• Call +1.858.633.0165 or Fax +1.858.633.0166 or Contact Us

Cnpase (CNP) Antibody – Rabbit Polyclonal

For Research Use Only. Not for use in diagnostic procedures. Catalog #: MBS2400358

CNP Antibody, CNP1 Antibody, CNPase Antibody, Phosphodiesterase CNP Antibody Description: May participate in RNA metabolism in the myelinating cell, CNP is the third most abundant protein in central nervous system myelin. More details

$650 / 0.05 mL +1 FREE 8GB USB
Product Documentation
PDF
Sample Manual Insert View PDF
PDF
Testing Data View PDF
PDF
Certificate of Analysis (COA) View PDF
PDF
QC Report View PDF
PDF
Material Safety Data Sheet View PDF
PDF
Technical Datasheet View PDF
PDF
Protocol View PDF

Product Overview

Online Datasheet in PDF
Product Name
CNPase, Polyclonal Antibody
Full Product Name
Anti-CNPase Antibody IHC-plus
Product Gene Name
anti-CNP antibody
Product Synonym Names
Rabbit Polyclonal (IgG) to Human CNPase; Human CNPase; CNP1; CNPase; Phosphodiesterase CNP
Clonality
Polyclonal
Isotype
IgG
Host
Rabbit
Species Reactivity
Mouse, Rat, Human
Form/Format
PBS, pH 7.3, 0.02% sodium azide, 50% glycerol.
Purity/Purification
Affinity purified
Concentration
1 mg/ml (lot specific)
Specificity
Human CNP / CNPase
Preparation and Storage
Long term: -80 degree C
Short term: -20 degree C
Avoid freeze-thaw cycles.
Molecular Weight
45,099 Da
OMIM
123830
3D Structure
ModBase 3D Structure for P09543
Immunogen
CNPase antibody was raised against recombinant human CNP.
Immunogen Description
Recombinant human CNP.
Immunogen Type
Recombinant protein
Target Species
Human
Applications Tested/Suitable for anti-CNP antibody
Immunohistochemistry (IHC) Paraffin, Western Blot (WB)
Application Notes for anti-CNP antibody
IHC-P (5 ug/ml)
WB (1:500 - 1:2000)

Immunohistochemistry - Paraffin (IHC) of anti-CNP antibody

Human Brain, Cortex: Formalin-Fixed, Paraffin-Embedded (FFPE)
Rabbit Anti-CNP Polyclonal Antibody – Cat# MBS2400358

Immunohistochemistry - Paraffin (IHC) of anti-CNP antibody

Human Brain, Cerebellum: Formalin-Fixed, Paraffin-Embedded (FFPE)
Rabbit Anti-CNP Polyclonal Antibody, Immunohistochemistry - Paraffin (IHC) – Cat# MBS2400358

Western Blot (WB) of anti-CNP antibody

Western blot analysis of extracts of various cell lines, using CNP antibody.
Rabbit Anti-CNP Polyclonal Antibody, Western Blot (WB) – Cat# MBS2400358

Other Notes

Small volumes of anti-CNP antibody vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.

Searchable Terms for CNP purchase

MBS2400358 is an antibody targeting CNP. Also known as Anti-CNPase Antibody IHC-plus. Reactive in Mouse, Rat, Human. Host: Rabbit.

Additional Details

NCBI/Uniprot data below describe general gene information for CNP. It may not necessarily be applicable to this product.

NCBI GI #
94721261
NCBI GeneID
1267
NCBI Accession #
NP_149124.3
UniProt Primary Accession #
P09543
UniProt Related Accession #
P09543
GenBank Nucleotide #
NM_033133.4
NCBI Official Full Name
2',3'-cyclic-nucleotide 3'-phosphodiesterase
NCBI Official Synonym Full Names
2',3'-cyclic nucleotide 3' phosphodiesterase
NCBI Official Symbol
CNP
NCBI Official Synonym Symbols
CNP1
UniProt Protein Name
2',3'-cyclic-nucleotide 3'-phosphodiesterase
Protein Family
2',3'-cyclic-nucleotide 3'-phosphodiesterase
UniProt Gene Name
CNP
UniProt Synonym Gene Names
CNP; CNPase
UniProt Entry Name
CN37_HUMAN
NCBI Protein Information
2',3'-cyclic-nucleotide 3'-phosphodiesterase

UniProt Comments for CNP

CNP: May participate in RNA metabolism in the myelinating cell, CNP is the third most abundant protein in central nervous system myelin. Exists as monomers and homodimers. Belongs to the cyclic nucleotide phosphodiesterase family. 2 isoforms of the human protein are produced by alternative splicing.

