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ELP3 Antibody – Rabbit Polyclonal

For Research Use Only. Not for use in diagnostic procedures. Catalog #: MBS418115

Elongator is a component of early elongation complexes formed in cell nuclear extracts and can interact directly with RNA polymerase II. ELP contains four isoforms: ELP1, ELP2, ELP3, and Ad4BP/SF1. ELP1 functioned as a repressor. The ELP2, ELP3, and Ad4BP/SF1… More details

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Product Documentation
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Sample Manual Insert View PDF
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Testing Data View PDF
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Certificate of Analysis (COA) View PDF
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Material Safety Data Sheet View PDF
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Technical Datasheet View PDF
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Product Overview

Product Name
ELP3 (elongation protein 3 homolog), Polyclonal Antibody
Full Product Name
Anti-ELP3 (elongation protein 3 homolog) Antibody
Product Gene Name
Clonality
Polyclonal
Isotype
IgG
Host
Rabbit
Species Reactivity
Human, Mouse
Form/Format
Liquid
Purity/Purification
Purified by antigen-specific affinity chromatography.
Concentration
1ug/ul (lot specific)
Preparation and Storage
This product is stable for several weeks at 4 degree C as an undiluted liquid. Dilute only prior to immediate use. For extended storage, aliquot contents and freeze at -20 degree C or below. Avoid cycles of freezing and thawing. Expiration date is one (1) year from date of receipt.
Molecular Weight
52,202 Da
OMIM
AK001284 mRNA
Immunogen
Polyclonal antibody produced in rabbits immunizing with a synthetic peptide corresponding to C-terminal residues of human ELP3 (elongation protein 3 homolog)
Storage Buffer
PBS, pH 7.4 with 0.05% sodium azide.
Applications Tested/Suitable for anti-ELP3 antibody
Western Blot (WB), ELISA (EIA)

Product References and Citations for anti-ELP3 antibody

Chinenov, Y., Trends Biochem. Sci. 27 (3), 115-117 (2002) Hawkes, N.A., et al, J. Biol. Chem. 277 (4), 3047-3052 (2002) Ninomiya, Y., et al, J. Biochem. 118 (2), 380-389 (1995)

Other Notes

Small volumes of anti-ELP3 antibody vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.

Searchable Terms for ELP3 purchase

MBS418115 is an antibody targeting ELP3. Also known as Anti-ELP3 (elongation protein 3 homolog) Antibody. Reactive in Human, Mouse. Host: Rabbit.

Additional Details

NCBI/Uniprot data below describe general gene information for ELP3. It may not necessarily be applicable to this product.

NCBI GI #
NCBI GeneID
NCBI Accession #
UniProt Secondary Accession #
UniProt Related Accession #
NCBI Official Full Name
elongation protein 3 homolog, partial
NCBI Official Synonym Full Names
elongator acetyltransferase complex subunit 3
NCBI Official Symbol
ELP3
NCBI Official Synonym Symbols
KAT9
UniProt Protein Name
Elongator complex protein 3
UniProt Gene Name
ELP3
UniProt Synonym Gene Names
hELP3
NCBI Protein Information
elongator complex protein 3

NCBI Summary for ELP3

ELP3 is the catalytic subunit of the histone acetyltransferase elongator complex, which contributes to transcript elongation and also regulates the maturation of projection neurons (Creppe et al., 2009 [PubMed 19185337]).[supplied by OMIM, Apr 2009]

UniProt Comments for ELP3

ELP3: a histone acetyltransferase. A subunit of the Elongator complex, which associates with the elongating, hyperphosphorylated form of RNA polymerase II.

Protein type: Acetyltransferase; EC 2.3.1.48

Chromosomal Location of Human Ortholog: 8p21.1

Cellular Component: cytoplasm; Elongator holoenzyme complex; histone acetyltransferase complex; nucleolus; transcription elongation factor complex

Molecular Function: H3 histone acetyltransferase activity; H4 histone acetyltransferase activity; phosphorylase kinase regulator activity; protein binding

Biological Process: central nervous system development; neuron migration; positive regulation of cell migration; regulation of transcription from RNA polymerase II promoter; RNA elongation from RNA polymerase II promoter
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Precautions

All of MyBioSource's Products are for scientific laboratory research purposes and are not for diagnostic, therapeutics, prophylactic or in vivo use. Through your purchase, you expressly represent and warrant to MyBioSource that you will properly test and use any Products purchased from MyBioSource in accordance with industry standards. MyBioSource and its authorized distributors reserve the right to refuse to process any order where we reasonably believe that the intended use will fall outside of our acceptable guidelines.

Disclaimer

While every efforts were made to ensure the accuracy of the information provided in this datasheet, MyBioSource will not be liable for any omissions or errors contained herein. MyBioSource reserves the right to make changes to this datasheet at any time without prior notice.

It is the responsibility of the customer to report product performance issues to MyBioSource within 30 days of receipt of the product. Please visit our Terms & Conditions page for more information.

Product Note

Select online data sheet information is drawn from bioinformatics databases, occasionally resulting in ambiguous or non-relevant product information. It is the responsibility of the customer to review, verify, and evaluate the information to make sure it matches their requirements before purchasing the kit. Our ELISA Kit assays are dynamic research tools and sometimes they may be updated and improved. If the format of this assay is important to you then please request the current manual or contact our technical support team with a presales inquiry before placing an order. We will confirm the current details of the assay. We cannot guarantee the sample manual posted online is the most current manual, it is intended to serve as an example only. Please refer to the instructions For Use provided with the assay kit for precise details.

Product PubMed Publications

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