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PPP1R3C Antibody – Rabbit Polyclonal

For Research Use Only. Not for use in diagnostic procedures. Catalog #: MBS3215788

This is a rabbit polyclonal antibody against PPP1R3C. It was validated on Western BlotTarget Description: Protein phosphatase-1 participates in the regulation of a wide variety of cellular functions by reversible protein phosphorylation. The ability of PP1 to… More details

$490 / 0.1 mL +1 FREE 8GB USB
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Sample Manual Insert View PDF
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Testing Data View PDF
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Material Safety Data Sheet View PDF
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Technical Datasheet View PDF
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Product Overview

Online Datasheet in PDF
Product Name
PPP1R3C, Polyclonal Antibody
Full Product Name
PPP1R3C antibody - N-terminal region
Product Gene Name
Product Synonym Gene Name
PPP1R5
Immunogen Sequence
Synthetic peptide located within the following region: PPVKSFLGPY DEFQRRHFVN KLKPLKSCLN IKHKAKSQND WKCSHNQAKK
Clonality
Polyclonal
Host
Rabbit
Species Reactivity
Dog, Horse, Human, Pig, Rabbit
Form/Format
Liquid. Purified antibody supplied in 1x PBS buffer with 0.09% (w/v) sodium azide and 2% sucrose.
Purity/Purification
Affinity Purified
Preparation and Storage
For short term use, store at 2-8 degree C up to 1 week. For long term storage, store at -20 degree C in small aliquots to prevent freeze-thaw cycles.
Antibody/Peptide Pairs
PPP1R3C peptide (MBS3240691) is used for blocking the activity of PPP1R3C antibody (MBS3215788)
Molecular Weight
35kDa
OMIM
602999
3D Structure
ModBase 3D Structure for Q9UQK1
Homology
Dog: 79%; Horse: 79%; Human: 100%; Pig: 79%; Rabbit: 79%
Applications Tested/Suitable for anti-PPP1R3C antibody
Western Blot (WB)

Western Blot (WB) of anti-PPP1R3C antibody

Host: Rabbit
Target Name: PPP1R3C
Sample Type: Human Adult Placenta
Antibody Dilution: 1.0ug/ml
Rabbit Anti-PPP1R3C Polyclonal Antibody – Cat# MBS3215788

Western Blot (WB) of anti-PPP1R3C antibody

Host: Rabbit
Target Name: PPP1R3C
Sample Type: Human Fetal Lung
Antibody Dilution: 1.0ug/ml
Rabbit Anti-PPP1R3C Polyclonal Antibody, Western Blot (WB) – Cat# MBS3215788

Western Blot (WB) of anti-PPP1R3C antibody

Lanes:
1:1ug insoluble STUB1 protein, 2:1ug soluble STUB1 protein, 3:1ug EPM2A protein, 4:1ug insoluble PPP1R3C protein, 5:1ug soluble PPP1R3C protein
Primary Antibody Dilution:
1:1000
Secondary Antibody:
Anti-rabbit-AP
Secondary Antibody Dilution:
1:20,000
Gene Name:
PPP1R3C
Submitted by:
Pedro Castanheira, Biocant
Rabbit Anti-PPP1R3C Polyclonal Antibody, Western Blot (WB) – Cat# MBS3215788

Western Blot (WB) of anti-PPP1R3C antibody

WB Suggested Anti-PPP1R3C Antibody
Titration: 1.0 ug/ml
Positive Control: 293T Whole Cell
Rabbit Anti-PPP1R3C Polyclonal Antibody, Western Blot (WB) – Cat# MBS3215788

Other Notes

Small volumes of anti-PPP1R3C antibody vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.

Searchable Terms for PPP1R3C purchase

MBS3215788 is an antibody targeting PPP1R3C. Also known as PPP1R3C antibody - N-terminal region. Reactive in Dog, Horse, Human, Pig, Rabbit. Host: Rabbit.

