Rabbit Anti-AGGF1 Polyclonal Antibody – Cat# MBS418043

AGGF1 Antibody – Rabbit Polyclonal

Name: AGGF1 Antibody; Polyclonal; Rabbit; Human-Reactive; MyBioSource
Brand: MyBioSource
SKU: MBS418043
Price: 685 USD
Availability: InStock
Rating: 5 (10 reviews)

For Research Use Only. Not for use in diagnostic procedures. Catalog #: MBS418043

AGGF1 (Angiogenic factor with G patch and FHA domains 1)promotes angiogenesis and the proliferation of endothelial cells. It is able to bind to endothelial cells and promote cell proliferation, suggesting that it may act in an autocrine fashion. AGGF1… More details

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Product Documentation

Sample Manual Insert View PDF

Testing Data View PDF

Certificate of Analysis (COA) View PDF

QC Report View PDF

Material Safety Data Sheet View PDF

Technical Datasheet View PDF

Protocol View PDF

Product Overview

Product Name

AGGF1 (Angiogenic factor with G patch and FHA domains 1), Polyclonal Antibody

Full Product Name

Anti-AGGF1 (Angiogenic factor with G patch and FHA domains 1) Antibody

Product Gene Name

anti-AGGF1 antibody

Clonality

Polyclonal

Isotype

IgG

Host

Rabbit

Species Reactivity

Human

Form/Format

Liquid

Purity/Purification

Purified by antigen-specific affinity chromatography.

Concentration

1ug/ul (lot specific)

Preparation and Storage

This product is stable for several weeks at 4 degree C as an undiluted liquid. Dilute only prior to immediate use. For extended storage, aliquot contents and freeze at -20 degree C or below. Avoid cycles of freezing and thawing. Expiration date is one (1) year from date of receipt.

Molecular Weight

20,506 Da

OMIM

AY500994 mRNA

3D Structure

ModBase 3D Structure for Q8N302

Immunogen

Polyclonal antibody produced in rabbits immunizing with a synthetic peptide corresponding to C-terminal residues of human AGGF1 (Angiogenic factor with G patch and FHA domains 1)

Storage Buffer

PBS, pH 7.4 with 0.05% sodium azide.

Applications Tested/Suitable for anti-AGGF1 antibody

Western Blot (WB), ELISA (EIA)

Product References and Citations for anti-AGGF1 antibody

Tian, X.L., et al, Nature 427 (6975), 640-645 (2004) McKee, A.E., et al, (er) BMC Dev. Biol. 5, 14 (2005) Sousa-Nunes, R., et al, Genome Res. 13 (12), 2609-2620 (2003)

Other Notes

Small volumes of anti-AGGF1 antibody vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.

Searchable Terms for AGGF1 purchase

MBS418043 is an antibody targeting AGGF1. Also known as Anti-AGGF1 (Angiogenic factor with G patch and FHA domains 1) Antibody. Reactive in Human. Host: Rabbit.

Additional Details

NCBI/Uniprot data below describe general gene information for AGGF1. It may not necessarily be applicable to this product.

NCBI GI #

39725952

NCBI GeneID

55109

NCBI Accession #

NP_060516.2

UniProt Primary Accession #

Q8N302

UniProt Secondary Accession #

O00581; Q53YS3; Q9BU84; Q9NW66

UniProt Related Accession #

Q8N302

GenBank Nucleotide #

NM_018046.4

NCBI Official Full Name

angiogenic factor with G patch and FHA domains 1

NCBI Official Synonym Full Names

angiogenic factor with G-patch and FHA domains 1

NCBI Official Symbol

AGGF1

NCBI Official Synonym Symbols

VG5Q; GPATC7; GPATCH7; HSU84971; HUS84971

UniProt Protein Name

Angiogenic factor with G patch and FHA domains 1

UniProt Synonym Protein Names

Angiogenic factor VG5Q; hVG5Q; G patch domain-containing protein 7; Vasculogenesis gene on 5q protein

Protein Family

Angiogenic factor with G patch and FHA domains

UniProt Gene Name

AGGF1

UniProt Synonym Gene Names

GPATC7; GPATCH7; VG5Q; hVG5Q

NCBI Protein Information

angiogenic factor with G patch and FHA domains 1

NCBI Summary for AGGF1

This gene encodes an angiogenic factor that promotes proliferation of endothelial cells. Mutations in this gene are associated with a susceptibility to Klippel-Trenaunay syndrome. Pseudogenes of this gene are found on chromosomes 3, 4, 10 and 16.[provided by RefSeq, Sep 2010]

UniProt Comments for AGGF1

AGGF1: Promotes angiogenesis and the proliferation of endothelial cells. Able to bind to endothelial cells and promote cell proliferation, suggesting that it may act in an autocrine fashion. Defects in AGGF1 are a cause of Klippel-Trenaunay syndrome (KTS). KTS is a congenital disease characterized by malformations of capillary (98% of KTS patients), venous (72%) and lymphatic (11%) vessels, and bony and soft tissue hypertrophy that leads to large cutaneous hemangiomata with hypertrophy of the related bones and soft tissues. 3 isoforms of the human protein are produced by alternative splicing.

