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CDCA5 Antibody – Rabbit Polyclonal

For Research Use Only. Not for use in diagnostic procedures. Catalog #: MBS418075

CDCA5 (Cell division cycle associated 5) is a regulator of sister chromatid cohesion in mitosis. CDCA5 may act by regulating the ability of the cohesin complex to mediate sister chromatid cohesion, perhaps by altering the nature of the interaction of cohesin… More details

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Product Documentation
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Sample Manual Insert View PDF
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Testing Data View PDF
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Certificate of Analysis (COA) View PDF
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Material Safety Data Sheet View PDF
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Technical Datasheet View PDF
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Product Overview

Product Name
CDCA5 (Cell division cycle associated 5), Polyclonal Antibody
Full Product Name
Anti-CDCA5 (Cell division cycle associated 5) Antibody
Product Gene Name
anti-CDCA5 antibody
Clonality
Polyclonal
Isotype
IgG
Host
Rabbit
Species Reactivity
Human
Form/Format
Liquid
Purity/Purification
Purified by antigen-specific affinity chromatography.
Concentration
1ug/ul (lot specific)
Preparation and Storage
This product is stable for several weeks at 4 degree C as an undiluted liquid. Dilute only prior to immediate use. For extended storage, aliquot contents and freeze at -20 degree C or below. Avoid cycles of freezing and thawing. Expiration date is one (1) year from date of receipt.
Molecular Weight
27,601 Da
OMIM
BG354578 mRNA
Immunogen
Polyclonal antibody produced in rabbits immunizing with a synthetic peptide corresponding to N-terminal residues of human CDCA5 (Cell division cycle associated 5)
Storage Buffer
PBS, pH 7.4 with 0.05% sodium azide.
Applications Tested/Suitable for anti-CDCA5 antibody
Western Blot (WB), ELISA (EIA)

Product References and Citations for anti-CDCA5 antibody

Walker, M.G., Curr Cancer Drug Targets 1 (1), 73-83 (2001) Rankin, S., et al, Mol. Cell 18 (2), 185-200 (2005) Rankin, S., et al, Mol. Cell 18, 609-609 (2005)

Other Notes

Small volumes of anti-CDCA5 antibody vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.

Searchable Terms for CDCA5 purchase

MBS418075 is an antibody targeting CDCA5. Also known as Anti-CDCA5 (Cell division cycle associated 5) Antibody. Reactive in Human. Host: Rabbit.

Additional Details

NCBI/Uniprot data below describe general gene information for CDCA5. It may not necessarily be applicable to this product.

NCBI GI #
15012190
NCBI GeneID
113130
NCBI Accession #
AAH11000.1
UniProt Secondary Accession #
A8K625
UniProt Related Accession #
Q96FF9
NCBI Official Full Name
Cell division cycle associated 5
NCBI Official Synonym Full Names
cell division cycle associated 5
NCBI Official Symbol
CDCA5
NCBI Official Synonym Symbols
SORORIN
UniProt Protein Name
Sororin
UniProt Synonym Protein Names
Cell division cycle-associated protein 5; p35
Protein Family
Sororin
UniProt Gene Name
CDCA5
NCBI Protein Information
sororin

UniProt Comments for CDCA5

CDCA5: Regulator of sister chromatid cohesion in mitosis stabilizing cohesin complex association with chromatin. May antagonize the action of WAPAL which stimulates cohesin dissociation from chromatin. Cohesion ensures that chromosome partitioning is accurate in both meiotic and mitotic cells and plays an important role in DNA repair. Required for efficient DNA double-stranded break repair. Belongs to the sororin family.

Protein type: Cell cycle regulation

Chromosomal Location of Human Ortholog: 11q13.1

Cellular Component: chromosome; chromosome, pericentric region; cohesin complex; cytoplasm; cytosol; nuclear chromatin; nucleoplasm; nucleus; plasma membrane

Molecular Function: chromatin binding; protein binding

Biological Process: double-strand break repair; G1/S transition of mitotic cell cycle; mitosis; mitotic chromosome condensation; mitotic metaphase plate congression; mitotic sister chromatid cohesion; positive regulation of exit from mitosis; sister chromatid cohesion
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Research Articles on CDCA5

1. The results suggest that CDCA5 functions as a critical gene supporting oral squamous cell carcinoma progression and that targeting CDCA5 may be a useful therapeutic strategy for oral squamous cell carcinoma.

Precautions

All of MyBioSource's Products are for scientific laboratory research purposes and are not for diagnostic, therapeutics, prophylactic or in vivo use. Through your purchase, you expressly represent and warrant to MyBioSource that you will properly test and use any Products purchased from MyBioSource in accordance with industry standards. MyBioSource and its authorized distributors reserve the right to refuse to process any order where we reasonably believe that the intended use will fall outside of our acceptable guidelines.

