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VASP Antibody – Rabbit Polyclonal

For Research Use Only. Not for use in diagnostic procedures. Catalog #: MBS417174

Vasodilator-stimulated phosphoprotein (VASP) is a member of the Ena-VASP protein family. Ena-VASP family members contain an EHV1 N-terminal domain that binds proteins containing E/DFPPPPXD/E motifs and targets Ena-VASP proteins to focal adhesions. In the… More details

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Technical Datasheet View PDF
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Product Overview

Product Name
VASP, Polyclonal Antibody
Full Product Name
Anti-VASP Antibody
Product Gene Name
anti-VASP antibody
Clonality
Polyclonal
Host
Rabbit
Species Reactivity
Human, Mouse, Rat
Form/Format
Liquid
Purity/Purification
The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
Concentration
1ug/ul (lot specific)
Specificity
VASP (Ab-157) antibody detects endogenous levels of total VASP protein.
Preparation and Storage
This product is stable for several weeks at 4 degree C as an undiluted liquid. Dilute only prior to immediate use. For extended storage, aliquot contents and freeze at -20 degree C or below. Avoid cycles of freezing and thawing. Expiration date is one (1) year from date of receipt.
Molecular Weight
39,830 Da
OMIM
601703
Storage Buffer
phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol.
Immunogen
The antiserum was produced against synthesized non-phosphopeptide derived from human VASP around the phosphorylation site of serine 157 (R-V-SP-N-A).
Applications Tested/Suitable for anti-VASP antibody
Western Blot (WB)
Application Notes for anti-VASP antibody
WB: 1:500~1:1000

Product References and Citations for anti-VASP antibody

Zhao WM, et al. (2001) EMBO J 20(9): 2315-2325.
Millard TH, et al. (2005) EMBO J 24(2): 240-250.
Khnel K, et al. (2004) Proc Natl Acad Sci U S A 101(49): 17027-17032.
Haffner C, et al. (1995) EMBO J 14(1): 19-27.
Ramesh N, et al. (1997) Proc Natl Acad Sci U S A 94(26): 14671-14676.

Other Notes

Small volumes of anti-VASP antibody vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.

Searchable Terms for VASP purchase

MBS417174 is an antibody targeting VASP. Reactive in Human, Mouse, Rat. Host: Rabbit.

Additional Details

NCBI/Uniprot data below describe general gene information for VASP. It may not necessarily be applicable to this product.

NCBI GI #
4507869
NCBI GeneID
7408
NCBI Accession #
NP_003361.1
UniProt Secondary Accession #
Q6PIZ1; Q93035; B2RBT9
UniProt Related Accession #
P50552
GenBank Nucleotide #
NM_003370.3
NCBI Official Full Name
vasodilator-stimulated phosphoprotein
NCBI Official Synonym Full Names
vasodilator-stimulated phosphoprotein
NCBI Official Symbol
VASP
UniProt Protein Name
Vasodilator-stimulated phosphoprotein
Protein Family
Protein
UniProt Gene Name
VASP
UniProt Entry Name
VASP_HUMAN
NCBI Protein Information
vasodilator-stimulated phosphoprotein

UniProt Comments for VASP

VASP: vasodilator-stimulated phosphoprotein. Actin- and profilin-binding microfilament-associated protein. The phosphorylation of VASP is dynamically regulated by cellular adhesion to extracellular matrix.

Protein type: Motility/polarity/chemotaxis; Cytoskeletal

Chromosomal Location of Human Ortholog: 19q13.32

Cellular Component: filopodium membrane; tight junction; focal adhesion; cytoplasm; plasma membrane; cytosol; actin cytoskeleton

Molecular Function: protein binding; actin binding; SH3 domain binding; profilin binding

Biological Process: axon guidance; positive regulation of actin filament polymerization; actin polymerization and/or depolymerization; neural tube closure; T cell receptor signaling pathway; protein homotetramerization
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Research Articles on VASP

1. VASP reconstitution of actin-based motility depends on the recruitment of F-actin seeds from the solution produced by cofilin

Precautions

All of MyBioSource's Products are for scientific laboratory research purposes and are not for diagnostic, therapeutics, prophylactic or in vivo use. Through your purchase, you expressly represent and warrant to MyBioSource that you will properly test and use any Products purchased from MyBioSource in accordance with industry standards. MyBioSource and its authorized distributors reserve the right to refuse to process any order where we reasonably believe that the intended use will fall outside of our acceptable guidelines.

