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MARCKS Antibody – Rabbit Polyclonal

For Research Use Only. Not for use in diagnostic procedures. Catalog #: MBS416856

MBS416856 is an antibody targeting MARCKS. Also known as Anti-MARCKS (Rabbit Polyclonal) Antibody. Host: Rabbit. More details

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Product Documentation
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Sample Manual Insert View PDF
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Testing Data View PDF
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Certificate of Analysis (COA) View PDF
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QC Report View PDF
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Material Safety Data Sheet View PDF
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Technical Datasheet View PDF
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Protocol View PDF

Product Overview

Product Name
MARCKS, Polyclonal Antibody
Full Product Name
Anti-MARCKS (Rabbit Polyclonal) Antibody
Product Gene Name
Product Synonym Names
Anti-MARCKS (Rabbit Polyclonal)
Clonality
Polyclonal
Host
Rabbit
Form/Format
Liquid
Concentration
100ug/100ul (lot specific)
Specificity
Myristoylated alanine rich C kinase substrate.
Preparation and Storage
This product is stable for several weeks at 4 degree C as an undiluted liquid. Dilute only prior to immediate use. For extended storage, aliquot contents and freeze at -20 degree C or below. Avoid cycles of freezing and thawing. Expiration date is one (1) year from date of receipt.
Molecular Weight
31,555 Da
Chromosome Location
Chromosome: 6; NC_000006.11 (114178527..114184652). Location: 6q22.2
OMIM
177061
3D Structure
ModBase 3D Structure for P29966
Immunogen
Full length recombinant MARCKS (Myristoylated alanine rich C Kinase substrate) expressed in and purified from E. coli.
Storage Buffer
PBS, pH 7.4 with 0.05% sodium azide.

Product Categories/Family for anti-MARCKS antibody

Applications Tested/Suitable for anti-MARCKS antibody
Western Blot (WB), Immunocytochemistry (ICC), Immunofluorescence (IF)
Application Notes for anti-MARCKS antibody
Immunofluorescence: 1:250 to 1:500, for ABC or other enzyme linked immunocytochemical procedures: 1:500. Western blots: 1:1000.

Western Blot (WB) of anti-MARCKS antibody

Rabbit Anti-MARCKS Polyclonal Antibody – Cat# MBS416856

Other Notes

Small volumes of anti-MARCKS antibody vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.

Additional Details

NCBI/Uniprot data below describe general gene information for MARCKS. It may not necessarily be applicable to this product.

NCBI GI #
NCBI GeneID
NCBI Accession #
UniProt Primary Accession #
UniProt Secondary Accession #
UniProt Related Accession #
GenBank Nucleotide #
NCBI Official Full Name
myristoylated alanine-rich C-kinase substrate
NCBI Official Synonym Full Names
myristoylated alanine-rich protein kinase C substrate
NCBI Official Symbol
MARCKS
NCBI Official Synonym Symbols
MACS; 80K-L; PKCSL; PRKCSL
UniProt Protein Name
Myristoylated alanine-rich C-kinase substrate
UniProt Synonym Protein Names
Protein kinase C substrate, 80 kDa protein, light chain; 80K-L protein; PKCSL
UniProt Gene Name
MARCKS
UniProt Synonym Gene Names
MACS; PRKCSL; MARCKS; 80K-L protein; PKCSL
UniProt Entry Name
MARCS_HUMAN
NCBI Protein Information
myristoylated alanine-rich C-kinase substrate; phosphomyristin; protein kinase C substrate, 80 kDa protein, light chain; myristoylated alanine-rich protein kinase C substrate (MARCKS, 80K-L)

NCBI Summary for MARCKS

The protein encoded by this gene is a substrate for protein kinase C. It is localized to the plasma membrane and is an actin filament crosslinking protein. Phosphorylation by protein kinase C or binding to calcium-calmodulin inhibits its association with actin and with the plasma membrane, leading to its presence in the cytoplasm. The protein is thought to be involved in cell motility, phagocytosis, membrane trafficking and mitogenesis. [provided by RefSeq, Jul 2008]
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UniProt Comments for MARCKS

Function: MARCKS is the most prominent cellular substrate for protein kinase C. This protein binds calmodulin, actin, and synapsin. MARCKS is a filamentous (F) actin cross-linking protein.

Subcellular location: Cytoplasm › cytoskeleton

Probable. Membrane; Lipid-anchor

By similarity.

Post-translational modification: Phosphorylation by PKC displaces MARCKS from the membrane. It also inhibits the F-actin cross-linking activity.

Sequence similarities: Belongs to the MARCKS family.
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Precautions

All of MyBioSource's Products are for scientific laboratory research purposes and are not for diagnostic, therapeutics, prophylactic or in vivo use. Through your purchase, you expressly represent and warrant to MyBioSource that you will properly test and use any Products purchased from MyBioSource in accordance with industry standards. MyBioSource and its authorized distributors reserve the right to refuse to process any order where we reasonably believe that the intended use will fall outside of our acceptable guidelines.

Disclaimer

While every efforts were made to ensure the accuracy of the information provided in this datasheet, MyBioSource will not be liable for any omissions or errors contained herein. MyBioSource reserves the right to make changes to this datasheet at any time without prior notice.

It is the responsibility of the customer to report product performance issues to MyBioSource within 30 days of receipt of the product. Please visit our Terms & Conditions page for more information.

Product Note

Select online data sheet information is drawn from bioinformatics databases, occasionally resulting in ambiguous or non-relevant product information. It is the responsibility of the customer to review, verify, and evaluate the information to make sure it matches their requirements before purchasing the kit. Our ELISA Kit assays are dynamic research tools and sometimes they may be updated and improved. If the format of this assay is important to you then please request the current manual or contact our technical support team with a presales inquiry before placing an order. We will confirm the current details of the assay. We cannot guarantee the sample manual posted online is the most current manual, it is intended to serve as an example only. Please refer to the instructions For Use provided with the assay kit for precise details.

Product PubMed Publications

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