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FUT9 Antibody – Rabbit Polyclonal

For Research Use Only. Not for use in diagnostic procedures. Catalog #: MBS417282

This gene belongs to the glycosyltransferase family. It is localized to the golgi, and catalyzes the last step in the biosynthesis of Lewis X (LeX) antigen, the addition of a fucose to precursor polysaccharides. This protein is one of the few… More details

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Product Overview

Product Name
FUT9, Polyclonal Antibody
Full Product Name
Anti-FUT9 Antibody
Product Gene Name
anti-FUT9 antibody
Clonality
Polyclonal
Host
Rabbit
Species Reactivity
Human. Predicted: Mouse, Rat. Not yet tested in other species.
Form/Format
Liquid
Purity/Purification
Affinity purified
Concentration
100ug/100ul (lot specific)
Preparation and Storage
This product is stable for several weeks at 4 degree C as an undiluted liquid. Dilute only prior to immediate use. For extended storage, aliquot contents and freeze at -20 degree C or below. Avoid cycles of freezing and thawing. Expiration date is one (1) year from date of receipt.
Molecular Weight
42,071 Da
OMIM
606865
Storage Buffer
PBS, pH 7.4 with 0.02% sodium azide.
Immunogen
Rabbit polyclonal FUT9(1) antibody was raised against a recombinate human FUT9 protein 166-354 aa(BC036101).
Applications Tested/Suitable for anti-FUT9 antibody
ELISA (EIA), Western Blot (WB), Immunohistochemistry (IHC)
Application Notes for anti-FUT9 antibody
ELISA titer: 1:20,000-1:80,000
Western blot analysis: 1:200-1:1,000
Immunohistochemistry: 1:100-1:500
Optimal dilutions/concentrations should be determined by the end user.

Product References and Citations for anti-FUT9 antibody

(1)Buffone,A. Jr., Mondal,N., Gupta,R.,et al.Silencing alpha1,3-fucosyltransferases in human leukocytes reveals a role for FUT9 enzyme during E-selectin-mediated cell adhesion. J. Biol. Chem. 288 (3), 1620-1633(2013)

Other Notes

Small volumes of anti-FUT9 antibody vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.

Searchable Terms for FUT9 purchase

MBS417282 is an antibody targeting FUT9. Reactive in Human. Predicted: Mouse, Rat. Not yet tested in other species.. Host: Rabbit.

Additional Details

NCBI/Uniprot data below describe general gene information for FUT9. It may not necessarily be applicable to this product.

NCBI GI #
23273584
NCBI GeneID
10690
NCBI Accession #
BC036101
UniProt Secondary Accession #
Q5T0W4
UniProt Related Accession #
Q9Y231
NCBI Official Full Name
Homo sapiens fucosyltransferase 9 (alpha (1,3) fucosyltransferase), mRNA
NCBI Official Synonym Full Names
fucosyltransferase 9 (alpha (1,3) fucosyltransferase)
NCBI Official Symbol
FUT9
NCBI Official Synonym Symbols
Fuc-TIX
UniProt Protein Name
Alpha-(1,3)-fucosyltransferase 9
UniProt Synonym Protein Names
Fucosyltransferase 9; Fucosyltransferase IX; Fuc-TIX; FucT-IX; Galactoside 3-L-fucosyltransferase
Protein Family
Alpha-(1,3)-fucosyltransferase
UniProt Gene Name
FUT9
UniProt Entry Name
FUT9_HUMAN
NCBI Protein Information
alpha-(1,3)-fucosyltransferase 9; alpha-(1,3)-fucosyltransferase 9; fucT-IX; fucosyltransferase IX; galactoside 3-L-fucosyltransferase

NCBI Summary for FUT9

The protein encoded by this gene belongs to the glycosyltransferase family. It is localized to the golgi, and catalyzes the last step in the biosynthesis of Lewis X (LeX) antigen, the addition of a fucose to precursor polysaccharides. This protein is one of the few fucosyltransferases that synthesizes the LeX oligosaccharide (CD15) expressed in the organ buds progressing in mesenchyma during embryogenesis. It is also responsible for the expression of CD15 in mature granulocytes. A common haplotype of this gene has also been associated with susceptibility to placental malaria infection. [provided by RefSeq, Nov 2011]
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UniProt Comments for FUT9

FUT9: Transfers a fucose to lacto-N-neotetraose but not to either alpha2,3-sialyl lacto-N-neotetraose or lacto-N-tetraose. Can catalyze the last step in the biosynthesis of Lewis antigen, the addition of a fucose to precursor polysaccharides. Belongs to the glycosyltransferase 10 family.

