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ERBB2IP Antibody – Rabbit Polyclonal

For Research Use Only. Not for use in diagnostic procedures. Catalog #: MBS418116

ERBB2IP (Erbb2-interacting protein) acts as an adapter for the receptor ERBB2, in epithelia. By binding the unphosphorylated Tyr-1248 of receptor ERBB2, it may contribute to stabilize this unphosphorylated state. ERBB2IP (Erbb2-interacting protein) interacts… More details

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Sample Manual Insert View PDF
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Testing Data View PDF
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Certificate of Analysis (COA) View PDF
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Material Safety Data Sheet View PDF
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Technical Datasheet View PDF
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Product Overview

Product Name
ERBB2IP (Erbb2-interacting protein), Polyclonal Antibody
Full Product Name
Anti-ERBB2IP (Erbb2-interacting protein) Antibody
Product Gene Name
Clonality
Polyclonal
Isotype
IgG
Host
Rabbit
Species Reactivity
Human, Mouse
Form/Format
Liquid
Purity/Purification
Purified by antigen-specific affinity chromatography.
Concentration
1ug/ul (lot specific)
Preparation and Storage
This product is stable for several weeks at 4 degree C as an undiluted liquid. Dilute only prior to immediate use. For extended storage, aliquot contents and freeze at -20 degree C or below. Avoid cycles of freezing and thawing. Expiration date is one (1) year from date of receipt.
Molecular Weight
153,543 Da
OMIM
AF263744 mRNA
Immunogen
Polyclonal antibody produced in rabbits immunizing with a synthetic peptide corresponding to N-terminal residues of human ERBB2IP (Erbb2-interacting protein)
Storage Buffer
PBS, pH 7.4 with 0.05% sodium azide.
Applications Tested/Suitable for anti-ERBB2IP antibody
Western Blot (WB), ELISA (EIA)

Product References and Citations for anti-ERBB2IP antibody

Borg, J.P., et al, Nat. Cell Biol. 2 (7), 407-414 (2000) Favre, B., et al, J. Biol. Chem. 276 (35), 32427-32436 (2001) Laura, R.P., et al, J. Biol. Chem. 277 (15), 12906-12914 (2002) Beausoleil, S.A., et al, Proc. Natl. Acad. Sci. U.S.A. 101 (33), 12130-12135 (2004) Birrane, G., et al, J. Biol. Chem. 278 (3), 1399-1402 (2003) Skelton, N.J., et al, J. Biol. Chem. 278 (9), 7645-7654 (2003)

Other Notes

Small volumes of anti-ERBB2IP antibody vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.

Searchable Terms for ERBB2IP purchase

MBS418116 is an antibody targeting ERBB2IP. Also known as Anti-ERBB2IP (Erbb2-interacting protein) Antibody. Reactive in Human, Mouse. Host: Rabbit.

Additional Details

NCBI/Uniprot data below describe general gene information for ERBB2IP. It may not necessarily be applicable to this product.

NCBI GI #
NCBI GeneID
NCBI Accession #
UniProt Secondary Accession #
UniProt Related Accession #
NCBI Official Full Name
Erbb2 interacting protein
NCBI Official Synonym Full Names
erbb2 interacting protein
NCBI Official Symbol
ERBIN
NCBI Official Synonym Symbols
LAP2; ERBB2IP; HEL-S-78
UniProt Protein Name
Erbin
UniProt Synonym Protein Names
Densin-180-like protein; Erbb2-interacting protein
UniProt Gene Name
ERBIN
NCBI Protein Information
erbin

NCBI Summary for ERBB2IP

This gene is a member of the leucine-rich repeat and PDZ domain (LAP) family. The encoded protein contains 17 leucine-rich repeats and one PDZ domain. It binds to the unphosphorylated form of the ERBB2 protein and regulates ERBB2 function and localization. It has also been shown to affect the Ras signaling pathway by disrupting Ras-Raf interaction. Alternatively spliced transcript variants encoding multiple isoforms have been observed for this gene. [provided by RefSeq, Nov 2011]
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UniProt Comments for ERBB2IP

Acts as an adapter for the receptor ERBB2, in epithelia. By binding the unphosphorylated 'Tyr-1248' of receptor ERBB2, it may contribute to stabilize this unphosphorylated state (PubMed:16203728). Inhibits NOD2-dependent NF-kappa-B signaling and proinflammatory cytokine secretion (PubMed:16203728).

Precautions

All of MyBioSource's Products are for scientific laboratory research purposes and are not for diagnostic, therapeutics, prophylactic or in vivo use. Through your purchase, you expressly represent and warrant to MyBioSource that you will properly test and use any Products purchased from MyBioSource in accordance with industry standards. MyBioSource and its authorized distributors reserve the right to refuse to process any order where we reasonably believe that the intended use will fall outside of our acceptable guidelines.

Disclaimer

While every efforts were made to ensure the accuracy of the information provided in this datasheet, MyBioSource will not be liable for any omissions or errors contained herein. MyBioSource reserves the right to make changes to this datasheet at any time without prior notice.

It is the responsibility of the customer to report product performance issues to MyBioSource within 30 days of receipt of the product. Please visit our Terms & Conditions page for more information.

Product Note

Select online data sheet information is drawn from bioinformatics databases, occasionally resulting in ambiguous or non-relevant product information. It is the responsibility of the customer to review, verify, and evaluate the information to make sure it matches their requirements before purchasing the kit. Our ELISA Kit assays are dynamic research tools and sometimes they may be updated and improved. If the format of this assay is important to you then please request the current manual or contact our technical support team with a presales inquiry before placing an order. We will confirm the current details of the assay. We cannot guarantee the sample manual posted online is the most current manual, it is intended to serve as an example only. Please refer to the instructions For Use provided with the assay kit for precise details.

Product PubMed Publications

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