Disclaimer

While every efforts were made to ensure the accuracy of the information provided in this datasheet, MyBioSource will not be liable for any omissions or errors contained herein. MyBioSource reserves the right to make changes to this datasheet at any time without prior notice.

It is the responsibility of the customer to report product performance issues to MyBioSource within 30 days of receipt of the product. Please visit our Terms & Conditions page for more information.

Product Note

Select online data sheet information is drawn from bioinformatics databases, occasionally resulting in ambiguous or non-relevant product information. It is the responsibility of the customer to review, verify, and evaluate the information to make sure it matches their requirements before purchasing the kit. Our ELISA Kit assays are dynamic research tools and sometimes they may be updated and improved. If the format of this assay is important to you then please request the current manual or contact our technical support team with a presales inquiry before placing an order. We will confirm the current details of the assay. We cannot guarantee the sample manual posted online is the most current manual, it is intended to serve as an example only. Please refer to the instructions For Use provided with the assay kit for precise details.

Product PubMed Publications

Products associated with anti-CDCA5 antibody

 Reference Product  PubMed Publications
 WAPAL antibody  >6 publications with CDCA5 and WAPAL
 RAD21 antibody  >6 publications with CDCA5 and RAD21
 SMC3 antibody  >6 publications with CDCA5 and SMC3
 SGOL1 antibody  >3 publications with CDCA5 and SGOL1
 PLK1 antibody  >2 publications with CDCA5 and PLK1
 STAG2 antibody  >1 publications with CDCA5 and STAG2
 ESCO1 antibody  >1 publications with CDCA5 and ESCO1
 PDS5A antibody  >1 publications with CDCA5 and PDS5A

Pathways associated with anti-CDCA5 antibody

 Products by Pathway  Pathway Diagram
 Cell Cycle Pathway antibodies  Cell Cycle Pathway Diagram
 Cell Cycle, Mitotic Pathway antibodies  Cell Cycle, Mitotic Pathway Diagram
 Establishment Of Sister Chromatid Cohesion Pathway antibodies  Establishment Of Sister Chromatid Cohesion Pathway Diagram
 M Phase Pathway antibodies  M Phase Pathway Diagram
 MicroRNAs In Cancer Pathway antibodies  MicroRNAs In Cancer Pathway Diagram
 MicroRNAs In Cancer Pathway antibodies  MicroRNAs In Cancer Pathway Diagram
 Mitotic Anaphase Pathway antibodies  Mitotic Anaphase Pathway Diagram
 Mitotic Metaphase And Anaphase Pathway antibodies  Mitotic Metaphase And Anaphase Pathway Diagram
 Mitotic Prometaphase Pathway antibodies  Mitotic Prometaphase Pathway Diagram
 Resolution Of Sister Chromatid Cohesion Pathway antibodies  Resolution Of Sister Chromatid Cohesion Pathway Diagram

Diseases associated with anti-CDCA5 antibody

 Disease Name  Pubmed Publications
 Nervous System Diseases Antibodies  >7 publications with CDCA5 and Nervous System Diseases
 Lung Neoplasms Antibodies  >6 publications with CDCA5 and Lung Neoplasms
 Liver Diseases Antibodies  >3 publications with CDCA5 and Liver Diseases
 Congenital Abnormalities Antibodies  >3 publications with CDCA5 and Congenital Abnormalities
 Cell Transformation, Neoplastic Antibodies  >2 publications with CDCA5 and Cell Transformation, Neoplastic
 Neoplasm Invasiveness Antibodies  >2 publications with CDCA5 and Neoplasm Invasiveness
 Neoplasms, Experimental Antibodies  >1 publications with CDCA5 and Neoplasms, Experimental
 Cardiovascular Diseases Antibodies  >1 publications with CDCA5 and Cardiovascular Diseases
 Breast Neoplasms Antibodies  >1 publications with CDCA5 and Breast Neoplasms
 Disease Models, Animal Antibodies  >1 publications with CDCA5 and Disease Models, Animal

Organs/Tissues associated with anti-CDCA5 antibody

 Organ/Tissue Name  Pubmed Publications
 Nerve Antibodies  >7 publications with CDCA5 and Nerve
 Brain Antibodies  >7 publications with CDCA5 and Brain
 Lung Antibodies  >6 publications with CDCA5 and Lung
 Prostate Antibodies  >6 publications with CDCA5 and Prostate
 Blood Antibodies  >4 publications with CDCA5 and Blood
 Lymph Node Antibodies  >3 publications with CDCA5 and Lymph Node
 Lymph Antibodies  >3 publications with CDCA5 and Lymph
 Pancreas Antibodies  >2 publications with CDCA5 and Pancreas
 Bone Antibodies  >2 publications with CDCA5 and Bone
 Stomach Antibodies  >1 publications with CDCA5 and Stomach
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