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FOLR2 Antibody – Rabbit Polyclonal

For Research Use Only. Not for use in diagnostic procedures. Catalog #: MBS418123

The FOLR2 (Folate receptor beta) binds to folate and reduced folic acid derivatives and mediates delivery of 5-methyltetrahydrofolate to the interior of cells. More details

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Product Documentation
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Sample Manual Insert View PDF
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Testing Data View PDF
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Certificate of Analysis (COA) View PDF
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QC Report View PDF
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Material Safety Data Sheet View PDF
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Technical Datasheet View PDF
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Protocol View PDF

Product Overview

Product Name
FOLR2 (Folate receptor beta), Polyclonal Antibody
Full Product Name
Anti-FOLR2 (Folate receptor beta) Antibody
Product Gene Name
Clonality
Polyclonal
Isotype
IgG
Host
Rabbit
Species Reactivity
Human, Mouse
Form/Format
Liquid
Purity/Purification
Purified by antigen-specific affinity chromatography
Concentration
1ug / ul (lot specific)
Preparation and Storage
This product is stable for several weeks at 4 degree C as an undiluted liquid. Dilute only prior to immediate use. For extended storage, aliquot contents and freeze at -20 degree C or below. Avoid cycles of freezing and thawing. Expiration date is one (1) year from date of receipt.
Molecular Weight
28,821 Da
3D Structure
ModBase 3D Structure for Q05685
Immunogen
Polyclonal antibody produced in rabbits immunizing with a synthetic peptide corresponding to N-terminal residues of human FOLR2 (Folate receptor beta precursor)
Storage Buffer
PBS, pH 7.4 with 0.05% sodium azide.
Applications Tested/Suitable for anti-FOLR2 antibody
Western Blot (WB), ELISA (EIA)

Product References and Citations for anti-FOLR2 antibody

Page, S.T, et al, J. Mol. Biol. 229 (4), 1175-1183 (1993)Ratnam, M., et al, Biochemistry 28 (20), 8249-8254 (1989)Sadasivan, E., et al, J. Biol. Chem. 269 (7), 4725-4735 (1994)Yan, W. and Ratnam, M., Biochemistry 34 (44), 14594-14600 (1995)Wang, J., et al, Biochemistry 36 (47), 14583-14592 (1997)

Other Notes

Small volumes of anti-FOLR2 antibody vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.

Searchable Terms for FOLR2 purchase

MBS418123 is an antibody targeting FOLR2. Also known as Anti-FOLR2 (Folate receptor beta) Antibody. Reactive in Human, Mouse. Host: Rabbit.

Additional Details

NCBI/Uniprot data below describe general gene information for FOLR2. It may not necessarily be applicable to this product.

NCBI GI #
NCBI GeneID
NCBI Accession #
UniProt Primary Accession #
UniProt Related Accession #
GenBank Nucleotide #
NCBI Official Full Name
folate receptor beta
NCBI Official Synonym Full Names
folate receptor 2 (fetal)
NCBI Official Symbol
Folr2
NCBI Official Synonym Symbols
FBP2; FR-P3; Folbp2; FR-beta; Folbp-2
UniProt Protein Name
Folate receptor beta
UniProt Synonym Protein Names
Folate receptor 2; Folate-binding protein 2
Protein Family
UniProt Gene Name
Folr2
UniProt Synonym Gene Names
Fbp2; Folbp2; FR-beta
NCBI Protein Information
folate receptor beta

NCBI Summary for FOLR2

This gene encodes a receptor protein located on the plasma membrane that mediates folate uptake by cells. Mice lacking the product of this gene show no defects in embryonic development and grow normally into fertile adults. However, such mice were found to be highly susceptible to the teratogenic effects of arsenic. Alternate splicing of this gene results in multiple transcript variants. [provided by RefSeq, Dec 2014]
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UniProt Comments for FOLR2

FOLR2: Binds to folate and reduced folic acid derivatives and mediates delivery of 5-methyltetrahydrofolate to the interior of cells. Belongs to the folate receptor family.

Protein type: Membrane protein, GPI anchor

Chromosomal Location of Human Ortholog: 7|7 E2

Cellular Component: anchored to external side of plasma membrane; cell surface

Molecular Function: drug binding; folic acid binding; folic acid transporter activity; methotrexate binding

Biological Process: folic acid transport; positive regulation of cell proliferation; posttranslational protein targeting to membrane
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Precautions

All of MyBioSource's Products are for scientific laboratory research purposes and are not for diagnostic, therapeutics, prophylactic or in vivo use. Through your purchase, you expressly represent and warrant to MyBioSource that you will properly test and use any Products purchased from MyBioSource in accordance with industry standards. MyBioSource and its authorized distributors reserve the right to refuse to process any order where we reasonably believe that the intended use will fall outside of our acceptable guidelines.

Disclaimer

While every efforts were made to ensure the accuracy of the information provided in this datasheet, MyBioSource will not be liable for any omissions or errors contained herein. MyBioSource reserves the right to make changes to this datasheet at any time without prior notice.

It is the responsibility of the customer to report product performance issues to MyBioSource within 30 days of receipt of the product. Please visit our Terms & Conditions page for more information.

Product Note

Select online data sheet information is drawn from bioinformatics databases, occasionally resulting in ambiguous or non-relevant product information. It is the responsibility of the customer to review, verify, and evaluate the information to make sure it matches their requirements before purchasing the kit. Our ELISA Kit assays are dynamic research tools and sometimes they may be updated and improved. If the format of this assay is important to you then please request the current manual or contact our technical support team with a presales inquiry before placing an order. We will confirm the current details of the assay. We cannot guarantee the sample manual posted online is the most current manual, it is intended to serve as an example only. Please refer to the instructions For Use provided with the assay kit for precise details.

Product PubMed Publications

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