Protein type: Cell adhesion; RNA processing

Chromosomal Location of Human Ortholog: 5q13.3

Cellular Component: cytoplasm; extracellular region; nuclear speck; perinuclear region of cytoplasm

Molecular Function: protein binding; RNA binding

Biological Process: cell adhesion; mRNA processing; positive regulation of angiogenesis; positive regulation of endothelial cell proliferation; regulation of RNA splicing; RNA processing; vasculogenesis

Disease: Klippel-trenaunay-weber Syndrome

Research Articles on AGGF1

1. Overexpression of AGGF1 is correlated with angiogenesis in hepatocellular carcinoma.

Precautions

All of MyBioSource's Products are for scientific laboratory research purposes and are not for diagnostic, therapeutics, prophylactic or in vivo use. Through your purchase, you expressly represent and warrant to MyBioSource that you will properly test and use any Products purchased from MyBioSource in accordance with industry standards. MyBioSource and its authorized distributors reserve the right to refuse to process any order where we reasonably believe that the intended use will fall outside of our acceptable guidelines.

Disclaimer

While every efforts were made to ensure the accuracy of the information provided in this datasheet, MyBioSource will not be liable for any omissions or errors contained herein. MyBioSource reserves the right to make changes to this datasheet at any time without prior notice.

It is the responsibility of the customer to report product performance issues to MyBioSource within 30 days of receipt of the product. Please visit our Terms & Conditions page for more information.

Product Note

Select online data sheet information is drawn from bioinformatics databases, occasionally resulting in ambiguous or non-relevant product information. It is the responsibility of the customer to review, verify, and evaluate the information to make sure it matches their requirements before purchasing the kit. Our ELISA Kit assays are dynamic research tools and sometimes they may be updated and improved. If the format of this assay is important to you then please request the current manual or contact our technical support team with a presales inquiry before placing an order. We will confirm the current details of the assay. We cannot guarantee the sample manual posted online is the most current manual, it is intended to serve as an example only. Please refer to the instructions For Use provided with the assay kit for precise details.

Product PubMed Publications

Products associated with anti-AGGF1 antibody

Reference Product	PubMed Publications
TNFSF12 antibody	>2 publications with AGGF1 and TNFSF12

Diseases associated with anti-AGGF1 antibody

Disease Name	Pubmed Publications
Klippel-Trenaunay-Weber Syndrome Antibodies	>11 publications with AGGF1 and Klippel-Trenaunay-Weber Syndrome
Necrosis Antibodies	>5 publications with AGGF1 and Necrosis
Inflammation Antibodies	>3 publications with AGGF1 and Inflammation
Hypertrophy Antibodies	>2 publications with AGGF1 and Hypertrophy
Arteriosclerosis Antibodies	>1 publications with AGGF1 and Arteriosclerosis
Skin Neoplasms Antibodies	>1 publications with AGGF1 and Skin Neoplasms
Myocardial Infarction Antibodies	>1 publications with AGGF1 and Myocardial Infarction
Lymphoma Antibodies	>1 publications with AGGF1 and Lymphoma
Urinary Bladder Neoplasms Antibodies	>1 publications with AGGF1 and Urinary Bladder Neoplasms
Brain Diseases Antibodies	>1 publications with AGGF1 and Brain Diseases

Organs/Tissues associated with anti-AGGF1 antibody

Organ/Tissue Name	Pubmed Publications
Vascular Antibodies	>14 publications with AGGF1 and Vascular
Blood Antibodies	>7 publications with AGGF1 and Blood
Heart Antibodies	>2 publications with AGGF1 and Heart
Lung Antibodies	>2 publications with AGGF1 and Lung
Muscle Antibodies	>1 publications with AGGF1 and Muscle
Skin Antibodies	>1 publications with AGGF1 and Skin
Uterus Antibodies	>1 publications with AGGF1 and Uterus
Bone Antibodies	>1 publications with AGGF1 and Bone
Bladder Antibodies	>1 publications with AGGF1 and Bladder
Embryonic Tissue Antibodies	>1 publications with AGGF1 and Embryonic Tissue