 1:20,000-1:80,000
Western blot analysis: 1:500-1:1,000
Immunohistochemistry: 1:100-1:500
Optimal dilutions/concentrations should be determined by the end user.

Western Blot (WB) of anti-PDCL antibody

Rabbit Anti-PDCL Polyclonal Antibody – Cat# MBS416573

Immunohistochemistry (IHC) #2 of anti-PDCL antibody

Rabbit Anti-PDCL Polyclonal Antibody, Immunohistochemistry (IHC) #2 – Cat# MBS416573

Product References and Citations for anti-PDCL antibody

(1) Guzman-Hernandez,M.L., Vazquez-Macias,A., Carretero-Ortega,J., et al. Differential inhibitor of Gbetagamma signaling to AKT and ERK derived from phosducin-like protein: effect on sphingosine 1-phosphate-induced endothelial cell migration and in vitro angiogenesis. J. Biol. Chem. 284 (27), 18334-18346 (2009).

Other Notes

Small volumes of anti-PDCL antibody vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.

Additional Details

NCBI/Uniprot data below describe general gene information for PDCL. It may not necessarily be applicable to this product.

NCBI GI #
NCBI GeneID
NCBI Accession #
UniProt Secondary Accession #
UniProt Related Accession #
NCBI Official Full Name
Homo sapiens phosducin-like, mRNA
NCBI Official Synonym Full Names
phosducin-like
NCBI Official Symbol
PDCL
NCBI Official Synonym Symbols
PhLP
UniProt Protein Name
Phosducin-like protein
UniProt Gene Name
PDCL
UniProt Entry Name
PHLP_HUMAN
NCBI Protein Information
phosducin-like protein

NCBI Summary for PDCL

Phosducin-like protein is a putative modulator of heterotrimeric G proteins. The protein shares extensive amino acid sequence homology with phosducin, a phosphoprotein expressed in retina and pineal gland. Both phosducin-like protein and phosphoducin have been shown to regulate G-protein signaling by binding to the beta-gamma subunits of G proteins. [provided by RefSeq, Jul 2008]
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UniProt Comments for PDCL

PhLP: a member of the phosducin family of G-protein beta-gamma regulators. Shares extensive amino acid sequence homology with phosducin, a phosphoprotein expressed in retina and pineal gland. Both phosducin-like protein and phosphoducin have been shown to regulate G-protein signaling by binding to the beta-gamma subunits of G proteins. Two splice variants have been described.

Protein type: G protein regulator, misc.

Chromosomal Location of Human Ortholog: 9q12-q13

Cellular Component: cytoplasm

Molecular Function: protein binding; receptor signaling protein activity; protein complex binding

Biological Process: visual perception; protein folding; signal transduction; regulation of G-protein coupled receptor protein signaling pathway
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Precautions

All of MyBioSource's Products are for scientific laboratory research purposes and are not for diagnostic, therapeutics, prophylactic or in vivo use. Through your purchase, you expressly represent and warrant to MyBioSource that you will properly test and use any Products purchased from MyBioSource in accordance with industry standards. MyBioSource and its authorized distributors reserve the right to refuse to process any order where we reasonably believe that the intended use will fall outside of our acceptable guidelines.

Disclaimer

While every efforts were made to ensure the accuracy of the information provided in this datasheet, MyBioSource will not be liable for any omissions or errors contained herein. MyBioSource reserves the right to make changes to this datasheet at any time without prior notice.

It is the responsibility of the customer to report product performance issues to MyBioSource within 30 days of receipt of the product. Please visit our Terms & Conditions page for more information.

Product Note

Select online data sheet information is drawn from bioinformatics databases, occasionally resulting in ambiguous or non-relevant product information. It is the responsibility of the customer to review, verify, and evaluate the information to make sure it matches their requirements before purchasing the kit. Our ELISA Kit assays are dynamic research tools and sometimes they may be updated and improved. If the format of this assay is important to you then please request the current manual or contact our technical support team with a presales inquiry before placing an order. We will confirm the current details of the assay. We cannot guarantee the sample manual posted online is the most current manual, it is intended to serve as an example only. Please refer to the instructions For Use provided with the assay kit for precise details.

Product PubMed Publications

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