Protein type: Phosphodiesterase; Cell development/differentiation; EC 3.1.4.37

Chromosomal Location of Human Ortholog: 17q21

Cellular Component: cytoplasm; extracellular space; melanosome; membrane; microtubule; microvillus; mitochondrial inner membrane; mitochondrial outer membrane; nucleoplasm; nucleus; perinuclear region of cytoplasm; plasma membrane; pseudopodium

Molecular Function: 2',3'-cyclic-nucleotide 3'-phosphodiesterase activity; cyclic nucleotide binding; RNA binding

Biological Process: adult locomotory behavior; aging; axonogenesis; cyclic nucleotide catabolic process; forebrain development; microtubule cytoskeleton organization and biogenesis; oligodendrocyte differentiation; regulation of mitochondrial membrane permeability; response to lipopolysaccharide; response to toxin; substantia nigra development; synaptic transmission
Show more

Research Articles on CNP

1. This study showed that the expression of CNPase protein was significantly decreased but increase expression mrna in ventral prefrontal white matter in major depressive disorder.

Precautions

All of MyBioSource's Products are for scientific laboratory research purposes and are not for diagnostic, therapeutics, prophylactic or in vivo use. Through your purchase, you expressly represent and warrant to MyBioSource that you will properly test and use any Products purchased from MyBioSource in accordance with industry standards. MyBioSource and its authorized distributors reserve the right to refuse to process any order where we reasonably believe that the intended use will fall outside of our acceptable guidelines.

Disclaimer

While every efforts were made to ensure the accuracy of the information provided in this datasheet, MyBioSource will not be liable for any omissions or errors contained herein. MyBioSource reserves the right to make changes to this datasheet at any time without prior notice.

It is the responsibility of the customer to report product performance issues to MyBioSource within 30 days of receipt of the product. Please visit our Terms & Conditions page for more information.

Product Note

Select online data sheet information is drawn from bioinformatics databases, occasionally resulting in ambiguous or non-relevant product information. It is the responsibility of the customer to review, verify, and evaluate the information to make sure it matches their requirements before purchasing the kit. Our ELISA Kit assays are dynamic research tools and sometimes they may be updated and improved. If the format of this assay is important to you then please request the current manual or contact our technical support team with a presales inquiry before placing an order. We will confirm the current details of the assay. We cannot guarantee the sample manual posted online is the most current manual, it is intended to serve as an example only. Please refer to the instructions For Use provided with the assay kit for precise details.

Product PubMed Publications

Products associated with anti-CNP antibody

 Reference Product  PubMed Publications
 MBP antibody  >138 publications with CNP and MBP
 MAG antibody  >56 publications with CNP and MAG
 NPPC antibody  >28 publications with CNP and NPPC
 OLIG2 antibody  >24 publications with CNP and OLIG2
 PLP1 antibody  >16 publications with CNP and PLP1
 STAT5B antibody  >1 publications with CNP and STAT5B

Pathways associated with anti-CNP antibody

 Products by Pathway  Pathway Diagram
 Glial Cell Differentiation Pathway antibodies  Glial Cell Differentiation Pathway Diagram

Diseases associated with anti-CNP antibody

 Disease Name  Pubmed Publications
 Nervous System Diseases Antibodies  >272 publications with CNP and Nervous System Diseases
 Brain Diseases Antibodies  >196 publications with CNP and Brain Diseases
 Hypertension Antibodies  >121 publications with CNP and Hypertension
 Disease Models, Animal Antibodies  >106 publications with CNP and Disease Models, Animal
 Inflammation Antibodies  >79 publications with CNP and Inflammation
 Immune System Diseases Antibodies  >68 publications with CNP and Immune System Diseases
 Kidney Diseases Antibodies  >56 publications with CNP and Kidney Diseases
 Lung Diseases Antibodies  >54 publications with CNP and Lung Diseases
 Hypertrophy Antibodies  >43 publications with CNP and Hypertrophy
 Fibrosis Antibodies  >43 publications with CNP and Fibrosis

Organs/Tissues associated with anti-CNP antibody

 Organ/Tissue Name  Pubmed Publications
 Brain Antibodies  >915 publications with CNP and Brain
 Blood Antibodies  >554 publications with CNP and Blood
 Nerve Antibodies  >491 publications with CNP and Nerve
 Vascular Antibodies  >364 publications with CNP and Vascular
 Heart Antibodies  >341 publications with CNP and Heart
 Muscle Antibodies  >319 publications with CNP and Muscle
 Kidney Antibodies  >189 publications with CNP and Kidney
 Bone Antibodies  >131 publications with CNP and Bone
 Spinal Cord Antibodies  >122 publications with CNP and Spinal Cord
 Lung Antibodies  >96 publications with CNP and Lung
Request a Quote

Please fill out the form below and our representative will get back to you shortly.

MBS000000
Contact Us

Please fill out the form below and our representative will get back to you shortly.

MBS000000