Rabbit Anti-ARID3A Polyclonal Antibody – Cat# MBS416908

ARID3A Antibody – Rabbit Polyclonal

Name: ARID3A Antibody; Polyclonal; Rabbit; Human/Mouse/Rat-Reactive; MyBioSource
Brand: MyBioSource
SKU: MBS416908
Price: 335 USD
Availability: InStock
Rating: 5 (10 reviews)

For Research Use Only. Not for use in diagnostic procedures. Catalog #: MBS416908

This gene encodes a member of the ARID (AT-rich interaction domain) family of DNA binding proteins. It was found by homology to the Drosophila dead ringer gene, which is important for normal embryogenesis. Other ARID family members have roles in embryonic… More details

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Product Documentation

Sample Manual Insert View PDF

Testing Data View PDF

Certificate of Analysis (COA) View PDF

QC Report View PDF

Material Safety Data Sheet View PDF

Technical Datasheet View PDF

Protocol View PDF

Product Overview

Product Name

ARID3A, Polyclonal Antibody

Full Product Name

Anti-ARID3A Antibody

Product Gene Name

anti-ARID3A antibody

Clonality

Polyclonal

Host

Rabbit

Species Reactivity

Human. Predicted: Mouse, Rat

Form/Format

Liquid

Purity/Purification

Affinity purified

Concentration

100ug/100ul (lot specific)

Preparation and Storage

This product is stable for several weeks at 4 degree C as an undiluted liquid. Dilute only prior to immediate use. For extended storage, aliquot contents and freeze at -20 degree C or below. Avoid cycles of freezing and thawing. Expiration date is one (1) year from date of receipt.

Molecular Weight

62,889 Da

OMIM

603265

Storage Buffer

PBS, pH 7.4 with 0.02% sodium azide.

Immunogen

Rabbit polyclonal ARID3A(1) antibody was raised against a recombinate human ARID3A protein 356-527aa (BC060828).

Applications Tested/Suitable for anti-ARID3A antibody

ELISA (EIA), Western Blot (WB)

Application Notes for anti-ARID3A antibody

ELISA titer: 1:20,000-1:80,000
Western blot analysis: 1:500-1:1,000
Optimal dilutions/concentrations should be determined by the end user

Product References and Citations for anti-ARID3A antibody

(1) Puissegur,M.P., Eichner,R., Quelen,C., et al. B-cell regulator of immunoglobulin heavy-chain transcription (Bright)/ARID3a is a direct target of the oncomir microRNA-125b in progenitor B-cells. Leukemia 26 (10), 2224-2232 (2012)

Other Notes

Small volumes of anti-ARID3A antibody vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.

Searchable Terms for ARID3A purchase

MBS416908 is an antibody targeting ARID3A. Reactive in Human. Predicted: Mouse, Rat. Host: Rabbit.

Additional Details

NCBI/Uniprot data below describe general gene information for ARID3A. It may not necessarily be applicable to this product.

NCBI GI #

38173799

NCBI GeneID

1820

NCBI Accession #

BC060828

UniProt Secondary Accession #

Q5I858; Q6P9C6; Q8IZA7; Q8N4Z3

UniProt Related Accession #

Q99856

NCBI Official Full Name

Homo sapiens AT rich interactive domain 3A (BRIGHT-like), mRNA

NCBI Official Synonym Full Names

AT rich interactive domain 3A (BRIGHT-like)

NCBI Official Symbol

ARID3A

NCBI Official Synonym Symbols

DRIL1; DRIL3; BRIGHT; E2FBP1

UniProt Protein Name

AT-rich interactive domain-containing protein 3A

UniProt Synonym Protein Names

B-cell regulator of IgH transcription; Bright; Dead ringer-like protein 1; E2F-binding protein 1

Protein Family

AT-rich interactive domain-containing protein

UniProt Gene Name

ARID3A

UniProt Entry Name

ARI3A_HUMAN

NCBI Protein Information

AT-rich interactive domain-containing protein 3A; ARID domain-containing 3A; ARID domain-containing protein 3A; AT rich interactive domain 3A (BRIGHT- like) protein; B-cell regulator of IgH transcription; E2F-binding protein 1; dead ringer-like 1; dead ringer-like protein 1

UniProt Comments for ARID3A

Bright: a member of the ARID (AT-rich interaction domain) family of transcription factors. It was found by its homology to the Drosophila dead ringer protein, which is important for normal embryogenesis. Binds a VH promoter proximal site necessary for induced mu-heavy-chain transcription. Binds the minor groove of a restricted ATC sequence that is sufficient for nuclear matrix association. This sequence motif is present in matrix-associating regions (MARS) proximal to the promoter and flanking E mu. Activates E mu-driven transcription by binding these sites. Contributes to localized control of accessibility and therefore nonrandom gene use during V(D)J recombination.

