Rabbit Anti-RAB13 Polyclonal Antibody – Cat# MBS418217

RAB13 Antibody – Rabbit Polyclonal

Name: RAB13 Antibody; Polyclonal; Rabbit; Human-Reactive; MyBioSource
Brand: MyBioSource
SKU: MBS418217
Price: 685 USD
Availability: InStock
Rating: 5 (10 reviews)

For Research Use Only. Not for use in diagnostic procedures. Catalog #: MBS418217

The RAB13 (Ras-related protein Rab-13, growth-inhibiting gene 4 protein) could participate in polarized transport, in the assembly and/or the activity of tight junctions. Rab13 specifically mediates the continuous endocytic recycling of occludin to the cell… More details

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Product Documentation

Sample Manual Insert View PDF

Testing Data View PDF

Certificate of Analysis (COA) View PDF

QC Report View PDF

Material Safety Data Sheet View PDF

Technical Datasheet View PDF

Protocol View PDF

Product Overview

Product Name

RAB13 (Ras-related protein Rab-13, growth-inhibiting gene 4 protein), Polyclonal Antibody

Full Product Name

Anti-RAB13 (Ras-related protein Rab-13, growth-inhibiting gene 4 protein) Antibody

Product Gene Name

anti-RAB13 antibody

Clonality

Polyclonal

Isotype

IgG

Host

Rabbit

Species Reactivity

Human

Form/Format

Liquid

Purity/Purification

Purified by antigen-specific affinity chromatography.

Concentration

1ug/ul (lot specific)

Preparation and Storage

This product is stable for several weeks at 4 degree C as an undiluted liquid. Dilute only prior to immediate use. For extended storage, aliquot contents and freeze at -20 degree C or below. Avoid cycles of freezing and thawing. Expiration date is one (1) year from date of receipt.

Molecular Weight

22,774 Da

OMIM

X75593 mRNA

3D Structure

ModBase 3D Structure for P51153

Immunogen

Polyclonal antibody produced in rabbits immunizing with a synthetic peptide corresponding to N-terminal residues of human RAB13 (Ras-related protein Rab-13, growth-inhibiting gene 4 protein)

Storage Buffer

PBS, pH 7.4 with 0.05% sodium azide.

Applications Tested/Suitable for anti-RAB13 antibody

Western Blot (WB), ELISA (EIA)

Product References and Citations for anti-RAB13 antibody

Zahraoui, A., et al, J. Cell Biol. 124 (1-2), 101-115 (1994) Morimoto, S., et al, J. Biol. Chem. 280 (3), 2220-2228 (2005) Bao, S., et al, Horm. Metab. Res. 30 (11), 656-662 (1998) Marzesco, A.M., et al, J. Biol. Chem. 273 (35), 22340-22345 (1998) Leek, J.P., et al, Cytogenet. Cell Genet. 79 (3-4), 210-211 (1997) Joberty, G., et al, FEBS Lett. 330 (3), 323-328 (1993)

Other Notes

Small volumes of anti-RAB13 antibody vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.

Searchable Terms for RAB13 purchase

MBS418217 is an antibody targeting RAB13. Also known as Anti-RAB13 (Ras-related protein Rab-13, growth-inhibiting gene 4 protein) Antibody. Reactive in Human. Host: Rabbit.

Additional Details

NCBI/Uniprot data below describe general gene information for RAB13. It may not necessarily be applicable to this product.

NCBI GI #

4506363

NCBI GeneID

5872

NCBI Accession #

NP_002861.1

UniProt Primary Accession #

P51153

UniProt Secondary Accession #

Q5U0A6; Q6GPG6; Q96GU4; A8K6B5; D3DV67

UniProt Related Accession #

P51153

GenBank Nucleotide #

NM_002870.3

NCBI Official Full Name

ras-related protein Rab-13 isoform 1

NCBI Official Synonym Full Names

RAB13, member RAS oncogene family

NCBI Official Symbol

RAB13

NCBI Official Synonym Symbols

GIG4

UniProt Protein Name

Ras-related protein Rab-13

UniProt Synonym Protein Names

Cell growth-inhibiting gene 4 protein

Protein Family

Ras-related protein

UniProt Gene Name

RAB13

NCBI Protein Information

ras-related protein Rab-13

NCBI Summary for RAB13

This gene is a member of the Rab family of small G proteins and plays a role in regulating membrane trafficking between trans-Golgi network (TGN) and recycling endosomes (RE). The encoded protein is involved in the assembly of tight junctions, which are components of the apical junctional complex (AJC) of epithelial cells. The AJC plays a role in forming a barrier between luminal contents and the underlying tissue. Additional functions associated with the protein include endocytic recycling of occludin, regulation of epithelial cell scattering, neuronal regeneration and regulation of neurite outgrowth. Alternately spliced transcript variants have been observed for this gene. A pseudogene associated with this gene is located on chromosome 12. [provided by RefSeq, Jan 2013]

UniProt Comments for RAB13

RAB13: Could participate in polarized transport, in the assembly and/or the activity of tight junctions. Belongs to the small GTPase superfamily. Rab family.

