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Sell/CD62L (CD62L) Antibody – Rat Monoclonal

For Research Use Only. Not for use in diagnostic procedures. Catalog #: MBS418464

CD62L, L-selectin, is a cell surface component that is a member of a family of adhesion/homing receptors which play important roles in leukocyte-endothelial cell interactions. The molecule is composed of multiple domains: one homologous to lectins, one to… More details

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Product Documentation
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Sample Manual Insert View PDF
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Testing Data View PDF
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Certificate of Analysis (COA) View PDF
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QC Report View PDF
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Material Safety Data Sheet View PDF
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Technical Datasheet View PDF
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Protocol View PDF

Product Overview

Product Name
Sell/CD62L, Monoclonal Antibody
Full Product Name
Anti-mouse Sell/CD62L Monoclonal Antibody
Product Gene Name
anti-CD62L antibody
Clonality
Monoclonal
Isotype
IgG2a
Host
Rat
Species Reactivity
Mouse
Form/Format
Liquid
Purity/Purification
Affinity Purified
Concentration
100ug/100ul (lot specific)
Specificity
The antibody is specific for a 90000 dalton lymphocyte surface receptor (murine equivalent to human L-selectin/CD62L) for high endothelial venule determinants in peripheral lymph nodes. This receptor appears to be required for lymphocyte homing into lymph nodes in vivo. The antibody binds to a determinant present in a peptide containing the 13 C terminal residues of ubiquitin. It does not bind to native ubiquitin or to ubiquitinated proteins.
Preparation and Storage
This product is stable for several weeks at 4 degree C as an undiluted liquid. Dilute only prior to immediate use. For extended storage, aliquot contents and freeze at -20 degree C or below. Avoid cycles of freezing and thawing. Expiration date is one (1) year from date of receipt.
Immunogen
38C-13 cells (a B cell lymphoma cell line derived from a C3H/eb mouse)
Storage Buffer
PBS, pH 7.4 with 0.02% sodium azide.

Product References and Citations for anti-CD62L antibody

Gallatin WM, et al. A cell-surface molecule involved in organ-specific homing of lymphocytes. Nature 304: 30-34, 1983. Siegelman M, et al. Cell surface molecule associated with lymphocyte homing is a ubiquitinated branched-chain glycoprotein. Science 231: 823-829, 1986. Wilson ME, et al. Local suppression of IFN-gamma in hepatic granulomas correlates with tissue-specific replication of Leishmania chagasi. J. Immunol. 156: 2231-2239, 1996.

Other Notes

Small volumes of anti-CD62L antibody vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.

Searchable Terms for CD62L purchase

MBS418464 is an antibody targeting CD62L. Also known as Anti-mouse Sell/CD62L Monoclonal Antibody. Reactive in Mouse. Host: Rat.
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