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ADMR Antibody – Rabbit Polyclonal

For Research Use Only. Not for use in diagnostic procedures. Catalog #: MBS418042

ADMR is the receptor for adrenomedullin. The activity of this receptor is mediated by G proteins which activate adenylate cyclase. It is highly expressed in heart, skeletal muscle, immune system, adrenal gland and liver and belongs to the G-protein coupled… More details

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Product Overview

Product Name
ADMR (adrenomedullin receptor), Polyclonal Antibody
Full Product Name
Anti-ADMR (adrenomedullin receptor) Antibody
Product Gene Name
Clonality
Polyclonal
Isotype
IgG
Host
Rabbit
Species Reactivity
Human
Form/Format
Liquid
Purity/Purification
Purified by antigen-specific affinity chromatography.
Concentration
1ug/ul (lot specific)
Preparation and Storage
This product is stable for several weeks at 4 degree C as an undiluted liquid. Dilute only prior to immediate use. For extended storage, aliquot contents and freeze at -20 degree C or below. Avoid cycles of freezing and thawing. Expiration date is one (1) year from date of receipt.
Molecular Weight
45,323 Da
OMIM
Y13583 mRNA
Immunogen
Polyclonal antibody produced in rabbits immunizing with a synthetic peptide corresponding to N-terminal residues of human ADMR (adrenomedullin receptor).
Storage Buffer
PBS, pH 7.4 with 0.05% sodium azide.
Applications Tested/Suitable for anti-ADMR antibody
Western Blot (WB), ELISA (EIA)

Product References and Citations for anti-ADMR antibody

Hanze, J., et al, Biochem. Biophys. Res. Commun. 240 (1), 183-188 (1997) Bomberger, J.M., et al, J. Biol. Chem. 280 (25), 23926-23935 (2005) Albertin, G., et al, Int. J. Mol. Med. 11 (5), 635-639 (2003) Chosa, E., et al, Biochem. Biophys. Res. Commun. 303 (1), 379-386 (2003) Dumont, C.E., et al, Brain Res. 955 (1-2), 64-71 (2002) Hanze, J., et al, Biochem. Biophys. Res. Commun. 291 (5), 1160-1165 (2002) Forneris, M., et al, Int. J. Mol. Med. 8 (6), 675-679 (2001) Mukoyama, M., et al, Peptides 22 (11), 1925-1931 (2001) Jimenez, N., et al, J. Histochem. Cytochem. 47 (9), 1167-1178 (1999)

Other Notes

Small volumes of anti-ADMR antibody vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.

Searchable Terms for ADMR purchase

MBS418042 is an antibody targeting ADMR. Also known as Anti-ADMR (adrenomedullin receptor) Antibody. Reactive in Human. Host: Rabbit.

Additional Details

NCBI/Uniprot data below describe general gene information for ADMR. It may not necessarily be applicable to this product.

NCBI GI #
NCBI GeneID
NCBI Accession #
UniProt Related Accession #
NCBI Official Full Name
adrenomedullin receptor
NCBI Official Synonym Full Names
G protein-coupled receptor 182
NCBI Official Symbol
GPR182
NCBI Official Synonym Symbols
AMR; 7TMR; ADMR; AM-R; G10D; gamrh; hrhAMR
UniProt Protein Name
G-protein coupled receptor 182
UniProt Gene Name
GPR182
UniProt Synonym Gene Names
ADMR
NCBI Protein Information
G-protein coupled receptor 182

NCBI Summary for ADMR

Adrenomedullin is a potent vasodilator peptide that exerts major effects on cardiovascular function. This gene encodes a seven-transmembrane protein that belongs to the family 1 of G-protein coupled receptors. Studies of the rat counterpart suggest that the encoded protein may function as a receptor for adrenomedullin. [provided by RefSeq, Jul 2008]
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UniProt Comments for ADMR

GPR182: Orphan receptor. Belongs to the G-protein coupled receptor 1 family.

Protein type: GPCR, family 1; Membrane protein, integral; Membrane protein, multi-pass; Receptor, GPCR

Chromosomal Location of Human Ortholog: 12q13.3

Molecular Function: G-protein coupled receptor activity; transmembrane receptor activity

Biological Process: cell surface receptor linked signal transduction
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Precautions

All of MyBioSource's Products are for scientific laboratory research purposes and are not for diagnostic, therapeutics, prophylactic or in vivo use. Through your purchase, you expressly represent and warrant to MyBioSource that you will properly test and use any Products purchased from MyBioSource in accordance with industry standards. MyBioSource and its authorized distributors reserve the right to refuse to process any order where we reasonably believe that the intended use will fall outside of our acceptable guidelines.

Disclaimer

While every efforts were made to ensure the accuracy of the information provided in this datasheet, MyBioSource will not be liable for any omissions or errors contained herein. MyBioSource reserves the right to make changes to this datasheet at any time without prior notice.

It is the responsibility of the customer to report product performance issues to MyBioSource within 30 days of receipt of the product. Please visit our Terms & Conditions page for more information.

Product Note

Select online data sheet information is drawn from bioinformatics databases, occasionally resulting in ambiguous or non-relevant product information. It is the responsibility of the customer to review, verify, and evaluate the information to make sure it matches their requirements before purchasing the kit. Our ELISA Kit assays are dynamic research tools and sometimes they may be updated and improved. If the format of this assay is important to you then please request the current manual or contact our technical support team with a presales inquiry before placing an order. We will confirm the current details of the assay. We cannot guarantee the sample manual posted online is the most current manual, it is intended to serve as an example only. Please refer to the instructions For Use provided with the assay kit for precise details.

Product PubMed Publications

Pathways associated with anti-ADMR antibody

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