Protein type: G protein; G protein, monomeric; G protein, monomeric, Rab

Chromosomal Location of Human Ortholog: 1q21.3

Cellular Component: cytoplasm; cytoplasmic vesicle; cytoplasmic vesicle membrane; endocytic vesicle; Golgi apparatus; lamellipodium; lateral plasma membrane; neuron projection; plasma membrane; recycling endosome; tight junction; trans-Golgi network

Molecular Function: GTP binding; GTPase activity; protein binding

Biological Process: cellular response to insulin stimulus; cortical actin cytoskeleton organization and biogenesis; endocytic recycling; endosome transport; neurite development; protein secretion; vesicle docking during exocytosis

Research Articles on RAB13

1. Inactive Rab13 appears to associate with vesicles via protein-protein interactions. Only following activation does Rab13 associate with the plasma membrane, presumably with insertion of the C-terminal prenyl group into the membrane.

Precautions

All of MyBioSource's Products are for scientific laboratory research purposes and are not for diagnostic, therapeutics, prophylactic or in vivo use. Through your purchase, you expressly represent and warrant to MyBioSource that you will properly test and use any Products purchased from MyBioSource in accordance with industry standards. MyBioSource and its authorized distributors reserve the right to refuse to process any order where we reasonably believe that the intended use will fall outside of our acceptable guidelines.

Disclaimer

While every efforts were made to ensure the accuracy of the information provided in this datasheet, MyBioSource will not be liable for any omissions or errors contained herein. MyBioSource reserves the right to make changes to this datasheet at any time without prior notice.

It is the responsibility of the customer to report product performance issues to MyBioSource within 30 days of receipt of the product. Please visit our Terms & Conditions page for more information.

Product Note

Select online data sheet information is drawn from bioinformatics databases, occasionally resulting in ambiguous or non-relevant product information. It is the responsibility of the customer to review, verify, and evaluate the information to make sure it matches their requirements before purchasing the kit. Our ELISA Kit assays are dynamic research tools and sometimes they may be updated and improved. If the format of this assay is important to you then please request the current manual or contact our technical support team with a presales inquiry before placing an order. We will confirm the current details of the assay. We cannot guarantee the sample manual posted online is the most current manual, it is intended to serve as an example only. Please refer to the instructions For Use provided with the assay kit for precise details.

Product PubMed Publications

Products associated with anti-RAB13 antibody

Reference Product	PubMed Publications
TBC1D4 antibody	>1 publications with RAB13 and TBC1D4
MYO5A antibody	>1 publications with RAB13 and MYO5A

Pathways associated with anti-RAB13 antibody

Products by Pathway	Pathway Diagram
Membrane Trafficking Pathway antibodies	Membrane Trafficking Pathway Diagram
Tight Junction Pathway antibodies	Tight Junction Pathway Diagram
Tight Junction Pathway antibodies	Tight Junction Pathway Diagram
Translocation Of GLUT4 To The Plasma Membrane Pathway antibodies	Translocation Of GLUT4 To The Plasma Membrane Pathway Diagram

Diseases associated with anti-RAB13 antibody

Disease Name	Pubmed Publications
Nervous System Diseases Antibodies	>1 publications with RAB13 and Nervous System Diseases
Disease Models, Animal Antibodies	>1 publications with RAB13 and Disease Models, Animal
Kidney Neoplasms Antibodies	>1 publications with RAB13 and Kidney Neoplasms
Brain Diseases Antibodies	>1 publications with RAB13 and Brain Diseases
Weight Gain Antibodies	>1 publications with RAB13 and Weight Gain
Carcinoma Antibodies	>1 publications with RAB13 and Carcinoma
Prostatic Diseases Antibodies	>1 publications with RAB13 and Prostatic Diseases
Neoplasms, Experimental Antibodies	>1 publications with RAB13 and Neoplasms, Experimental
Inflammation Antibodies	>1 publications with RAB13 and Inflammation
Weight Loss Antibodies	>1 publications with RAB13 and Weight Loss

Organs/Tissues associated with anti-RAB13 antibody

Organ/Tissue Name	Pubmed Publications
Kidney Antibodies	>13 publications with RAB13 and Kidney
Nerve Antibodies	>9 publications with RAB13 and Nerve
Blood Antibodies	>8 publications with RAB13 and Blood
Brain Antibodies	>5 publications with RAB13 and Brain
Testis Antibodies	>4 publications with RAB13 and Testis
Eye Antibodies	>4 publications with RAB13 and Eye
Muscle Antibodies	>3 publications with RAB13 and Muscle
Intestine Antibodies	>3 publications with RAB13 and Intestine
Spinal Cord Antibodies	>2 publications with RAB13 and Spinal Cord
Vascular Antibodies	>2 publications with RAB13 and Vascular