Disclaimer

While every efforts were made to ensure the accuracy of the information provided in this datasheet, MyBioSource will not be liable for any omissions or errors contained herein. MyBioSource reserves the right to make changes to this datasheet at any time without prior notice.

It is the responsibility of the customer to report product performance issues to MyBioSource within 30 days of receipt of the product. Please visit our Terms & Conditions page for more information.

Product Note

Select online data sheet information is drawn from bioinformatics databases, occasionally resulting in ambiguous or non-relevant product information. It is the responsibility of the customer to review, verify, and evaluate the information to make sure it matches their requirements before purchasing the kit. Our ELISA Kit assays are dynamic research tools and sometimes they may be updated and improved. If the format of this assay is important to you then please request the current manual or contact our technical support team with a presales inquiry before placing an order. We will confirm the current details of the assay. We cannot guarantee the sample manual posted online is the most current manual, it is intended to serve as an example only. Please refer to the instructions For Use provided with the assay kit for precise details.

Product PubMed Publications

Products associated with anti-VASP antibody

 Reference Product  PubMed Publications
 ZYX antibody  >34 publications with VASP and ZYX
 PFN1 antibody  >24 publications with VASP and PFN1
 FYB antibody  >9 publications with VASP and FYB
 RAPH1 antibody  >7 publications with VASP and RAPH1
 LPP antibody  >7 publications with VASP and LPP
 PRKG1 antibody  >6 publications with VASP and PRKG1
 PFN2 antibody  >5 publications with VASP and PFN2
 CXCR2 antibody  >1 publications with VASP and CXCR2

Pathways associated with anti-VASP antibody

 Products by Pathway  Pathway Diagram
 Adaptive Immune System Pathway antibodies  Adaptive Immune System Pathway Diagram
 Axon Guidance Pathway antibodies  Axon Guidance Pathway Diagram
 Cell Junction Organization Pathway antibodies  Cell Junction Organization Pathway Diagram
 Cell-Cell Communication Pathway antibodies  Cell-Cell Communication Pathway Diagram
 Cell-extracellular Matrix Interactions Pathway antibodies  Cell-extracellular Matrix Interactions Pathway Diagram
 Developmental Biology Pathway antibodies  Developmental Biology Pathway Diagram
 E-cadherin Signaling In Keratinocytes Pathway antibodies  E-cadherin Signaling In Keratinocytes Pathway Diagram
 Fc Gamma R-mediated Phagocytosis Pathway antibodies  Fc Gamma R-mediated Phagocytosis Pathway Diagram
 Fc Gamma R-mediated Phagocytosis Pathway antibodies  Fc Gamma R-mediated Phagocytosis Pathway Diagram
 Focal Adhesion Pathway antibodies  Focal Adhesion Pathway Diagram

Diseases associated with anti-VASP antibody

 Disease Name  Pubmed Publications
 Thrombosis Antibodies  >80 publications with VASP and Thrombosis
 Pain Antibodies  >68 publications with VASP and Pain
 Disease Models, Animal Antibodies  >41 publications with VASP and Disease Models, Animal
 Inflammation Antibodies  >34 publications with VASP and Inflammation
 Nervous System Diseases Antibodies  >32 publications with VASP and Nervous System Diseases
 Hemorrhage Antibodies  >19 publications with VASP and Hemorrhage
 Hypertension Antibodies  >19 publications with VASP and Hypertension
 Atherosclerosis Antibodies  >16 publications with VASP and Atherosclerosis
 Hypertrophy Antibodies  >15 publications with VASP and Hypertrophy
 Breast Neoplasms Antibodies  >15 publications with VASP and Breast Neoplasms

Organs/Tissues associated with anti-VASP antibody

 Organ/Tissue Name  Pubmed Publications
 Blood Antibodies  >400 publications with VASP and Blood
 Vascular Antibodies  >165 publications with VASP and Vascular
 Muscle Antibodies  >94 publications with VASP and Muscle
 Brain Antibodies  >70 publications with VASP and Brain
 Embryonic Tissue Antibodies  >39 publications with VASP and Embryonic Tissue
 Kidney Antibodies  >34 publications with VASP and Kidney
 Lung Antibodies  >32 publications with VASP and Lung
 Liver Antibodies  >22 publications with VASP and Liver
 Bone Antibodies  >16 publications with VASP and Bone
 Eye Antibodies  >11 publications with VASP and Eye
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