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DNAJC5 Antibody – Rabbit

For Research Use Only. Not for use in diagnostic procedures. Catalog #: MBS004173

MBS004173 is an antibody targeting DNAJC5. Also known as Rabbit DNAJC5 Antibody. Reactive in Human, mouse, rat. Host: Rabbit. More details

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Product Documentation
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Sample Manual Insert View PDF
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Testing Data View PDF
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Certificate of Analysis (COA) View PDF
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QC Report View PDF
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Material Safety Data Sheet View PDF
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Technical Datasheet View PDF
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Protocol View PDF

Product Overview

Product Name
DNAJC5, Antibody
Full Product Name
Rabbit DNAJC5 Antibody
Product Gene Name
Host
Rabbit
Species Reactivity
Human, mouse, rat
Form/Format
Phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol
Concentration
1 mg/ml (lot specific)
Molecular Weight
22,149 Da
Chromosome Location
Chromosome: 20; NC_000020.10 (62526455..62567384). Location: 20q13.33
OMIM
162350
3D Structure
ModBase 3D Structure for Q9H3Z4
Applications Tested/Suitable for anti-DNAJC5 antibody
ELISA (EIA), Western Blot (WB)

Other Notes

Small volumes of anti-DNAJC5 antibody vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.

Additional Details

NCBI/Uniprot data below describe general gene information for DNAJC5. It may not necessarily be applicable to this product.

NCBI GI #
NCBI GeneID
NCBI Accession #
UniProt Primary Accession #
UniProt Secondary Accession #
UniProt Related Accession #
GenBank Nucleotide #
NCBI Official Full Name
dnaJ homolog subfamily C member 5
NCBI Official Synonym Full Names
DnaJ (Hsp40) homolog, subfamily C, member 5
NCBI Official Symbol
DNAJC5
NCBI Official Synonym Symbols
CSP; NCL; CLN4; CLN4B; DNAJC5A
UniProt Protein Name
DnaJ homolog subfamily C member 5
UniProt Synonym Protein Names
Cysteine string protein
UniProt Gene Name
DNAJC5
UniProt Synonym Gene Names
CSP; CSP
UniProt Entry Name
DNJC5_HUMAN
NCBI Protein Information
dnaJ homolog subfamily C member 5; cysteine string protein alpha

NCBI Summary for DNAJC5

This gene is a member of the J protein family. J proteins function in many cellular processes by regulating the ATPase activity of 70 kDa heat shock proteins. The encoded protein plays a role in membrane trafficking and protein folding, and has been shown to have anti-neurodegenerative properties. The encoded protein is known to play a role in cystic fibrosis and Huntington's disease. A pseudogene of this gene is located on the short arm of chromosome 8. [provided by RefSeq, Nov 2010]
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UniProt Comments for DNAJC5

DNAJC5: a cysteine string protein that inhibits N-type calcium channels which is blocked by huntingtin mutants. May have an important role in presynaptic function. May be involved in calcium-dependent neurotransmitter release at nerve endings. Modulates the maturation of cystic fibrosis transmembrane conductance regulator. Two splice-variant isoforms have been described.

Protein type: Vesicle

Chromosomal Location of Human Ortholog: 20q13.33

Cellular Component: synaptic vesicle; membrane; mitochondrion; lysosomal membrane; plasma membrane; melanosome

Molecular Function: ATP-dependent protein binding; glycoprotein binding

Biological Process: regulated secretory pathway; synaptic transmission; synaptic vesicle exocytosis; exocytosis; neurotransmitter secretion; negative regulation of neuron apoptosis
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Precautions

All of MyBioSource's Products are for scientific laboratory research purposes and are not for diagnostic, therapeutics, prophylactic or in vivo use. Through your purchase, you expressly represent and warrant to MyBioSource that you will properly test and use any Products purchased from MyBioSource in accordance with industry standards. MyBioSource and its authorized distributors reserve the right to refuse to process any order where we reasonably believe that the intended use will fall outside of our acceptable guidelines.

Disclaimer

While every efforts were made to ensure the accuracy of the information provided in this datasheet, MyBioSource will not be liable for any omissions or errors contained herein. MyBioSource reserves the right to make changes to this datasheet at any time without prior notice.

It is the responsibility of the customer to report product performance issues to MyBioSource within 30 days of receipt of the product. Please visit our Terms & Conditions page for more information.

Product Note

Select online data sheet information is drawn from bioinformatics databases, occasionally resulting in ambiguous or non-relevant product information. It is the responsibility of the customer to review, verify, and evaluate the information to make sure it matches their requirements before purchasing the kit. Our ELISA Kit assays are dynamic research tools and sometimes they may be updated and improved. If the format of this assay is important to you then please request the current manual or contact our technical support team with a presales inquiry before placing an order. We will confirm the current details of the assay. We cannot guarantee the sample manual posted online is the most current manual, it is intended to serve as an example only. Please refer to the instructions For Use provided with the assay kit for precise details.

Product PubMed Publications

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