Protein type: Transcription factor

Chromosomal Location of Human Ortholog: 19p13.3

Cellular Component: nucleoplasm; Golgi apparatus; cytoplasm; nucleolus; lipid raft

Molecular Function: protein binding; protein homodimerization activity; chromatin binding

Biological Process: transcription, DNA-dependent; positive regulation of transcription from RNA polymerase II promoter

Research Articles on ARID3A

1. Systemic lupus erythematosus (SLE) patients had increased ARID3a+ B cells compared to healthy controls. ARID3a was not expressed in naive B cells of controls, but was abundant in SLE patients. Number of ARID3a+ B cells correlated with disease activity.

Precautions

All of MyBioSource's Products are for scientific laboratory research purposes and are not for diagnostic, therapeutics, prophylactic or in vivo use. Through your purchase, you expressly represent and warrant to MyBioSource that you will properly test and use any Products purchased from MyBioSource in accordance with industry standards. MyBioSource and its authorized distributors reserve the right to refuse to process any order where we reasonably believe that the intended use will fall outside of our acceptable guidelines.

Disclaimer

While every efforts were made to ensure the accuracy of the information provided in this datasheet, MyBioSource will not be liable for any omissions or errors contained herein. MyBioSource reserves the right to make changes to this datasheet at any time without prior notice.

It is the responsibility of the customer to report product performance issues to MyBioSource within 30 days of receipt of the product. Please visit our Terms & Conditions page for more information.

Product Note

Select online data sheet information is drawn from bioinformatics databases, occasionally resulting in ambiguous or non-relevant product information. It is the responsibility of the customer to review, verify, and evaluate the information to make sure it matches their requirements before purchasing the kit. Our ELISA Kit assays are dynamic research tools and sometimes they may be updated and improved. If the format of this assay is important to you then please request the current manual or contact our technical support team with a presales inquiry before placing an order. We will confirm the current details of the assay. We cannot guarantee the sample manual posted online is the most current manual, it is intended to serve as an example only. Please refer to the instructions For Use provided with the assay kit for precise details.

Product PubMed Publications

Products associated with anti-ARID3A antibody

Reference Product	PubMed Publications
BTK antibody	>6 publications with ARID3A and BTK
PML antibody	>4 publications with ARID3A and PML
SP100 antibody	>1 publications with ARID3A and SP100
SUMO1 antibody	>1 publications with ARID3A and SUMO1
SP140 antibody	>1 publications with ARID3A and SP140
TP53 antibody	>1 publications with ARID3A and TP53

Pathways associated with anti-ARID3A antibody

Products by Pathway	Pathway Diagram
Direct P53 Effectors Pathway antibodies	Direct P53 Effectors Pathway Diagram

Diseases associated with anti-ARID3A antibody

Disease Name	Pubmed Publications
Fibrosis Antibodies	>1 publications with ARID3A and Fibrosis
Translocation, Genetic Antibodies	>1 publications with ARID3A and Translocation, Genetic
Brain Diseases Antibodies	>1 publications with ARID3A and Brain Diseases
Kidney Diseases Antibodies	>1 publications with ARID3A and Kidney Diseases

Organs/Tissues associated with anti-ARID3A antibody

Organ/Tissue Name	Pubmed Publications
Bone Antibodies	>4 publications with ARID3A and Bone
Liver Antibodies	>2 publications with ARID3A and Liver
Lymph Node Antibodies	>2 publications with ARID3A and Lymph Node
Embryonic Tissue Antibodies	>2 publications with ARID3A and Embryonic Tissue
Ovary Antibodies	>1 publications with ARID3A and Ovary
Kidney Antibodies	>1 publications with ARID3A and Kidney
Placenta Antibodies	>1 publications with ARID3A and Placenta