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ALDH1L1 Antibody – Rabbit Polyclonal

For Research Use Only. Not for use in diagnostic procedures. Catalog #: MBS418275

ALDH1L1 (Aldehyde dehydrogenase 1 family member L1) catalyzes the conversion of 10-formyltetrahydrofolate, NADP, and water to tetrahydrofolate, NADPH, and carbon dioxide. ALDH1L1 belongs to the aldehyde dehydrogenase family and is responsible for formate… More details

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Product Overview

Product Name
ALDH1L1 (Aldehyde dehydrogenase 1 family member L1), Polyclonal Antibody
Full Product Name
Anti-ALDH1L1 (Aldehyde dehydrogenase 1 family member L1) Antibody
Product Gene Name
Clonality
Polyclonal
Isotype
IgG
Host
Rabbit
Species Reactivity
Mouse
Form/Format
Liquid
Purity/Purification
Purified by antigen-specific affinity chromatography.
Concentration
1ug/ul (lot specific)
Preparation and Storage
This product is stable for several weeks at 4 degree C as an undiluted liquid. Dilute only prior to immediate use. For extended storage, aliquot contents and freeze at -20 degree C or below. Avoid cycles of freezing and thawing. Expiration date is one (1) year from date of receipt.
Molecular Weight
55,394 Da
OMIM
AF052732 mRNA
Immunogen
Polyclonal antibody produced in rabbits immunizing with a synthetic peptide corresponding to C-terminal residues of mouse ALDH1L1 (Aldehyde dehydrogenase 1 family member L1)
Storage Buffer
PBS, pH 7.4 with 0.05% sodium azide.
Applications Tested/Suitable for anti-ALDH1L1 antibody
Western Blot (WB), ELISA (EIA)

Product References and Citations for anti-ALDH1L1 antibody

Bonaldo, M.F., et al, Genome Res. 6 (9), 791-806 (1996) Oleinik, N.V. et al, Mol. Cancer Res. 1 (8),577-588 (2003) Krupenko, S.A. et al, Cell Growth Differ. 13 (5), 227-236 (2002) Hong, M., et al, Biochem. Mol. Biol. Int. 47 (3), 407-415 (1999) Suzuki, Y., et al, Gene 200 (1-2), 149-156 (1997) Champion, K.M., et al, Proc. Natl. Acad. Sci. U.S.A. 91 (24), 11338-11342 (1994) Johlin, F.C., et al, Mol. Pharmacol. 35 (6), 745-750 (1989)

Other Notes

Small volumes of anti-ALDH1L1 antibody vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.

Searchable Terms for ALDH1L1 purchase

MBS418275 is an antibody targeting ALDH1L1. Also known as Anti-ALDH1L1 (Aldehyde dehydrogenase 1 family member L1) Antibody. Reactive in Mouse. Host: Rabbit.

Additional Details

NCBI/Uniprot data below describe general gene information for ALDH1L1. It may not necessarily be applicable to this product.

NCBI GI #
NCBI GeneID
NCBI Accession #
UniProt Secondary Accession #
UniProt Related Accession #
NCBI Official Full Name
aldehyde dehydrogenase 1 family member L1 isoform 1, partial
NCBI Official Synonym Full Names
aldehyde dehydrogenase 1 family member L1
NCBI Official Symbol
ALDH1L1
NCBI Official Synonym Symbols
FDH; FTHFD; 10-fTHF; 10-FTHFDH
UniProt Protein Name
Cytosolic 10-formyltetrahydrofolate dehydrogenase
UniProt Synonym Protein Names
Aldehyde dehydrogenase family 1 member L1
UniProt Gene Name
ALDH1L1
UniProt Synonym Gene Names
FTHFD; 10-FTHFDH; FDH
NCBI Protein Information
cytosolic 10-formyltetrahydrofolate dehydrogenase

NCBI Summary for ALDH1L1

The protein encoded by this gene catalyzes the conversion of 10-formyltetrahydrofolate, nicotinamide adenine dinucleotide phosphate (NADP+), and water to tetrahydrofolate, NADPH, and carbon dioxide. The encoded protein belongs to the aldehyde dehydrogenase family. Loss of function or expression of this gene is associated with decreased apoptosis, increased cell motility, and cancer progression. There is an antisense transcript that overlaps on the opposite strand with this gene locus. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Jun 2012]
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UniProt Comments for ALDH1L1

ALDH1L1: 2 isoforms of the human protein are produced by alternative splicing

Protein type: Cofactor and Vitamin Metabolism - one carbon pool by folate; EC 1.5.1.6; Oxidoreductase

Chromosomal Location of Human Ortholog: 3q21.3

Cellular Component: cytoplasm; cytosol

Molecular Function: 4-trimethylammoniobutyraldehyde dehydrogenase activity; aldehyde dehydrogenase (NAD) activity; aminobutyraldehyde dehydrogenase activity; catalytic activity; formyltetrahydrofolate dehydrogenase activity

Biological Process: folic acid metabolic process
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Precautions

All of MyBioSource's Products are for scientific laboratory research purposes and are not for diagnostic, therapeutics, prophylactic or in vivo use. Through your purchase, you expressly represent and warrant to MyBioSource that you will properly test and use any Products purchased from MyBioSource in accordance with industry standards. MyBioSource and its authorized distributors reserve the right to refuse to process any order where we reasonably believe that the intended use will fall outside of our acceptable guidelines.

Disclaimer

While every efforts were made to ensure the accuracy of the information provided in this datasheet, MyBioSource will not be liable for any omissions or errors contained herein. MyBioSource reserves the right to make changes to this datasheet at any time without prior notice.

It is the responsibility of the customer to report product performance issues to MyBioSource within 30 days of receipt of the product. Please visit our Terms & Conditions page for more information.

Product Note

Select online data sheet information is drawn from bioinformatics databases, occasionally resulting in ambiguous or non-relevant product information. It is the responsibility of the customer to review, verify, and evaluate the information to make sure it matches their requirements before purchasing the kit. Our ELISA Kit assays are dynamic research tools and sometimes they may be updated and improved. If the format of this assay is important to you then please request the current manual or contact our technical support team with a presales inquiry before placing an order. We will confirm the current details of the assay. We cannot guarantee the sample manual posted online is the most current manual, it is intended to serve as an example only. Please refer to the instructions For Use provided with the assay kit for precise details.

Product PubMed Publications

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