Protein type: Glycan Metabolism - glycosphingolipid biosynthesis - globo series; EC 2.4.1.-; Glycan Metabolism - glycosphingolipid biosynthesis - lacto and neolacto series; Membrane protein, integral; Transferase

Chromosomal Location of Human Ortholog: 6q16

Cellular Component: Golgi apparatus; integral to membrane

Molecular Function: alpha(1,3)-fucosyltransferase activity; fucosyltransferase activity

Biological Process: nervous system development; carbohydrate metabolic process; protein amino acid glycosylation; L-fucose catabolic process
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Research Articles on FUT9

1. N-glycosylation of human alpha1,3-fucosyltransferase IX is required for enzyme stability and activity.

Precautions

All of MyBioSource's Products are for scientific laboratory research purposes and are not for diagnostic, therapeutics, prophylactic or in vivo use. Through your purchase, you expressly represent and warrant to MyBioSource that you will properly test and use any Products purchased from MyBioSource in accordance with industry standards. MyBioSource and its authorized distributors reserve the right to refuse to process any order where we reasonably believe that the intended use will fall outside of our acceptable guidelines.

Disclaimer

While every efforts were made to ensure the accuracy of the information provided in this datasheet, MyBioSource will not be liable for any omissions or errors contained herein. MyBioSource reserves the right to make changes to this datasheet at any time without prior notice.

It is the responsibility of the customer to report product performance issues to MyBioSource within 30 days of receipt of the product. Please visit our Terms & Conditions page for more information.

Product Note

Select online data sheet information is drawn from bioinformatics databases, occasionally resulting in ambiguous or non-relevant product information. It is the responsibility of the customer to review, verify, and evaluate the information to make sure it matches their requirements before purchasing the kit. Our ELISA Kit assays are dynamic research tools and sometimes they may be updated and improved. If the format of this assay is important to you then please request the current manual or contact our technical support team with a presales inquiry before placing an order. We will confirm the current details of the assay. We cannot guarantee the sample manual posted online is the most current manual, it is intended to serve as an example only. Please refer to the instructions For Use provided with the assay kit for precise details.

Product PubMed Publications

Products associated with anti-FUT9 antibody

 Reference Product  PubMed Publications
 FUT4 antibody  >16 publications with FUT9 and FUT4
 FUT3 antibody  >5 publications with FUT9 and FUT3
 FUT6 antibody  >3 publications with FUT9 and FUT6
 FUT5 antibody  >3 publications with FUT9 and FUT5
 FUT1 antibody  >3 publications with FUT9 and FUT1
 FUT2 antibody  >2 publications with FUT9 and FUT2
 B4GALT1 antibody  >1 publications with FUT9 and B4GALT1

Pathways associated with anti-FUT9 antibody

 Products by Pathway  Pathway Diagram
 Glycosphingolipid Biosynthesis - Globo Series Pathway antibodies  Glycosphingolipid Biosynthesis - Globo Series Pathway Diagram
 Glycosphingolipid Biosynthesis - Globo Series Pathway antibodies  Glycosphingolipid Biosynthesis - Globo Series Pathway Diagram
 Glycosphingolipid Biosynthesis - Lacto And Neolacto Series Pathway antibodies  Glycosphingolipid Biosynthesis - Lacto And Neolacto Series Pathway Diagram
 Glycosphingolipid Biosynthesis - Lacto And Neolacto Series Pathway antibodies  Glycosphingolipid Biosynthesis - Lacto And Neolacto Series Pathway Diagram
 Metabolic Pathways antibodies  Metabolic Pathways Diagram
 Other Types Of O-glycan Biosynthesis Pathway antibodies  Other Types Of O-glycan Biosynthesis Pathway Diagram
 Other Types Of O-glycan Biosynthesis Pathway antibodies  Other Types Of O-glycan Biosynthesis Pathway Diagram
 Terminal O-glycans Residues Modification Pathway antibodies  Terminal O-glycans Residues Modification Pathway Diagram
 Terminal O-glycans Residues Modification Pathway antibodies  Terminal O-glycans Residues Modification Pathway Diagram

Diseases associated with anti-FUT9 antibody

 Disease Name  Pubmed Publications
 Inflammation Antibodies  >3 publications with FUT9 and Inflammation
 Memory Disorders Antibodies  >1 publications with FUT9 and Memory Disorders
 Ovarian Neoplasms Antibodies  >1 publications with FUT9 and Ovarian Neoplasms
 Learning Disorders Antibodies  >1 publications with FUT9 and Learning Disorders
 Weight Gain Antibodies  >1 publications with FUT9 and Weight Gain
 Ovarian Diseases Antibodies  >1 publications with FUT9 and Ovarian Diseases

Organs/Tissues associated with anti-FUT9 antibody

 Organ/Tissue Name  Pubmed Publications
 Brain Antibodies  >8 publications with FUT9 and Brain
 Embryonic Tissue Antibodies  >2 publications with FUT9 and Embryonic Tissue
 Kidney Antibodies  >1 publications with FUT9 and Kidney
 Stomach Antibodies  >1 publications with FUT9 and Stomach
 Eye Antibodies  >1 publications with FUT9 and Eye
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