Additional Details

NCBI/Uniprot data below describe general gene information for PPP1R3C. It may not necessarily be applicable to this product.

NCBI GI #
NCBI GeneID
NCBI Accession #
UniProt Primary Accession #
UniProt Related Accession #
GenBank Nucleotide #
NCBI Official Full Name
protein phosphatase 1 regulatory subunit 3C
NCBI Official Synonym Full Names
protein phosphatase 1 regulatory subunit 3C
NCBI Official Symbol
PPP1R3C
NCBI Official Synonym Symbols
PTG; PPP1R5
UniProt Protein Name
Protein phosphatase 1 regulatory subunit 3C
UniProt Synonym Protein Names
Protein phosphatase 1 regulatory subunit 5; PP1 subunit R5; Protein targeting to glycogen
UniProt Gene Name
PPP1R3C
UniProt Synonym Gene Names
PPP1R5; PP1 subunit R5; PTG
UniProt Entry Name
PPR3C_HUMAN
NCBI Protein Information
protein phosphatase 1 regulatory subunit 3C

NCBI Summary for PPP1R3C

This gene encodes a carbohydrate binding protein that is a subunit of the protein phosphatase 1 (PP1) complex. PP1 catalyzes reversible protein phosphorylation, which is important in a wide range of cellular activities. The encoded protein affects glycogen biosynthesis by activating glycogen synthase and limiting glycogen breakdown by reducing glycogen phosphorylase activity. DNA hypermethylation of this gene has been found in colorectal cancer patients. The encoded protein also interacts with the laforin protein, which is a protein tyrosine phosphatase implicated in Lafora disease. [provided by RefSeq, Sep 2016]
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UniProt Comments for PPP1R3C

PPP1R3C: Acts as a glycogen-targeting subunit for PP1 and regulates its activity. Activates glycogen synthase, reduces glycogen phosphorylase activity and limits glycogen breakdown. Dramatically increases basal and insulin-stimulated glycogen synthesis upon overexpression in a variety of cell types.

Protein type: Protein phosphatase, regulatory subunit; Motility/polarity/chemotaxis

Chromosomal Location of Human Ortholog: 10q23-q24

Cellular Component: cytosol

Molecular Function: protein binding; protein serine/threonine phosphatase activity; protein phosphatase binding

Biological Process: glycogen biosynthetic process; dephosphorylation; carbohydrate metabolic process; glucose metabolic process; pathogenesis
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Precautions

All of MyBioSource's Products are for scientific laboratory research purposes and are not for diagnostic, therapeutics, prophylactic or in vivo use. Through your purchase, you expressly represent and warrant to MyBioSource that you will properly test and use any Products purchased from MyBioSource in accordance with industry standards. MyBioSource and its authorized distributors reserve the right to refuse to process any order where we reasonably believe that the intended use will fall outside of our acceptable guidelines.

Disclaimer

While every efforts were made to ensure the accuracy of the information provided in this datasheet, MyBioSource will not be liable for any omissions or errors contained herein. MyBioSource reserves the right to make changes to this datasheet at any time without prior notice.

It is the responsibility of the customer to report product performance issues to MyBioSource within 30 days of receipt of the product. Please visit our Terms & Conditions page for more information.

Product Note

Select online data sheet information is drawn from bioinformatics databases, occasionally resulting in ambiguous or non-relevant product information. It is the responsibility of the customer to review, verify, and evaluate the information to make sure it matches their requirements before purchasing the kit. Our ELISA Kit assays are dynamic research tools and sometimes they may be updated and improved. If the format of this assay is important to you then please request the current manual or contact our technical support team with a presales inquiry before placing an order. We will confirm the current details of the assay. We cannot guarantee the sample manual posted online is the most current manual, it is intended to serve as an example only. Please refer to the instructions For Use provided with the assay kit for precise details.

Product PubMed Publications

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