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Epcam/TROP-1 (TROP-1) Antibody – Mouse Monoclonal

For Research Use Only. Not for use in diagnostic procedures. Catalog #: MBS418469

A carcinoma-associated antigen and is a member of a family that includes at least two type I membrane proteins. This antigen is expressed on most normal epithelial cells and gastrointestinal carcinomas and functions as a homotypic calcium-independent cell… More details

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Product Documentation
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Sample Manual Insert View PDF
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Testing Data View PDF
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Certificate of Analysis (COA) View PDF
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QC Report View PDF
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Material Safety Data Sheet View PDF
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Technical Datasheet View PDF
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Protocol View PDF

Product Overview

Product Name
EpCAM/TROP-1, Monoclonal Antibody
Full Product Name
Anti-human EpCAM/TROP-1 Monoclonal Antibody
Product Gene Name
Product Synonym Gene Name
EpCAM
Clonality
Monoclonal
Isotype
IgG2a
Host
Mouse
Species Reactivity
Human
Form/Format
Liquid
Purity/Purification
Affinity Purified
Concentration
100ug/100ul (lot specific)
Specificity
The antibody reacts with Trop-1 present on trophoblast cells and on human choriocarcinomas. The antigen has also been detected on 4 of 4 human choriocarcinoma cell lines tested, on a fibrosarcoma cell line (HT1080C), on an erythroleukemia cell line (K562) and on the majority of human malignant epithelial cells and fetal epithelial precursors.
Preparation and Storage
This product is stable for several weeks at 4 degree C as an undiluted liquid. Dilute only prior to immediate use. For extended storage, aliquot contents and freeze at -20 degree C or below. Avoid cycles of freezing and thawing. Expiration date is one (1) year from date of receipt.
Immunogen
Human choriocarcinoma cell line BeWo
Storage Buffer
PBS, pH 7.4 with 0.02% sodium azide.
Applications Tested/Suitable for anti-TROP-1 antibody
Immunocytochemistry (ICC), Immunofluorescence (IF)

Immunohistochemistry (IHC) of anti-TROP-1 antibody

Mouse Anti-TROP-1 Monoclonal Antibody – Cat# MBS418469

Product References and Citations for anti-TROP-1 antibody

Lipinski M, et al. Human trophoblast cell-surface antigens defined by monoclonal antibodies. Proc. Natl. Acad. Sci. USA 78: 5147-5150, 1981. Strnad J, et al. Molecular cloning and characterization of a human adenocarcinoma/epithelial cell surface antigen complementary DNA. Cancer Res. 49: 314-317, 1989. Klein CE, et al. Expression of 38-kD cell-surface glycoprotein in transformed human keratinocyte cell lines, basal cell carcinomas, and epithelial germs. J. Invest. Dermatol. 95: 74-82, 1990.

Other Notes

Small volumes of anti-TROP-1 antibody vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.

Searchable Terms for TROP-1 purchase

MBS418469 is an antibody targeting TROP-1. Also known as Anti-human EpCAM/TROP-1 Monoclonal Antibody. Reactive in Human. Host: Mouse.
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